{"id":1044,"date":"2026-02-23T18:42:01","date_gmt":"2026-02-23T09:42:01","guid":{"rendered":"https:\/\/gmc.kumamoto.jp\/hypertension\/?p=1044"},"modified":"2026-04-08T00:15:17","modified_gmt":"2026-04-07T15:15:17","slug":"antihypertensive-drugs-list","status":"publish","type":"post","link":"https:\/\/gmc.kumamoto.jp\/hypertension\/antihypertensive-drugs-list\/","title":{"rendered":"\u9ad8\u8840\u5727\u306e\u85ac(\u964d\u5727\u85ac)\u4e00\u89a7\u3092\u308f\u304b\u308a\u3084\u3059\u304f\u89e3\u8aac\uff01\u7a2e\u985e\u5225\u306e\u7279\u5fb4\u3068\u9078\u3073\u65b9"},"content":{"rendered":"\n<p>\u5065\u5eb7\u8a3a\u65ad\u3067\u300c\u8840\u5727\u304c\u9ad8\u3044\u3067\u3059\u306d\u300d\u3068\u8a00\u308f\u308c\u305f\u3068\u304d\u3001\u591a\u304f\u306e\u65b9\u304c\u4e0d\u5b89\u3092\u611f\u3058\u308b\u306e\u3067\u306f\u306a\u3044\u3067\u3057\u3087\u3046\u304b\u3002<\/p>\n\n\n\n<p>\u300c\u85ac\u3092\u98f2\u307e\u306a\u3051\u308c\u3070\u3044\u3051\u306a\u3044\u306e\u304b\u300d\u300c\u3069\u3093\u306a\u85ac\u304c\u3042\u308b\u306e\u304b\u300d\u300c\u526f\u4f5c\u7528\u306f\u5927\u4e08\u592b\u306a\u306e\u304b\u300d\u300c\u4e00\u751f\u98f2\u307f\u7d9a\u3051\u306a\u3051\u308c\u3070\u306a\u3089\u306a\u3044\u306e\u304b\u300d\u3068\u3044\u3063\u305f\u7591\u554f\u304c\u6b21\u3005\u3068\u6d6e\u304b\u3093\u3067\u304f\u308b\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p><span class=\"swl-marker mark_orange\"><strong>\u9ad8\u8840\u5727\u306e\u6cbb\u7642\u306b\u4f7f\u308f\u308c\u308b\u85ac\u306f\u300c\u964d\u5727\u85ac(\u3053\u3046\u3042\u3064\u3084\u304f)\u300d\u3068\u547c\u3070\u308c\u3001\u8840\u5727\u3092\u4e0b\u3052\u308b\u4ed5\u7d44\u307f\u3084\u7279\u5fb4\u304c\u7570\u306a\u308b\u8907\u6570\u306e\u7a2e\u985e\u304c\u3042\u308a\u307e\u3059\u3002<\/strong><\/span><\/p>\n\n\n\n<p>\u5927\u304d\u304f\u5206\u3051\u308b\u30686\u3064\u306e\u30bf\u30a4\u30d7\u304c\u3042\u308a\u3001\u305d\u308c\u305e\u308c\u306b\u5f97\u610f\u306a\u50cd\u304d\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"swell-block-capbox cap_box is-style-onborder_ttl\"><div class=\"cap_box_ttl\"><span>\u964d\u5727\u85ac\u306e\u7a2e\u985e\u4e00\u89a7<\/span><\/div><div class=\"cap_box_content\">\n<ul class=\"wp-block-list\">\n<li><strong>\u30ab\u30eb\u30b7\u30a6\u30e0\u62ee\u6297\u85ac<\/strong> &#8211; \u8840\u7ba1\u3092\u5e83\u3052\u3066\u8840\u5727\u3092\u4e0b\u3052\u308b\u65e5\u672c\u3067\u6700\u591a\u306e\u85ac<\/li>\n\n\n\n<li><strong>ARB<\/strong> &#8211; \u8840\u7ba1\u53ce\u7e2e\u7269\u8cea\u3092\u30d6\u30ed\u30c3\u30af\u3001\u526f\u4f5c\u7528\u5c11\u306a\u304f\u814e\u81d3\u4fdd\u8b77\u52b9\u679c\u3042\u308a<\/li>\n\n\n\n<li><strong>ACE\u963b\u5bb3\u85ac<\/strong> &#8211; \u8840\u5727\u4e0a\u6607\u7269\u8cea\u306e\u751f\u6210\u6291\u5236\u3001\u7cd6\u5c3f\u75c5\u6027\u814e\u75c7\u306b\u6709\u52b9<\/li>\n\n\n\n<li><strong>\u5229\u5c3f\u85ac<\/strong> &#8211; \u4f53\u5185\u306e\u4f59\u5206\u306a\u6c34\u5206\u3068\u5869\u5206\u3092\u6392\u51fa\u3001\u4ed6\u5264\u4f75\u7528\u3067\u52b9\u679c\u5897\u5f37<\/li>\n\n\n\n<li><strong>\u03b2\u906e\u65ad\u85ac<\/strong> &#8211; \u5fc3\u62cd\u6570\u3092\u6291\u5236\u3001\u5fc3\u7b4b\u6897\u585e\u5f8c\u3084\u5fc3\u4e0d\u5168\u306e\u6cbb\u7642\u306b\u4f7f\u7528<\/li>\n\n\n\n<li><strong>\u03b1\u906e\u65ad\u85ac<\/strong> &#8211; \u8840\u7ba1\u3092\u5e83\u3052\u308b\u4f5c\u7528\u3001\u524d\u7acb\u817a\u80a5\u5927\u75c7\u3092\u4f34\u3046\u7537\u6027\u306b\u6709\u7528<\/li>\n<\/ul>\n<\/div><\/div>\n\n\n\n<p>\u304a\u533b\u8005\u3055\u3093\u306f\u3001\u60a3\u8005\u3055\u3093\u306e\u5e74\u9f62\u3084\u8840\u5727\u306e\u9ad8\u3055\u3001\u4ed6\u306b\u304b\u304b\u3063\u3066\u3044\u308b\u75c5\u6c17\u304c\u3042\u308b\u304b\u3069\u3046\u304b\u306a\u3069\u3092\u7dcf\u5408\u7684\u306b\u898b\u3066\u3001\u305d\u306e\u4eba\u306b\u6700\u3082\u5408\u3063\u305f\u85ac\u3092\u9078\u3073\u307e\u3059\u3002<\/p>\n\n\n\n<p><span class=\"swl-marker mark_orange\"><strong>\u305f\u3068\u3048\u3070\u3001\u82e5\u3044\u4eba\u3068\u9ad8\u9f62\u8005\u3067\u306f\u9055\u3046\u85ac\u304c\u9078\u3070\u308c\u308b\u3053\u3068\u304c\u591a\u304f\u3001\u7cd6\u5c3f\u75c5\u3084\u814e\u81d3\u75c5\u304c\u3042\u308b\u4eba\u306b\u306f\u305d\u308c\u3089\u306e\u75c5\u6c17\u306b\u3082\u826f\u3044\u5f71\u97ff\u304c\u3042\u308b\u85ac\u304c\u9078\u3070\u308c\u307e\u3059\u3002<\/strong><\/span><\/p>\n\n\n\n<p>\u65e5\u672c\u3067\u306f\u3001\u4e0a\u306e\u8840\u5727(\u53ce\u7e2e\u671f\u8840\u5727)\u304c140mmHg\u4ee5\u4e0a\u306e\u65b9\u306e\u5272\u5408\u306f\u3001<a href=\"https:\/\/www.mhlw.go.jp\/content\/10900000\/001338334.pdf\">\u7537\u6027\u3067\u7d0430%\u3001\u5973\u6027\u3067\u7d0425%<\/a>\u306b\u306e\u307c\u308a\u3001\u304a\u3088\u305d3450\u4e07\u4eba\u306e\u65b9\u304c\u5f53\u3066\u306f\u307e\u308b\u3068\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u9ad8\u8840\u5727\u306f\u81ea\u899a\u75c7\u72b6\u304c\u307b\u3068\u3093\u3069\u306a\u3044\u305f\u3081\u300c\u9759\u304b\u306a\u6bba\u3057\u5c4b(\u30b5\u30a4\u30ec\u30f3\u30c8\u30ad\u30e9\u30fc)\u300d\u3068\u547c\u3070\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u305d\u306e\u307e\u307e\u653e\u3063\u3066\u304a\u304f\u3068\u8133\u5352\u4e2d\u3084\u5fc3\u7b4b\u6897\u585e\u3001\u5fc3\u4e0d\u5168\u3001\u814e\u81d3\u75c5\u306a\u3069\u306e\u91cd\u5927\u306a\u75c5\u6c17\u3092\u5f15\u304d\u8d77\u3053\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3057\u304b\u3057\u3001\u304d\u3061\u3093\u3068\u6cbb\u7642\u3059\u308c\u3070\u3001<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/2676257\/\">\u8133\u5352\u4e2d\u306b\u306a\u308b\u30ea\u30b9\u30af\u3092\u7d0440%\u3001\u5fc3\u81d3\u306e\u75c5\u6c17\u306b\u306a\u308b\u30ea\u30b9\u30af\u3092\u7d0420%<\/a>\u6e1b\u3089\u3059\u3053\u3068\u304c\u3067\u304d\u308b\u3068\u3044\u3046\u7814\u7a76\u7d50\u679c\u304c\u51fa\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3064\u307e\u308a\u3001\u964d\u5727\u85ac\u306f\u3053\u3046\u3057\u305f\u6016\u3044\u75c5\u6c17\u3092\u9632\u3050\u305f\u3081\u306e\u5927\u5207\u306a\u85ac\u306a\u306e\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u3053\u306e\u8a18\u4e8b\u3067\u306f\u3001\u964d\u5727\u85ac\u306e\u4e3b\u306a\u7a2e\u985e\u3068\u305d\u308c\u305e\u308c\u306e\u7279\u5fb4\u3001\u5e74\u9f62\u3084\u6301\u75c5\u306b\u3088\u308b\u9078\u3073\u65b9\u306e\u9055\u3044\u3001\u6b63\u3057\u3044\u98f2\u307f\u65b9\u3001\u526f\u4f5c\u7528\u304c\u51fa\u305f\u3068\u304d\u306e\u5bfe\u51e6\u6cd5\u306a\u3069\u3001\u964d\u5727\u85ac\u306b\u3064\u3044\u3066\u77e5\u3063\u3066\u304a\u304f\u3079\u304d\u60c5\u5831\u3092\u3001\u3067\u304d\u308b\u3060\u3051\u308f\u304b\u308a\u3084\u3059\u304f\u8aac\u660e\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u964d\u5727\u85ac\u306b\u3064\u3044\u3066\u6b63\u3057\u3044\u77e5\u8b58\u3092\u6301\u3064\u3053\u3068\u3067\u3001\u6cbb\u7642\u3078\u306e\u4e0d\u5b89\u304c\u8efd\u304f\u306a\u308a\u3001\u3088\u308a\u5b89\u5fc3\u3057\u3066\u85ac\u3092\u98f2\u307f\u7d9a\u3051\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u3067\u3057\u3087\u3046\u3002<\/p>\n\n\n\n<div class=\"swell-block-capbox cap_box is-style-onborder_ttl2\"><div class=\"cap_box_ttl\"><span>\u3053\u306e\u8a18\u4e8b\u3067\u308f\u304b\u308b\u3053\u3068<\/span><\/div><div class=\"cap_box_content\">\n<ul class=\"wp-block-list\">\n<li>\u964d\u5727\u85ac\u306e\u4e3b\u306a6\u3064\u306e\u30bf\u30a4\u30d7\u3068\u305d\u308c\u305e\u308c\u306e\u7279\u5fb4<\/li>\n\n\n\n<li>\u5e74\u9f62\u3084\u6301\u75c5\u306b\u3088\u3063\u3066\u5408\u3046\u85ac\u304c\u9055\u3046\u7406\u7531<\/li>\n\n\n\n<li>\u964d\u5727\u85ac\u3092\u5b89\u5168\u306b\u98f2\u3080\u305f\u3081\u306e\u6ce8\u610f\u70b9<\/li>\n\n\n\n<li>\u3088\u304f\u3042\u308b\u526f\u4f5c\u7528\u3068\u305d\u306e\u5bfe\u51e6\u6cd5<\/li>\n<\/ul>\n<\/div><\/div>\n\n\n<aside class=\"c-blog-parts-aside c-blog-parts-aside--1475\" data-blog-parts-id=\"1475\"><div class=\"p-blogParts post_content\" data-partsID=\"1475\">\n<div class=\"swell-block-capbox cap_box is-style-intext\" data-colset=\"col2\"><div class=\"cap_box_ttl\"><span><strong><span class=\"swl-fz u-fz-xl\">\u85ac\u306e\u526f\u4f5c\u7528\u3084\u98f2\u307f\u5408\u308f\u305b\u304c\u4e0d\u5b89\u306a\u65b9\u3078<\/span><\/strong><\/span><\/div><div class=\"cap_box_content\">\n<p>\u6b21\u306e\u3088\u3046\u306a\u5834\u5408\u306f\u3001\u307e\u305aLINE\u3067\u85ac\u306e\u4e0d\u5b89\u3092\u6574\u7406\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list -list-under-dashed\">\n<li>\u526f\u4f5c\u7528\u304b\u3082\u3057\u308c\u306a\u3044\u75c7\u72b6\u304c\u3042\u308b<\/li>\n\n\n\n<li>\u4ed6\u306e\u85ac\u3084\u30b5\u30d7\u30ea\u3068\u4e00\u7dd2\u3067\u3088\u3044\u304b\u4e0d\u5b89<\/li>\n\n\n\n<li>\u4eca\u306e\u85ac\u3092\u7d9a\u3051\u3066\u3088\u3044\u304b\u8ff7\u3063\u3066\u3044\u308b<\/li>\n<\/ul>\n\n\n\n<p>\u5fc5\u8981\u306a\u5834\u5408\u306e\u307f\u3001\u30aa\u30f3\u30e9\u30a4\u30f3\u8a3a\u7642\u307e\u3067\u3054\u6848\u5185\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"wp-block-columns\">\n<div class=\"wp-block-column\" style=\"flex-basis:66.66%\">\n<div class=\"swell-block-button -size-custom is-style-btn_normal\" style=\"--the-width:100%\" data-align=\"left\"><a href=\"https:\/\/liff.line.me\/2001059428-MqJqm0OA\/landing?follow=%40326nxfjy&amp;lp=jtZB0m&amp;liff_id=2001059428-MqJqm0OA\" class=\"swell-block-button__link\"><span>LINE\u3067\u85ac\u306e\u4e0d\u5b89\u3092\u6574\u7406\u3059\u308b<\/span><\/a><\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column\" style=\"flex-basis:33.33%\">\n<div class=\"swell-block-button -size-custom is-style-btn_line\" style=\"--the-width:100%\" data-align=\"left\"><a href=\"https:\/\/gmc.kumamoto.jp\/hypertension\/\" class=\"swell-block-button__link\"><span>\u8cbb\u7528\u30fb\u6d41\u308c\u3092\u898b\u308b<\/span><\/a><\/div>\n<\/div>\n<\/div>\n<\/div><\/div>\n<\/div><\/aside>\n\n\n\n<details class=\"wp-block-details is-layout-flow wp-block-details-is-layout-flow\"><summary>\u306f\u3058\u3081\u306b\uff08\u514d\u8cac\u30fb\u6ce8\u610f\u4e8b\u9805\uff09<\/summary>\n<p>\u672c\u8a18\u4e8b\u306f\u3001\u9ad8\u8840\u5727\u306b\u95a2\u3059\u308b\u4e00\u822c\u7684\u306a\u533b\u5b66\u60c5\u5831\u306e\u63d0\u4f9b\u3092\u76ee\u7684\u3068\u3057\u3066\u4f5c\u6210\u3055\u308c\u305f\u3082\u306e\u3067\u3042\u308a\u3001\u7279\u5b9a\u306e\u8a3a\u65ad\u30fb\u6cbb\u7642\u3092\u63a8\u5968\u3059\u308b\u3082\u306e\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p>\u8840\u5727\u306e\u72b6\u614b\u3084\u6cbb\u7642\u65b9\u91dd\u306f\u3001\u5e74\u9f62\u30fb\u4f53\u8cea\u30fb\u57fa\u790e\u75be\u60a3\u30fb\u670d\u85ac\u72b6\u6cc1\u306a\u3069\u306b\u3088\u308a\u500b\u4eba\u5dee\u304c\u3042\u308a\u307e\u3059\u3002\u964d\u5727\u85ac\u3092\u542b\u3080\u533b\u85ac\u54c1\u306e\u4f7f\u7528\u3084\u751f\u6d3b\u7fd2\u6163\u306e\u6539\u5584\u3092\u691c\u8a0e\u3055\u308c\u308b\u5834\u5408\u306f\u3001\u5fc5\u305a\u533b\u5e2b\u306a\u3069\u306e\u533b\u7642\u5c02\u9580\u8077\u306b\u3054\u76f8\u8ac7\u306e\u3046\u3048\u3001\u5341\u5206\u306a\u8aac\u660e\u3092\u53d7\u3051\u3066\u304b\u3089\u3054\u81ea\u8eab\u306e\u5224\u65ad\u3067\u884c\u3063\u3066\u304f\u3060\u3055\u3044\u3002<\/p>\n\n\n\n<p>\u307e\u305f\u3001\u672c\u8a18\u4e8b\u3067\u7d39\u4ecb\u3059\u308b\u5185\u5bb9\u306e\u4e00\u90e8\u306f\u3001\u4e00\u822c\u8a3a\u7642\u306e\u307b\u304b\u81ea\u7531\u8a3a\u7642\u306b\u8a72\u5f53\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u4fdd\u967a\u9069\u7528\u306e\u6709\u7121\u3084\u8cbb\u7528\u3001\u52b9\u679c\u3001\u526f\u4f5c\u7528\u306a\u3069\u306b\u3064\u3044\u3066\u306f\u3001\u5fc5\u305a\u53d7\u8a3a\u5148\u306e\u533b\u7642\u6a5f\u95a2\u3067\u6700\u65b0\u306e\u60c5\u5831\u3092\u3054\u78ba\u8a8d\u304f\u3060\u3055\u3044\u3002<\/p>\n\n\n\n<p>\u672c\u8a18\u4e8b\u306e\u60c5\u5831\u306f\u516c\u958b\u6642\u70b9\u306e\u533b\u5b66\u7684\u77e5\u898b\u3084\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u3092\u3082\u3068\u306b\u3057\u3066\u3044\u307e\u3059\u304c\u3001\u4eca\u5f8c\u306e\u7814\u7a76\u3084\u6cd5\u4ee4\u6539\u6b63\u306b\u3088\u308a\u5185\u5bb9\u304c\u5909\u66f4\u3068\u306a\u308b\u5834\u5408\u304c\u3042\u308a\u307e\u3059\u3002\u6b63\u78ba\u304b\u3064\u6700\u65b0\u306e\u60c5\u5831\u3092\u5f97\u308b\u305f\u3081\u306b\u3001\u516c\u7684\u6a5f\u95a2\uff08\u539a\u751f\u52b4\u50cd\u7701\u3001\u65e5\u672c\u9ad8\u8840\u5727\u5b66\u4f1a\u306a\u3069\uff09\u3084\u5404\u533b\u7642\u6a5f\u95a2\u306e\u516c\u5f0f\u60c5\u5831\u3092\u3042\u308f\u305b\u3066\u3054\u78ba\u8a8d\u304f\u3060\u3055\u3044\u3002<\/p>\n<\/details>\n\n\n\n<h2 class=\"wp-block-heading\">\u964d\u5727\u85ac\u306f6\u3064\u306e\u30bf\u30a4\u30d7\u306b\u5206\u985e\u3055\u308c\u308b<\/h2>\n\n\n\n<p>\u964d\u5727\u85ac\u306f\u3001\u8840\u5727\u3092\u4e0b\u3052\u308b\u4ed5\u7d44\u307f\u306b\u3088\u3063\u3066\u5927\u304d\u304f6\u3064\u306e\u30bf\u30a4\u30d7\u306b\u5206\u3051\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u8840\u7ba1\u3092\u5e83\u3052\u3066\u8840\u5727\u3092\u4e0b\u3052\u308b\u3082\u306e\u3001\u4f53\u306e\u4e2d\u306e\u4f59\u5206\u306a\u6c34\u5206\u3068\u5869\u5206\u3092\u5916\u306b\u51fa\u3059\u3082\u306e\u3001\u5fc3\u81d3\u306e\u50cd\u304d\u3092\u8abf\u6574\u3059\u308b\u3082\u306e\u306a\u3069\u3001\u305d\u308c\u305e\u308c\u9055\u3063\u305f\u65b9\u6cd5\u3067\u8840\u5727\u3092\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u65e5\u672c\u306e\u9ad8\u8840\u5727\u6cbb\u7642\u306e\u5c02\u9580\u5bb6\u305f\u3061\u304c\u4f5c\u3063\u305f\u300c<a href=\"https:\/\/www.jpnsh.jp\/data\/jsh2019_gen.pdf\">\u9ad8\u8840\u5727\u6cbb\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f32019<\/a>\u300d\u3067\u306f\u3001<span class=\"swl-marker mark_orange\"><strong>\u30ab\u30eb\u30b7\u30a6\u30e0\u62ee\u6297\u85ac\u3001ARB\u3001ACE\u963b\u5bb3\u85ac\u3001\u5229\u5c3f\u85ac\u306e4\u7a2e\u985e\u3092\u300c\u6700\u521d\u306b\u4f7f\u3046\u3079\u304d\u85ac\u300d\u3068\u3057\u3066\u63a8\u5968<\/strong><\/span>\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3053\u308c\u3089\u306f\u9ad8\u8840\u5727\u306e\u6cbb\u7642\u3092\u59cb\u3081\u308b\u3068\u304d\u306b\u6700\u521d\u306b\u9078\u3070\u308c\u308b\u3053\u3068\u304c\u591a\u3044\u85ac\u3067\u3001\u305f\u304f\u3055\u3093\u306e\u7814\u7a76\u3067\u305d\u306e\u52b9\u679c\u3068\u5b89\u5168\u6027\u304c\u78ba\u304b\u3081\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p><span class=\"swl-marker mark_orange\"><strong>\u03b2\u906e\u65ad\u85ac<\/strong><\/span>\u3068<span class=\"swl-marker mark_orange\"><strong>\u03b1\u906e\u65ad\u85ac<\/strong><\/span>\u306f\u3001\u5fc3\u81d3\u306e\u75c5\u6c17\u306a\u3069\u7279\u5b9a\u306e\u75c5\u6c17\u3082\u4e00\u7dd2\u306b\u6301\u3063\u3066\u3044\u308b\u5834\u5408\u3084\u3001\u6700\u521d\u306e\u85ac\u3067\u306f\u5341\u5206\u306b\u8840\u5727\u304c\u4e0b\u304c\u3089\u306a\u304b\u3063\u305f\u5834\u5408\u306b\u4f7f\u308f\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"swell-block-capbox cap_box is-style-onborder_ttl\"><div class=\"cap_box_ttl\"><span>\u964d\u5727\u85ac\u306e6\u3064\u306e\u30bf\u30a4\u30d7<\/span><\/div><div class=\"cap_box_content\">\n<ul class=\"wp-block-list\">\n<li><strong>\u30ab\u30eb\u30b7\u30a6\u30e0\u62ee\u6297\u85ac<\/strong> &#8211; \u8840\u7ba1\u3092\u5e83\u3052\u3066\u8840\u5727\u3092\u4e0b\u3052\u308b(\u65e5\u672c\u3067\u6700\u3082\u591a\u304f\u4f7f\u308f\u308c\u3066\u3044\u308b)<\/li>\n\n\n\n<li><strong>ARB(\u30a2\u30f3\u30b8\u30aa\u30c6\u30f3\u30b7\u30f3II\u53d7\u5bb9\u4f53\u62ee\u6297\u85ac)<\/strong> &#8211; \u8840\u7ba1\u3092\u53ce\u7e2e\u3055\u305b\u308b\u7269\u8cea\u3092\u30d6\u30ed\u30c3\u30af\u3057\u3066\u8840\u5727\u3092\u4e0b\u3052\u308b<\/li>\n\n\n\n<li><strong>ACE\u963b\u5bb3\u85ac<\/strong> &#8211; \u8840\u5727\u3092\u4e0a\u3052\u308b\u7269\u8cea\u304c\u3067\u304d\u308b\u306e\u3092\u9632\u3044\u3067\u8840\u5727\u3092\u4e0b\u3052\u308b<\/li>\n\n\n\n<li><strong>\u5229\u5c3f\u85ac<\/strong> &#8211; \u4f53\u306e\u4f59\u5206\u306a\u6c34\u5206\u3068\u5869\u5206\u3092\u5c3f\u3068\u3057\u3066\u51fa\u3057\u3066\u8840\u5727\u3092\u4e0b\u3052\u308b<\/li>\n\n\n\n<li><strong>\u03b2\u906e\u65ad\u85ac<\/strong> &#8211; \u5fc3\u81d3\u306e\u62cd\u52d5\u3092\u6291\u3048\u3066\u8840\u5727\u3092\u4e0b\u3052\u308b<\/li>\n\n\n\n<li><strong>\u03b1\u906e\u65ad\u85ac<\/strong> &#8211; \u8840\u7ba1\u3092\u5e83\u3052\u3066\u8840\u5727\u3092\u4e0b\u3052\u308b<\/li>\n<\/ul>\n<\/div><\/div>\n\n\n\n<p>\u305d\u308c\u305e\u308c\u306e\u85ac\u306b\u306f\u5f97\u610f\u306a\u50cd\u304d\u304c\u3042\u3063\u3066\u3001\u60a3\u8005\u3055\u3093\u306e\u72b6\u614b\u306b\u5408\u308f\u305b\u3066\u4f7f\u3044\u5206\u3051\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u305f\u3068\u3048\u3070\u3001<span class=\"swl-marker mark_orange\"><strong>\u30ab\u30eb\u30b7\u30a6\u30e0\u62ee\u6297\u85ac<\/strong><\/span>\u306f\u5e74\u9f62\u3084\u56fd\u7c4d\u306b\u95a2\u4fc2\u306a\u304f\u591a\u304f\u306e\u4eba\u306b\u52b9\u679c\u304c\u671f\u5f85\u3067\u304d\u308b\u305f\u3081<a href=\"https:\/\/www.nature.com\/articles\/s41440-019-0238-2\">\u65e5\u672c\u3067\u4e00\u756a\u3088\u304f\u4f7f\u308f\u308c\u3066\u304a\u308a<\/a>\u3001<span class=\"swl-marker mark_orange\"><strong>ARB<\/strong><\/span>\u3084<span class=\"swl-marker mark_orange\"><strong>ACE\u963b\u5bb3\u85ac<\/strong><\/span>\u306f\u814e\u81d3\u3084\u5fc3\u81d3\u3092\u5b88\u308b\u52b9\u679c\u304c\u3042\u308b\u305f\u3081\u7cd6\u5c3f\u75c5\u3084\u814e\u81d3\u75c5\u306e\u3042\u308b\u65b9\u306b\u5411\u3044\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p><span class=\"swl-marker mark_orange\"><strong>\u5229\u5c3f\u85ac<\/strong><\/span>\u306f\u4ed6\u306e\u85ac\u3068\u4e00\u7dd2\u306b\u4f7f\u3046\u3053\u3068\u3067\u8840\u5727\u3092\u4e0b\u3052\u308b\u52b9\u679c\u3092\u3050\u3063\u3068\u9ad8\u3081\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u5927\u5207\u306a\u306e\u306f\u3001\u85ac\u306e\u52b9\u679c\u306f\u7a2e\u985e\u3088\u308a\u3082\u300c\u3069\u308c\u3060\u3051\u8840\u5727\u3092\u4e0b\u3052\u3089\u308c\u308b\u304b\u300d\u3067\u6c7a\u307e\u308b\u3068\u3044\u3046\u3053\u3068\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u3064\u307e\u308a\u3001\u81ea\u5206\u306b\u5408\u3063\u305f\u85ac\u3092\u898b\u3064\u3051\u3066\u3001\u76ee\u6a19\u3068\u3059\u308b\u8840\u5727\u306e\u5024\u307e\u3067\u3057\u3063\u304b\u308a\u3068\u4e0b\u3052\u308b\u3053\u3068\u304c\u4f55\u3088\u308a\u91cd\u8981\u306a\u306e\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u3067\u306f\u3001\u305d\u308c\u305e\u308c\u306e\u964d\u5727\u85ac\u306b\u3064\u3044\u3066\u8a73\u3057\u304f\u898b\u3066\u3044\u304d\u307e\u3057\u3087\u3046\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u30ab\u30eb\u30b7\u30a6\u30e0\u62ee\u6297\u85ac\u306f\u65e5\u672c\u3067\u3082\u3063\u3068\u3082\u591a\u304f\u51e6\u65b9\u3055\u308c\u3066\u3044\u308b\u964d\u5727\u85ac<\/h3>\n\n\n\n<p><span class=\"swl-marker mark_orange\"><strong>\u30ab\u30eb\u30b7\u30a6\u30e0\u62ee\u6297\u85ac\u306f\u3001\u65e5\u672c\u3067\u4e00\u756a\u3088\u304f\u4f7f\u308f\u308c\u3066\u3044\u308b\u964d\u5727\u85ac\u3067\u3059\u3002<\/strong><\/span><\/p>\n\n\n\n<p>\u8840\u7ba1\u306e\u58c1\u3092\u4f5c\u3063\u3066\u3044\u308b\u7d30\u80de\u306b\u30ab\u30eb\u30b7\u30a6\u30e0\u304c\u5165\u308a\u8fbc\u3080\u306e\u3092\u9632\u3050\u3053\u3068\u3067\u3001<a href=\"https:\/\/www.sciencedirect.com\/topics\/pharmacology-toxicology-and-pharmaceutical-science\/calcium-channel-blocker-toxicity\">\u8840\u7ba1\u3092\u5e83\u3052\u3066\u8840\u5727\u3092\u4e0b\u3052\u307e\u3059<\/a>\u3002<\/p>\n\n\n\n<div class=\"swell-block-capbox cap_box is-style-onborder_ttl\"><div class=\"cap_box_ttl\"><span>\u4ee3\u8868\u7684\u306a\u85ac<\/span><\/div><div class=\"cap_box_content\">\n<ul class=\"wp-block-list\">\n<li>\u30a2\u30e0\u30ed\u30b8\u30d4\u30f3(\u5546\u54c1\u540d:\u30ce\u30eb\u30d0\u30b9\u30af\u3001\u30a2\u30e0\u30ed\u30b8\u30f3)<\/li>\n\n\n\n<li>\u30cb\u30d5\u30a7\u30b8\u30d4\u30f3(\u5546\u54c1\u540d:\u30a2\u30c0\u30e9\u30fc\u30c8CR)<\/li>\n\n\n\n<li>\u30a2\u30bc\u30eb\u30cb\u30b8\u30d4\u30f3<\/li>\n\n\n\n<li>\u30d9\u30cb\u30b8\u30d4\u30f3<\/li>\n<\/ul>\n<\/div><\/div>\n\n\n\n<p>\u3053\u306e\u85ac\u306e\u4e00\u756a\u306e\u7279\u5fb4\u306f\u3001\u82e5\u3044\u4eba\u3067\u3082\u9ad8\u9f62\u8005\u3067\u3082\u3001\u591a\u304f\u306e\u4eba\u306b\u52b9\u679c\u304c\u671f\u5f85\u3067\u304d\u308b\u3053\u3068\u3067\u3059\u3002<\/p>\n\n\n\n<p><span class=\"swl-marker mark_orange\"><strong>\u4eba\u306b\u3088\u3063\u3066\u52b9\u304d\u3084\u3059\u3044\u30fb\u52b9\u304d\u306b\u304f\u3044\u3068\u3044\u3046\u5dee\u304c\u6bd4\u8f03\u7684\u5c11\u306a\u3044\u305f\u3081\u3001\u6700\u521d\u306b\u9078\u3070\u308c\u308b\u85ac\u3068\u3057\u3066\u5e83\u304f\u4f7f\u308f\u308c\u3066\u3044\u307e\u3059\u3002<\/strong><\/span><\/p>\n\n\n\n<p>\u307e\u305f\u3001\u7cd6\u5c3f\u75c5\u3084\u8102\u8cea\u7570\u5e38\u75c7(\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3084\u4e2d\u6027\u8102\u80aa\u304c\u9ad8\u3044\u75c5\u6c17)\u304c\u3042\u308b\u65b9\u3067\u3082\u3001\u3053\u308c\u3089\u306e\u75c5\u6c17\u306e\u72b6\u614b\u3092\u60aa\u304f\u3057\u306b\u304f\u3044\u3068\u3044\u3046\u826f\u3044\u70b9\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32410171\/\">\u30a2\u30e1\u30ea\u30ab\u306e\u7814\u7a76<\/a>\u306b\u3088\u308b\u3068\u3001\u30ab\u30eb\u30b7\u30a6\u30e0\u62ee\u6297\u85ac\u306f\u4f53\u306e\u5404\u81d3\u5668\u3078\u306e\u8840\u6db2\u306e\u6d41\u308c\u3092\u4fdd\u3064\u52b9\u679c\u306b\u512a\u308c\u3066\u3044\u308b\u305f\u3081\u3001\u5fc3\u81d3\u3084\u814e\u81d3\u306b\u75c5\u6c17\u304c\u3042\u308b\u9ad8\u9f62\u8005\u306b\u3082\u4f7f\u3044\u3084\u3059\u3044\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u305f\u3060\u3057\u3001\u4e00\u90e8\u306e\u30bf\u30a4\u30d7\uff08\u30d9\u30e9\u30d1\u30df\u30eb\u3084\u30b8\u30eb\u30c1\u30a2\u30bc\u30e0\u306a\u3069\uff09\u306f\u8108\u3092\u9045\u304f\u3059\u308b\u4f5c\u7528\u304c\u3042\u308b\u305f\u3081\u3001\u3082\u3068\u3082\u3068\u8108\u304c\u9045\u3044\u65b9(\u5f90\u8108)\u306f\u4f7f\u3048\u306a\u3044\u5834\u5408\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"swell-block-capbox cap_box is-style-onborder_ttl\"><div class=\"cap_box_ttl\"><span>\u3088\u304f\u3042\u308b\u526f\u4f5c\u7528<\/span><\/div><div class=\"cap_box_content\">\n<ul class=\"wp-block-list\">\n<li>\u9854\u306e\u307b\u3066\u308a<\/li>\n\n\n\n<li>\u982d\u75db<\/li>\n\n\n\n<li>\u5fc3\u81d3\u306e\u30c9\u30ad\u30c9\u30ad(\u52d5\u60b8)<\/li>\n\n\n\n<li>\u8db3\u9996\u306e\u3080\u304f\u307f<\/li>\n\n\n\n<li>\u4fbf\u79d8(\u7279\u306b\u30d9\u30e9\u30d1\u30df\u30eb)<\/li>\n<\/ul>\n<\/div><\/div>\n\n\n\n<p>\u526f\u4f5c\u7528\u3068\u3057\u3066\u306f\u3001\u8840\u7ba1\u304c\u5e83\u304c\u308b\u3053\u3068\u306b\u3088\u3063\u3066\u3001<span class=\"swl-marker mark_orange\"><strong>\u9854\u304c\u307b\u3066\u308b\u3001\u982d\u304c\u75db\u304f\u306a\u308b\u3001\u5fc3\u81d3\u304c\u30c9\u30ad\u30c9\u30ad\u3059\u308b<\/strong><\/span>\u306a\u3069\u304c\u8d77\u3053\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u307e\u305f\u3001\u8db3\u9996\u304c\u3080\u304f\u3080\u3053\u3068\u304c\u6bd4\u8f03\u7684\u3088\u304f\u3042\u308a\u307e\u3059\u304c\u3001\u3053\u308c\u306f\u8840\u7ba1\u304c\u5e83\u304c\u308b\u3053\u3068\u3067\u8840\u6db2\u306e\u4e2d\u306e\u6c34\u5206\u304c\u8840\u7ba1\u306e\u5916\u306b\u79fb\u52d5\u3057\u3084\u3059\u304f\u306a\u308b\u305f\u3081\u306b\u8d77\u3053\u308b\u3082\u306e\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u901a\u5e38\u306f\u91cd\u7be4\u306a\u554f\u984c\u306b\u306f\u306a\u308a\u306b\u304f\u3044\u3067\u3059\u304c\u3001\u75c7\u72b6\u304c\u5f37\u3044\u5834\u5408\u306f\u533b\u5e2b\u306b\u76f8\u8ac7\u3057\u3066\u85ac\u306e\u5909\u66f4\u306a\u3069\u3092\u691c\u8a0e\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u4fbf\u79d8\u3082\u3001\u7279\u306b<a href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2016\/019614s053lbl.pdf\">\u30d9\u30e9\u30d1\u30df\u30eb\u3068\u3044\u3046\u7a2e\u985e\u306e\u30ab\u30eb\u30b7\u30a6\u30e0\u62ee\u6297\u85ac<\/a>\u3067\u3088\u304f\u8d77\u3053\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"is-style-balloon_box\">\u91cd\u8981\u306a\u6ce8\u610f\u70b9<\/p>\n\n\n\n<p>\u3053\u306e\u85ac\u306e\u4e00\u90e8(\u30b8\u30eb\u30c1\u30a2\u30bc\u30e0\u3084\u30d9\u30e9\u30d1\u30df\u30eb)\u306f <span class=\"swl-marker mark_orange\"><strong>\u30b0\u30ec\u30fc\u30d7\u30d5\u30eb\u30fc\u30c4\u3084\u30b0\u30ec\u30fc\u30d7\u30d5\u30eb\u30fc\u30c4\u30b8\u30e5\u30fc\u30b9\u3068\u4e00\u7dd2\u306b\u6442\u3063\u3066\u306f\u3044\u3051\u307e\u305b\u3093 <\/strong><\/span>\u3002<\/p>\n\n\n\n<p>\u30b0\u30ec\u30fc\u30d7\u30d5\u30eb\u30fc\u30c4\u306b\u542b\u307e\u308c\u308b\u6210\u5206\u304c\u85ac\u3092\u5206\u89e3\u3059\u308b\u50cd\u304d\u3092\u90aa\u9b54\u3057\u3066\u3057\u307e\u3044\u3001\u85ac\u306e\u6fc3\u5ea6\u304c\u4e0a\u304c\u308a\u3059\u304e\u3066\u3001\u3081\u307e\u3044\u3084\u982d\u75db\u306a\u3069\u306e\u526f\u4f5c\u7528\u304c\u5f37\u304f\u51fa\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u305f\u3081\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">ARB\u306f\u526f\u4f5c\u7528\u304c\u5c11\u306a\u304f\u9577\u671f\u9593\u5b89\u5fc3\u3057\u3066\u4f7f\u3048\u308b\u964d\u5727\u85ac<\/h3>\n\n\n\n<p><span class=\"swl-marker mark_orange\"><strong>ARB(\u30a8\u30fc\u30a2\u30fc\u30eb\u30d3\u30fc\u3001\u6b63\u5f0f\u540d\u79f0:\u30a2\u30f3\u30b8\u30aa\u30c6\u30f3\u30b7\u30f3II\u53d7\u5bb9\u4f53\u62ee\u6297\u85ac)\u306f\u3001\u526f\u4f5c\u7528\u304c\u5c11\u306a\u304f\u3001\u9577\u3044\u9593\u5b89\u5168\u306b\u4f7f\u3048\u308b\u964d\u5727\u85ac<\/strong><\/span>\u3068\u3057\u3066\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"swell-block-capbox cap_box is-style-onborder_ttl\"><div class=\"cap_box_ttl\"><span>\u4ee3\u8868\u7684\u306a\u85ac<\/span><\/div><div class=\"cap_box_content\">\n<ul class=\"wp-block-list\">\n<li>\u30aa\u30eb\u30e1\u30b5\u30eb\u30bf\u30f3(\u5546\u54c1\u540d:\u30aa\u30eb\u30e1\u30c6\u30c3\u30af)<\/li>\n\n\n\n<li>\u30d0\u30eb\u30b5\u30eb\u30bf\u30f3(\u5546\u54c1\u540d:\u30c7\u30a3\u30aa\u30d0\u30f3)<\/li>\n\n\n\n<li>\u30ed\u30b5\u30eb\u30bf\u30f3(\u5546\u54c1\u540d:\u30cb\u30e5\u30fc\u30ed\u30bf\u30f3)<\/li>\n\n\n\n<li>\u30c6\u30eb\u30df\u30b5\u30eb\u30bf\u30f3(\u5546\u54c1\u540d:\u30df\u30ab\u30eb\u30c7\u30a3\u30b9)<\/li>\n\n\n\n<li>\u30ab\u30f3\u30c7\u30b5\u30eb\u30bf\u30f3(\u5546\u54c1\u540d:\u30d6\u30ed\u30d7\u30ec\u30b9)<\/li>\n<\/ul>\n<\/div><\/div>\n\n\n\n<p>\u3053\u306e\u85ac\u306f\u3001\u8840\u7ba1\u3092\u7e2e\u3081\u3066\u8840\u5727\u3092\u4e0a\u3052\u308b\u300c\u30a2\u30f3\u30b8\u30aa\u30c6\u30f3\u30b7\u30f3II(\u30c4\u30fc)\u300d\u3068\u3044\u3046\u4f53\u306e\u4e2d\u306e\u7269\u8cea\u306e\u50cd\u304d\u3092\u76f4\u63a5\u30d6\u30ed\u30c3\u30af\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK537027\/\">\u30a2\u30f3\u30b8\u30aa\u30c6\u30f3\u30b7\u30f3II\u304c\u7d30\u80de\u306e\u30b9\u30a4\u30c3\u30c1(\u53d7\u5bb9\u4f53)\u306b\u7d50\u5408\u3059\u308b\u306e\u3092\u9632\u3050<\/a>\u3053\u3068\u3067\u3001\u8840\u7ba1\u304c\u5e83\u304c\u3063\u3066\u8840\u5727\u304c\u4e0b\u304c\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u307e\u305f\u3001\u4f53\u306e\u4e2d\u306b\u5869\u5206\u3068\u6c34\u5206\u304c\u305f\u307e\u308b\u306e\u3092\u9632\u3050\u50cd\u304d\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u30a2\u30e1\u30ea\u30ab\u306e\u533b\u5b66\u8ad6\u6587\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9\u306b\u767b\u9332\u3055\u308c\u3066\u3044\u308b\u7814\u7a76\u306b\u3088\u308b\u3068\u3001<span class=\"swl-marker mark_orange\"><strong>ARB\u306f\u8efd\u3044\u9ad8\u8840\u5727\u304b\u3089\u91cd\u3044\u9ad8\u8840\u5727\u307e\u3067\u5e45\u5e83\u304f\u52b9\u679c\u304c\u3042\u308a<\/strong><\/span>\u3001\u8840\u5727\u3092\u4e0b\u3052\u308b\u529b\u306f\u4ed6\u306e\u4e3b\u8981\u306a\u964d\u5727\u85ac\u3068\u540c\u3058\u304f\u3089\u3044\u3067\u3059\u3002<\/p>\n\n\n\n<p>ARB\u306e\u6700\u5927\u306e\u826f\u3044\u70b9\u306f\u526f\u4f5c\u7528\u304c\u5c11\u306a\u3044\u3053\u3068\u3067\u3001\u7279\u306b\u5f8c\u3067\u8aac\u660e\u3059\u308bACE\u963b\u5bb3\u85ac\u3067\u8d77\u3053\u308a\u3084\u3059\u3044\u7a7a\u54b3\u304c\u307b\u3068\u3093\u3069\u8d77\u3053\u3089\u306a\u3044\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p>ARB\u3092\u670d\u7528\u3057\u3066\u3044\u308b\u60a3\u8005\u3067\u306f\u3001\u30ea\u30b7\u30ce\u30d7\u30ea\u30eb\u3092\u670d\u7528\u3057\u3066\u3044\u308b\u60a3\u8005\u3088\u308a\u3082\u54b3\u55fd\u306e\u983b\u5ea6\u304c\u6709\u610f\u306b\u4f4e\u3044\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u308b\uff085\uff09\u3002<\/p>\n<cite>\u5f15\u7528\uff1aPubMed Central <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC1200815\/\">Angiotensin II receptor blockers<\/a><\/cite><\/blockquote>\n\n\n\n<div class=\"swell-block-capbox cap_box is-style-onborder_ttl\"><div class=\"cap_box_ttl\"><span>\u3088\u304f\u3042\u308b\u526f\u4f5c\u7528<\/span><\/div><div class=\"cap_box_content\">\n<ul class=\"wp-block-list\">\n<li>\u3081\u307e\u3044<\/li>\n\n\n\n<li>\u3075\u3089\u3064\u304d<\/li>\n\n\n\n<li>\u4f53\u306e\u3060\u308b\u3055<\/li>\n\n\n\n<li>\u307e\u308c\u306b\u8840\u6db2\u4e2d\u306e\u30ab\u30ea\u30a6\u30e0\u304c\u5897\u3048\u308b<\/li>\n<\/ul>\n<\/div><\/div>\n\n\n\n<p>ARB\u3067\u3088\u304f\u898b\u3089\u308c\u308b\u526f\u4f5c\u7528\u3068\u3057\u3066\u306f\u3001<span class=\"swl-marker mark_orange\"><strong>\u3081\u307e\u3044\u3001\u3075\u3089\u3064\u304d\u3001\u4f53\u304c\u3060\u308b\u3044<\/strong><\/span>\u306a\u3069\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3053\u308c\u3089\u306f\u8840\u5727\u304c\u4e0b\u304c\u308b\u3053\u3068\u3067\u8d77\u3053\u308b\u75c7\u72b6\u3067\u3001\u7279\u306b\u85ac\u3092\u98f2\u307f\u59cb\u3081\u305f\u3068\u304d\u3084\u3001\u5229\u5c3f\u85ac(\u5c3f\u306e\u91cf\u3092\u5897\u3084\u3059\u85ac)\u3092\u4e00\u7dd2\u306b\u4f7f\u3063\u3066\u3044\u308b\u5834\u5408\u306b\u73fe\u308c\u3084\u3059\u304f\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u307e\u305f\u3001\u307e\u308c\u306b\u8840\u6db2\u306e\u4e2d\u306e\u30ab\u30ea\u30a6\u30e0\u3068\u3044\u3046\u6210\u5206\u304c\u591a\u304f\u306a\u308a\u3059\u304e\u308b\u3053\u3068\u304c\u3042\u308b\u305f\u3081\u3001\u5b9a\u671f\u7684\u306a\u8840\u6db2\u691c\u67fb\u3067\u30c1\u30a7\u30c3\u30af\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"is-style-balloon_box\">\u91cd\u8981\u306a\u6ce8\u610f\u70b9<\/p>\n\n\n\n<p>\u5927\u5207\u306a\u6ce8\u610f\u70b9\u306f\u3001 <span class=\"swl-marker mark_orange\"><strong>\u598a\u5a20\u4e2d\u306e\u65b9\u3084\u598a\u5a20\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u5973\u6027\u306f\u4f7f\u3063\u3066\u306f\u3044\u3051\u306a\u3044<\/strong><\/span> \u3068\u3044\u3046\u3053\u3068\u3067\u3059\u3002<\/p>\n\n\n\n<p>ARB\u306f\u304a\u8179\u306e\u8d64\u3061\u3083\u3093\u306b\u91cd\u5927\u306a\u5f71\u97ff\u3092\u53ca\u307c\u3059\u53ef\u80fd\u6027\u304c\u3042\u308a\u3001\u30a2\u30e1\u30ea\u30ab\u306e\u85ac\u3092\u7ba1\u7406\u3059\u308b\u6a5f\u95a2\u3067\u3082\u539f\u5247\u907f\u3051\u308b\u3079\u304d\u3060\u3068\u660e\u8a18\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p>ACE\u963b\u5bb3\u85ac\u3068ARB\u306f\u598a\u5a20\u4e2d\u3001\u7279\u306b\u598a\u5a20\u4e2d\u671f\u3068\u5f8c\u671f\u306b\u306f\u4f7f\u7528\u3059\u3079\u304d\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u80ce\u5150\u6b7b\u4ea1\u3092\u542b\u3080\u3001\u80ce\u5150\u3078\u306e\u60aa\u5f71\u97ff\u306e\u30ea\u30b9\u30af\u3092\u9ad8\u3081\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n<cite>\u5f15\u7528\uff1aNational Kidney Foundation <a href=\"https:\/\/www.kidney.org\/kidney-topics\/ace-inhibitors-and-arbs\">ACE Inhibitors and ARBs<\/a><\/cite><\/blockquote>\n\n\n\n<p>\u598a\u5a20\u304c\u308f\u304b\u3063\u305f\u6642\u70b9\u3067\u3001\u3059\u3050\u306b\u304a\u533b\u8005\u3055\u3093\u306b\u76f8\u8ac7\u3057\u3066\u85ac\u3092\u5909\u3048\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">ACE\u963b\u5bb3\u85ac\u306f\u5fc3\u81d3\u3084\u814e\u81d3\u306e\u4fdd\u8b77\u52b9\u679c\u3082\u671f\u5f85\u3067\u304d\u308b\u964d\u5727\u85ac<\/h3>\n\n\n\n<p><span class=\"swl-marker mark_orange\"><strong>ACE\u963b\u5bb3\u85ac(\u30a8\u30fc\u30b9\u305d\u304c\u3044\u3084\u304f\u3001\u6b63\u5f0f\u540d\u79f0:\u30a2\u30f3\u30b8\u30aa\u30c6\u30f3\u30b7\u30f3\u5909\u63db\u9175\u7d20\u963b\u5bb3\u85ac)\u306f\u3001ARB\u3068\u4f3c\u305f\u4ed5\u7d44\u307f\u3067\u8840\u5727\u3092\u4e0b\u3052\u308b\u85ac\u3067\u3059\u304c\u3001\u50cd\u304d\u304b\u3051\u308b\u5834\u6240\u304c\u9055\u3044\u307e\u3059\u3002<\/strong><\/span><\/p>\n\n\n\n<div class=\"swell-block-capbox cap_box is-style-onborder_ttl\"><div class=\"cap_box_ttl\"><span>\u4ee3\u8868\u7684\u306a\u85ac<\/span><\/div><div class=\"cap_box_content\">\n<ul class=\"wp-block-list\">\n<li>\u30ab\u30d7\u30c8\u30d7\u30ea\u30eb<\/li>\n\n\n\n<li>\u30a8\u30ca\u30e9\u30d7\u30ea\u30eb<\/li>\n\n\n\n<li>\u30ea\u30b7\u30ce\u30d7\u30ea\u30eb<\/li>\n\n\n\n<li>\u30a4\u30df\u30c0\u30d7\u30ea\u30eb<\/li>\n\n\n\n<li>\u30da\u30ea\u30f3\u30c9\u30d7\u30ea\u30eb<\/li>\n<\/ul>\n<\/div><\/div>\n\n\n\n<p>\u3053\u306e\u85ac\u306f\u3001\u8840\u5727\u3092\u4e0a\u3052\u308b\u7269\u8cea\u3067\u3042\u308b\u300c\u30a2\u30f3\u30b8\u30aa\u30c6\u30f3\u30b7\u30f3II\u300d\u304c\u4f5c\u3089\u308c\u308b\u904e\u7a0b\u3067\u50cd\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<p><span class=\"swl-marker mark_orange\"><strong>\u4f53\u306e\u4e2d\u3067\u30a2\u30f3\u30b8\u30aa\u30c6\u30f3\u30b7\u30f3I\u3068\u3044\u3046\u7269\u8cea\u304b\u3089\u30a2\u30f3\u30b8\u30aa\u30c6\u30f3\u30b7\u30f3II\u3078\u5909\u308f\u308b\u3068\u304d\u306b\u5fc5\u8981\u306a\u9175\u7d20(ACE)\u306e\u50cd\u304d\u3092\u6291\u3048\u308b<\/strong><\/span>\u3053\u3068\u3067\u3001\u30a2\u30f3\u30b8\u30aa\u30c6\u30f3\u30b7\u30f3II\u304c\u3067\u304d\u308b\u306e\u3092\u6e1b\u3089\u3057\u3001\u8840\u7ba1\u3092\u5e83\u3052\u3066\u8840\u5727\u3092\u4e0b\u3052\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"swell-block-capbox cap_box is-style-onborder_ttl\"><div class=\"cap_box_ttl\"><span>\u7279\u306b\u52b9\u679c\u304c\u671f\u5f85\u3067\u304d\u308b\u65b9<\/span><\/div><div class=\"cap_box_content\">\n<ul class=\"wp-block-list\">\n<li>\u7cd6\u5c3f\u75c5\u6027\u814e\u75c7\u306e\u65b9<\/li>\n\n\n\n<li>\u30bf\u30f3\u30d1\u30af\u5c3f\u304c\u3042\u308b\u6162\u6027\u814e\u81d3\u75c5\u306e\u65b9<\/li>\n\n\n\n<li>\u5fc3\u4e0d\u5168\u306e\u65b9<\/li>\n\n\n\n<li>\u5fc3\u7b4b\u6897\u585e\u5f8c\u306e\u65b9<\/li>\n<\/ul>\n<\/div><\/div>\n\n\n\n<p>ACE\u963b\u5bb3\u85ac\u306f\u8840\u5727\u3092\u4e0b\u3052\u308b\u3060\u3051\u3067\u306a\u304f\u3001<a href=\"https:\/\/kdigo.org\/wp-content\/uploads\/2023\/04\/Diabetes-Management-in-Chronic-Kidney-Disease-Consensus-Report-by-the-ADA-and-KDIGO.pdf\">\u5fc3\u81d3\u3084\u814e\u81d3\u3092\u5b88\u308b\u50cd\u304d\u304c\u3042\u308b<\/a>\u3053\u3068\u304c\u305f\u304f\u3055\u3093\u306e\u7814\u7a76\u3067\u308f\u304b\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u7279\u306b\u7cd6\u5c3f\u75c5\u3067\u814e\u81d3\u304c\u60aa\u304f\u306a\u3063\u3066\u3044\u308b\u65b9(\u7cd6\u5c3f\u75c5\u6027\u814e\u75c7)\u3084\u3001\u5c3f\u306b\u30bf\u30f3\u30d1\u30af\u304c\u51fa\u3066\u3044\u308b\u6162\u6027\u814e\u81d3\u75c5\u306e\u65b9\u3067\u306f\u3001\u814e\u81d3\u306e\u50cd\u304d\u304c\u60aa\u304f\u306a\u308b\u306e\u3092\u9045\u3089\u305b\u308b\u52b9\u679c\u304c\u671f\u5f85\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u307e\u305f\u3001\u5fc3\u4e0d\u5168\u306e\u7d4c\u904e\u3092\u826f\u304f\u3059\u308b\u50cd\u304d\u3082\u3042\u308a\u3001<a href=\"https:\/\/professional.heart.org\/en\/science-news\/-\/media\/832EA0F4E73948848612F228F7FA2D35.ashx\">\u5fc3\u7b4b\u6897\u585e\u3092\u8d77\u3053\u3057\u305f\u5f8c\u306e\u65b9\u306b\u3082\u4f7f\u308f\u308c\u307e\u3059<\/a>\u3002<\/p>\n\n\n\n<div class=\"swell-block-capbox cap_box is-style-onborder_ttl\"><div class=\"cap_box_ttl\"><span>\u3088\u304f\u3042\u308b\u526f\u4f5c\u7528<\/span><\/div><div class=\"cap_box_content\">\n<ul class=\"wp-block-list\">\n<li>\u7a7a\u54b3<\/li>\n\n\n\n<li>\u3081\u307e\u3044<\/li>\n\n\n\n<li>\u7acb\u3061\u304f\u3089\u307f<\/li>\n\n\n\n<li>\u4f53\u306e\u3060\u308b\u3055<\/li>\n\n\n\n<li>\u307e\u308c\u306b\u8840\u7ba1\u6d6e\u816b(\u9854\u3084\u5507\u306e\u816b\u308c)<\/li>\n<\/ul>\n<\/div><\/div>\n\n\n\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/16428706\/\">\u30a2\u30e1\u30ea\u30ab\u80f8\u90e8\u75be\u60a3\u5b66\u4f1a\uff08ACCP\uff09\u306e\u30c7\u30fc\u30bf<\/a>\u306b\u3088\u308b\u3068\u3001ACE\u963b\u5bb3\u85ac\u3092\u98f2\u3093\u3067\u3044\u308b\u65b9\u306e<span class=\"swl-marker mark_orange\"><strong>5\u301c35%\u7a0b\u5ea6\u306b\u7a7a\u54b3\u304c\u73fe\u308c\u308b<\/strong><\/span>\u3068\u3044\u308f\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3053\u308c\u306f\u85ac\u304c\u30d6\u30e9\u30b8\u30ad\u30cb\u30f3\u306a\u3069\u306e\u7269\u8cea\u3092\u5206\u89e3\u3059\u308b\u306e\u3092\u90aa\u9b54\u3059\u308b\u3053\u3068\u3067\u8d77\u3053\u308b\u526f\u4f5c\u7528\u3067\u3001\u306e\u3069\u304c\u30a4\u30ac\u30a4\u30ac\u3059\u308b\u3001\u30ab\u30b5\u30ab\u30b5\u3059\u308b\u611f\u3058\u304c\u7d9a\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<p><span class=\"swl-marker mark_orange\"><strong>\u3053\u306e\u54b3\u306f\u4f53\u306b\u5bb3\u306f\u3042\u308a\u307e\u305b\u3093\u304c\u3001\u6c17\u306b\u306a\u308b\u5834\u5408\u306fARB\u306b\u5909\u3048\u308b\u3053\u3068\u3092\u691c\u8a0e\u3057\u307e\u3059\u3002<\/strong><\/span><\/p>\n\n\n\n<p>\u305d\u306e\u4ed6\u306e\u526f\u4f5c\u7528\u3068\u3057\u3066\u3001\u3081\u307e\u3044\u3001\u7acb\u3061\u304f\u3089\u307f\u3001\u4f53\u306e\u3060\u308b\u3055\u306a\u3069\u304c\u8d77\u3053\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u307e\u305f\u3001\u307e\u308c\u3067\u3059\u304c\u3001\u9854\u3084\u5507\u3001\u820c\u304c\u816b\u308c\u308b\u8840\u7ba1\u6d6e\u816b\u3068\u3044\u3046\u91cd\u3044\u526f\u4f5c\u7528\u304c\u8d77\u3053\u308b\u53ef\u80fd\u6027\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>ARB\u3068\u540c\u3058\u3067\u3001 <span class=\"swl-marker mark_orange\"><strong>\u598a\u5a20\u4e2d\u306e\u65b9\u3084\u598a\u5a20\u306e\u53ef\u80fd\u6027\u304c\u3042\u308b\u5973\u6027\u306f\u4f7f\u3048\u307e\u305b\u3093<\/strong><\/span>\u3002<\/p>\n\n\n\n<p>ACE\u963b\u5bb3\u85ac\u3082ARB\u3068\u540c\u3058\u3067\u3001\u8840\u6db2\u306e\u4e2d\u306e\u30ab\u30ea\u30a6\u30e0\u304c\u5897\u3048\u308b\u3053\u3068\u304c\u3042\u308b\u305f\u3081\u3001\u30ab\u30ea\u30a6\u30e0\u3092\u542b\u3080\u5869\u306e\u4ee3\u308f\u308a\u306e\u8abf\u5473\u6599(\u6e1b\u5869\u3057\u304a\u306a\u3069)\u3092\u4f7f\u3046\u3068\u304d\u306f\u304a\u533b\u8005\u3055\u3093\u306b\u76f8\u8ac7\u304c\u5fc5\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u5229\u5c3f\u85ac\u306f\u4f53\u306e\u4f59\u5206\u306a\u6c34\u5206\u3068\u5869\u5206\u3092\u6392\u51fa\u3057\u3066\u8840\u5727\u3092\u4e0b\u3052\u308b<\/h3>\n\n\n\n<p><span class=\"swl-marker mark_orange\"><strong>\u5229\u5c3f\u85ac\u306f\u3001\u814e\u81d3\u306b\u50cd\u304d\u304b\u3051\u3066\u5c3f\u306e\u91cf\u3092\u5897\u3084\u3057\u3001\u4f53\u306e\u4e2d\u306e\u4f59\u5206\u306a\u6c34\u5206\u3068\u5869\u5206\u3092\u5916\u306b\u51fa\u3059\u3053\u3068\u3067\u8840\u5727\u3092\u4e0b\u3052\u308b\u85ac<\/strong><\/span>\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u5358\u72ec\u3067\u4f7f\u308f\u308c\u308b\u3053\u3068\u3082\u3042\u308a\u307e\u3059\u304c\u3001\u4ed6\u306e\u964d\u5727\u85ac\u3068\u7d44\u307f\u5408\u308f\u305b\u3066\u4f7f\u308f\u308c\u308b\u3053\u3068\u304c\u591a\u304f\u3001\u4e00\u7dd2\u306b\u4f7f\u3046\u3053\u3068\u3067\u8840\u5727\u3092\u4e0b\u3052\u308b\u52b9\u679c\u304c\u3050\u3063\u3068\u9ad8\u307e\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"has-text-align-center u-mb-ctrl u-mb-0\">\u5229\u5c3f\u85ac\u306e\u4e3b\u306a\u30bf\u30a4\u30d7<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><thead><tr><th>\u30bf\u30a4\u30d7<\/th><th>\u4ee3\u8868\u7684\u306a\u85ac<\/th><th>\u7279\u5fb4<\/th><\/tr><\/thead><tbody><tr><td>\u30b5\u30a4\u30a2\u30b6\u30a4\u30c9\u7cfb\u5229\u5c3f\u85ac<\/td><td>\u30d2\u30c9\u30ed\u30af\u30ed\u30ed\u30c1\u30a2\u30b8\u30c9\u3001\u30c8\u30ea\u30af\u30ed\u30eb\u30e1\u30c1\u30a2\u30b8\u30c9<\/td><td>\u814e\u81d3\u306e\u9060\u4f4d\u5c3f\u7d30\u7ba1\u3067\u5869\u5206\u306e\u518d\u5438\u53ce\u3092\u6291\u3048\u308b\u3002\u6700\u3082\u4e00\u822c\u7684\u306b\u4f7f\u308f\u308c\u308b<\/td><\/tr><tr><td>\u30eb\u30fc\u30d7\u5229\u5c3f\u85ac<\/td><td>\u30d5\u30ed\u30bb\u30df\u30c9<\/td><td>\u3088\u308a\u5f37\u529b\u306a\u5229\u5c3f\u4f5c\u7528\u3002\u814e\u6a5f\u80fd\u304c\u4f4e\u4e0b\u3057\u3066\u3044\u308b\u65b9\u306b\u3082\u4f7f\u3048\u308b<\/td><\/tr><tr><td>\u30ab\u30ea\u30a6\u30e0\u4fdd\u6301\u6027\u5229\u5c3f\u85ac<\/td><td>\u30b9\u30d4\u30ed\u30ce\u30e9\u30af\u30c8\u30f3<\/td><td>\u30ab\u30ea\u30a6\u30e0\u304c\u6e1b\u308a\u306b\u304f\u3044\u3002MR\u62ee\u6297\u85ac\u3068\u3057\u3066\u7279\u6b8a\u306a\u7528\u9014\u306b\u3082\u4f7f\u308f\u308c\u308b<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p>\u5229\u5c3f\u85ac\u306b\u306f\u4e3b\u306b\u300c<span class=\"swl-marker mark_orange\"><strong>\u30b5\u30a4\u30a2\u30b6\u30a4\u30c9\u7cfb\u5229\u5c3f\u85ac<\/strong><\/span>\u300d\u3068\u300c<span class=\"swl-marker mark_orange\"><strong>\u30eb\u30fc\u30d7\u5229\u5c3f\u85ac<\/strong><\/span>\u300d\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u30b5\u30a4\u30a2\u30b6\u30a4\u30c9\u7cfb\u5229\u5c3f\u85ac(\u30d2\u30c9\u30ed\u30af\u30ed\u30ed\u30c1\u30a2\u30b8\u30c9\u3001\u30c8\u30ea\u30af\u30ed\u30eb\u30e1\u30c1\u30a2\u30b8\u30c9\u306a\u3069)\u306f\u3001\u814e\u81d3\u306e\u7279\u5b9a\u306e\u90e8\u5206(\u9060\u4f4d\u5c3f\u7d30\u7ba1)\u3067\u5869\u5206\u304c\u4f53\u306b\u518d\u5438\u53ce\u3055\u308c\u308b\u306e\u3092\u6291\u3048\u3001\u5869\u5206\u3068\u6c34\u5206\u3092\u5c3f\u3068\u3057\u3066\u5916\u306b\u51fa\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u30eb\u30fc\u30d7\u5229\u5c3f\u85ac(\u30d5\u30ed\u30bb\u30df\u30c9\u306a\u3069)\u306f\u3001\u3088\u308a\u5f37\u529b\u306b\u5c3f\u3092\u51fa\u3055\u305b\u308b\u50cd\u304d\u3092\u6301\u3061\u3001\u814e\u81d3\u306e\u50cd\u304d\u304c\u843d\u3061\u3066\u3044\u308b\u65b9\u306b\u3082\u52b9\u679c\u304c\u671f\u5f85\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<p><a href=\"https:\/\/jamanetwork.com\/journals\/jama\/fullarticle\/195626\">\u30a2\u30e1\u30ea\u30ab\u306e\u56fd\u7acb\u5fc3\u80ba\u8840\u6db2\u7814\u7a76\u6240\u304c\u884c\u3063\u305f\u5927\u304d\u306a\u81e8\u5e8a\u8a66\u9a13<\/a>\u3067\u306f\u3001<span class=\"swl-marker mark_orange\"><strong>\u30b5\u30a4\u30a2\u30b6\u30a4\u30c9\u7cfb\u5229\u5c3f\u85ac\u306e\u4e00\u7a2e\u3067\u3042\u308b\u30af\u30ed\u30eb\u30bf\u30ea\u30c9\u30f3\u304c\u3001\u5fc3\u81d3\u3084\u8840\u7ba1\u306e\u75c5\u6c17\u3092\u9632\u3050\u52b9\u679c\u304c\u4ed6\u306e\u964d\u5727\u85ac\u3068\u540c\u3058\u304b\u305d\u308c\u4ee5\u4e0a\u3067\u3001\u3057\u304b\u3082\u5024\u6bb5\u3082\u5b89\u3044<\/strong><\/span>\u3053\u3068\u304c\u308f\u304b\u308a\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u3053\u306e\u305f\u3081\u3001\u65e5\u672c\u306e\u9ad8\u8840\u5727\u6cbb\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u3067\u3082\u3001\u6700\u521d\u306b\u4f7f\u3046\u3079\u304d\u85ac\u306e\u4e00\u3064\u3068\u3057\u3066\u63a8\u5968\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"swell-block-capbox cap_box is-style-onborder_ttl\"><div class=\"cap_box_ttl\"><span>\u3088\u304f\u3042\u308b\u526f\u4f5c\u7528<\/span><\/div><div class=\"cap_box_content\">\n<ul class=\"wp-block-list\">\n<li>\u4f4e\u30ab\u30ea\u30a6\u30e0\u8840\u75c7(\u4f53\u304c\u3060\u308b\u3044\u3001\u529b\u304c\u5165\u3089\u306a\u3044\u3001\u7b4b\u8089\u304c\u3064\u308b)<\/li>\n\n\n\n<li>\u4f4e\u30ca\u30c8\u30ea\u30a6\u30e0\u8840\u75c7<\/li>\n\n\n\n<li>\u5c3f\u9178\u5024\u306e\u4e0a\u6607(\u75db\u98a8\u306e\u30ea\u30b9\u30af)<\/li>\n\n\n\n<li>\u8840\u7cd6\u5024\u306e\u4e0a\u6607<\/li>\n\n\n\n<li>\u307e\u308c\u306b\u5149\u7dda\u904e\u654f\u75c7\u3084\u767a\u75b9<\/li>\n<\/ul>\n<\/div><\/div>\n\n\n\n<p>\u5229\u5c3f\u85ac\u306e\u526f\u4f5c\u7528\u3067\u6ce8\u610f\u304c\u5fc5\u8981\u306a\u306e\u306f\u3001\u4f53\u306e\u4e2d\u306e\u30df\u30cd\u30e9\u30eb\u306e\u30d0\u30e9\u30f3\u30b9\u304c\u5d29\u308c\u308b\u3053\u3068\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u7279\u306b<span class=\"swl-marker mark_orange\"><strong>\u4f4e\u30ab\u30ea\u30a6\u30e0\u8840\u75c7 (\u8840\u6db2\u306e\u4e2d\u306e\u30ab\u30ea\u30a6\u30e0\u304c\u6e1b\u308b\u72b6\u614b)\u3084\u4f4e\u30ca\u30c8\u30ea\u30a6\u30e0\u8840\u75c7<\/strong><\/span>\u304c\u8d77\u3053\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u30ab\u30ea\u30a6\u30e0\u304c\u8db3\u308a\u306a\u304f\u306a\u308b\u3068\u3001\u4f53\u306b\u529b\u304c\u5165\u3089\u306a\u3044\u3001\u7b4b\u8089\u304c\u3064\u308b\u3001\u8108\u306e\u30ea\u30ba\u30e0\u304c\u4e71\u308c\u308b\u306a\u3069\u304c\u8d77\u3053\u308b\u3053\u3068\u304c\u3042\u308b\u305f\u3081\u3001\u5b9a\u671f\u7684\u306a\u8840\u6db2\u691c\u67fb\u304c\u5fc5\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u305d\u306e\u4ed6\u3001<span class=\"swl-marker mark_orange\"><strong>\u5c3f\u9178\u5024\u304c\u4e0a\u304c\u3063\u3066\u75db\u98a8\u306e\u767a\u4f5c\u304c\u8d77\u3053\u308a\u3084\u3059\u304f\u306a\u3063\u305f\u308a\u3001\u8840\u7cd6\u5024\u304c\u5c11\u3057\u4e0a\u304c\u3063\u305f\u308a\u3059\u308b<\/strong><\/span>\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p>\u3053\u308c\u3089\u306e\u526f\u4f5c\u7528\u306e\u307b\u3068\u3093\u3069\u306f\u5229\u5c3f\u85ac\u306e\u6295\u4e0e\u91cf\u306b\u76f4\u63a5\u95a2\u9023\u3057\u3066\u304a\u308a\u3001\u4f4e\u30ab\u30ea\u30a6\u30e0\u8840\u75c7\u3068\u4f4e\u30ca\u30c8\u30ea\u30a6\u30e0\u8840\u75c7\u304c\u6700\u3082\u591a\u304f\u307f\u3089\u308c\u308b\u4ee3\u8b1d\u4f5c\u7528\u3067\u3042\u308a\u3001\u6b21\u3044\u3067\u9ad8\u5c3f\u9178\u8840\u75c7\u3001\u4f4e\u30de\u30b0\u30cd\u30b7\u30a6\u30e0\u8840\u75c7\u3001\u9ad8\u8102\u8840\u75c7\u3001\u8840\u7cd6\u5024\u306e\u4e0a\u6607\u304c\u7d9a\u304f\u3002<\/p>\n<cite>\u5f15\u7528\uff1aNational Center for Biotechnology Information <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK554579\/\">Antihypertensive Medications<\/a><\/cite><\/blockquote>\n\n\n\n<p>\u307e\u305f\u3001\u307e\u308c\u306b\u65e5\u5149\u306b\u5f53\u305f\u308b\u3068\u76ae\u819a\u306b\u767a\u75b9\u304c\u51fa\u308b(\u5149\u7dda\u904e\u654f\u75c7)\u3053\u3068\u3084\u3001\u767a\u75b9\u304c\u51fa\u308b\u3053\u3068\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u5229\u5c3f\u85ac\u3092\u98f2\u3080\u3068\u304d\u306f\u3001\u8131\u6c34\u306b\u6ce8\u610f\u304c\u5fc5\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u7279\u306b\u4ee5\u4e0b\u306e\u3088\u3046\u306a\u72b6\u6cc1\u3067\u306f\u3001\u4e00\u6642\u7684\u306b\u85ac\u3092\u6b62\u3081\u305f\u65b9\u304c\u3044\u3044\u304b\u3069\u3046\u304b\u304a\u533b\u8005\u3055\u3093\u306b\u76f8\u8ac7\u3057\u307e\u3057\u3087\u3046\u3002<\/p>\n\n\n\n<div class=\"swell-block-capbox cap_box is-style-onborder_ttl\"><div class=\"cap_box_ttl\"><span>\u6ce8\u610f\u304c\u5fc5\u8981\u306a\u72b6\u6cc1<\/span><\/div><div class=\"cap_box_content\">\n<ul class=\"wp-block-list\">\n<li>\u3072\u3069\u3044\u4e0b\u75e2\u3084\u5614\u5410\u304c\u3042\u308b\u3068\u304d<\/li>\n\n\n\n<li>\u305f\u304f\u3055\u3093\u6c57\u3092\u304b\u3044\u305f\u3068\u304d<\/li>\n\n\n\n<li>\u767a\u71b1\u304c\u7d9a\u3044\u3066\u3044\u308b\u3068\u304d<\/li>\n<\/ul>\n<\/div><\/div>\n\n\n\n<h3 class=\"wp-block-heading\">\u03b2\u906e\u65ad\u85ac\u306f\u5fc3\u62cd\u6570\u3092\u6291\u3048\u3066\u5fc3\u81d3\u306e\u8ca0\u62c5\u3092\u6e1b\u3089\u3059\u964d\u5727\u85ac<\/h3>\n\n\n\n<p><span class=\"swl-marker mark_orange\"><strong>\u03b2\u906e\u65ad\u85ac(\u30d9\u30fc\u30bf\u3057\u3083\u3060\u3093\u3084\u304f)\u306f\u3001\u5fc3\u81d3\u306e\u62cd\u52d5\u3092\u8abf\u6574\u3059\u308b\u4ea4\u611f\u795e\u7d4c\u7cfb\u306e\u50cd\u304d\u3092\u6291\u3048\u308b\u3053\u3068\u3067\u3001\u5fc3\u81d3\u306e\u62cd\u52d5\u56de\u6570\u3092\u6e1b\u3089\u3057\u3001\u5fc3\u81d3\u306e\u53ce\u7e2e\u3059\u308b\u529b\u3092\u5f31\u3081\u3066\u8840\u5727\u3092\u4e0b\u3052\u308b\u85ac<\/strong><\/span>\u3067\u3059\u3002<\/p>\n\n\n\n<div class=\"swell-block-capbox cap_box is-style-onborder_ttl\"><div class=\"cap_box_ttl\"><span>\u4ee3\u8868\u7684\u306a\u85ac<\/span><\/div><div class=\"cap_box_content\">\n<ul class=\"wp-block-list\">\n<li>\u30a2\u30c6\u30ce\u30ed\u30fc\u30eb<\/li>\n\n\n\n<li>\u30e1\u30c8\u30d7\u30ed\u30ed\u30fc\u30eb<\/li>\n\n\n\n<li>\u30ab\u30eb\u30d9\u30b8\u30ed\u30fc\u30eb<\/li>\n\n\n\n<li>\u30d3\u30bd\u30d7\u30ed\u30ed\u30fc\u30eb<\/li>\n\n\n\n<li>\u30cd\u30d3\u30dc\u30ed\u30fc\u30eb<\/li>\n<\/ul>\n<\/div><\/div>\n\n\n\n<p>\u3053\u306e\u85ac\u306f\u5fc3\u81d3\u306e\u300c\u03b2\u53d7\u5bb9\u4f53\u300d\u3068\u3044\u3046\u90e8\u5206\u3092\u30d6\u30ed\u30c3\u30af\u3059\u308b\u3053\u3068\u3067\u52b9\u679c\u3092\u767a\u63ee\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p><span class=\"swl-marker mark_orange\"><strong>\u4ea4\u611f\u795e\u7d4c\u304c\u8208\u596e\u3059\u308b\u3068\u3001\u30ce\u30eb\u30a2\u30c9\u30ec\u30ca\u30ea\u30f3\u3068\u3044\u3046\u7269\u8cea\u304c\u5fc3\u81d3\u306e\u03b2\u53d7\u5bb9\u4f53\u306b\u7d50\u5408\u3057\u3066\u5fc3\u81d3\u306e\u62cd\u52d5\u3092\u901f\u304f\u3057\u305f\u308a\u5f37\u304f\u3057\u305f\u308a\u3057\u307e\u3059\u304c\u3001\u03b2\u906e\u65ad\u85ac\u306f\u3053\u306e\u7d50\u5408\u3092\u9632\u304e\u307e\u3059\u3002<\/strong><\/span><\/p>\n\n\n\n<p>\u305d\u306e\u7d50\u679c\u3001\u5fc3\u81d3\u304c\u3086\u3063\u304f\u308a\u3068\u3001\u3088\u308a\u5f31\u3044\u529b\u3067\u62cd\u52d5\u3059\u308b\u3088\u3046\u306b\u306a\u308a\u3001\u5fc3\u81d3\u306e\u8ca0\u62c5\u304c\u8efd\u304f\u306a\u3063\u3066\u8840\u5727\u304c\u4e0b\u304c\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"swell-block-capbox cap_box is-style-onborder_ttl\"><div class=\"cap_box_ttl\"><span>\u03b2\u906e\u65ad\u85ac\u304c\u7279\u306b\u4f7f\u308f\u308c\u308b\u5834\u5408<\/span><\/div><div class=\"cap_box_content\">\n<ul class=\"wp-block-list\">\n<li>\u5fc3\u7b4b\u6897\u585e\u3092\u8d77\u3053\u3057\u305f\u5f8c<\/li>\n\n\n\n<li>\u5fc3\u4e0d\u5168<\/li>\n\n\n\n<li>\u8108\u304c\u901f\u304f\u306a\u308b\u4e0d\u6574\u8108<\/li>\n\n\n\n<li>\u72ed\u5fc3\u75c7<\/li>\n\n\n\n<li>\u82e5\u3044\u65b9\u3067\u8108\u304c\u901f\u3044\u9ad8\u8840\u5727<\/li>\n<\/ul>\n<\/div><\/div>\n\n\n\n<p>\u03b2\u906e\u65ad\u85ac\u306f\u3001\u9ad8\u8840\u5727\u4ee5\u5916\u306b\u3082<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC2249618\/\">\u5fc3\u7b4b\u6897\u585e\u3092\u8d77\u3053\u3057\u305f\u5f8c\u306e\u65b9\u3001\u5fc3\u4e0d\u5168\u306e\u65b9<\/a>\u3001\u8108\u304c\u901f\u304f\u306a\u308b\u4e0d\u6574\u8108\u304c\u3042\u308b\u65b9\u3001\u72ed\u5fc3\u75c7\u306e\u65b9\u306a\u3069\u306e\u6cbb\u7642\u306b\u3082\u4f7f\u308f\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u82e5\u3044\u65b9\u306e\u9ad8\u8840\u5727\u3084\u3001\u8108\u304c\u901f\u3044\u65b9\u306b\u7279\u306b\u52b9\u679c\u7684\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u305f\u3060\u3057\u3001\u65e5\u672c\u306e\u9ad8\u8840\u5727\u6cbb\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u3067\u306f\u3001<span class=\"swl-marker mark_orange\"><strong>\u03b2\u906e\u65ad\u85ac\u306f\u5358\u72ec\u3067\u6700\u521d\u306b\u4f7f\u3046\u85ac\u3068\u3057\u3066\u306f\u63a8\u5968\u3055\u308c\u3066\u3044\u307e\u305b\u3093<\/strong><\/span>\u3002<\/p>\n\n\n\n<p>\u3053\u308c\u306f\u3001\u7cd6\u5c3f\u75c5\u306b\u306a\u308a\u3084\u3059\u304f\u306a\u308b\u30ea\u30b9\u30af\u304c\u3042\u308b\u3053\u3068\u3084\u3001\u4ed6\u306e\u964d\u5727\u85ac\u3068\u6bd4\u3079\u3066\u8133\u5352\u4e2d\u3084\u5fc3\u81d3\u306e\u75c5\u6c17\u3092\u9632\u3050\u52b9\u679c\u304c\u3084\u3084\u52a3\u308b\u3068\u3044\u3046\u7814\u7a76\u7d50\u679c\u304c\u3042\u308b\u305f\u3081\u3067\u3059\u3002<\/p>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p>\u30d9\u30fc\u30bf\u906e\u65ad\u85ac\u306f\u3001\u65b0\u898f\u767a\u75c7DM\u306e\u30ea\u30b9\u30af\u5897\u52a0\u3068\u95a2\u9023\u3057\u3066\u304a\u308a\u3001\u6b7b\u4ea1\u307e\u305f\u306f\u5fc3\u7b4b\u6897\u585e\u306e\u30a8\u30f3\u30c9\u30dd\u30a4\u30f3\u30c8\u306b\u306f\u5229\u70b9\u304c\u306a\u304f\u3001\u4ed6\u306e\u85ac\u5264\u3068\u6bd4\u8f03\u3057\u3066\u8133\u5352\u4e2d\u306e\u30ea\u30b9\u30af\u309215\uff05\u5897\u52a0\u3055\u305b\u307e\u3059\u3002<\/p>\n<cite>\u5f15\u7528\uff1aPubMed <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17920367\/\">A meta-analysis of 94,492 patients with hypertension treated with beta blockers to determine the risk of new-onset diabetes mellitus<\/a><\/cite><\/blockquote>\n\n\n\n<p>\u5fc3\u81d3\u306e\u75c5\u6c17\u304c\u3042\u308b\u5834\u5408\u3092\u9664\u3044\u3066\u3001\u901a\u5e38\u306f\u4ed6\u306e\u964d\u5727\u85ac\u3068\u7d44\u307f\u5408\u308f\u305b\u3066\u4f7f\u308f\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"swell-block-capbox cap_box is-style-onborder_ttl\"><div class=\"cap_box_ttl\"><span>\u3088\u304f\u3042\u308b\u526f\u4f5c\u7528<\/span><\/div><div class=\"cap_box_content\">\n<ul class=\"wp-block-list\">\n<li>\u4f53\u306e\u3060\u308b\u3055\u3001\u75b2\u308c\u3084\u3059\u3055<\/li>\n\n\n\n<li>\u5f90\u8108(\u8108\u304c\u9045\u304f\u306a\u308b)<\/li>\n\n\n\n<li>\u624b\u8db3\u306e\u51b7\u3048<\/li>\n\n\n\n<li>\u6c17\u7ba1\u652f\u53ce\u7e2e(\u5598\u606f\u3084COPD\u306e\u65b9\u306f\u6ce8\u610f\u304c\u5fc5\u8981)<\/li>\n<\/ul>\n<\/div><\/div>\n\n\n\n<p>\u03b2\u906e\u65ad\u85ac\u306e\u526f\u4f5c\u7528\u3068\u3057\u3066\u3001<a href=\"https:\/\/www.nhs.uk\/medicines\/beta-blockers\/\">\u4f53\u304c\u3060\u308b\u3044\u3001\u75b2\u308c\u3084\u3059\u3044\u3001\u624b\u8db3\u304c\u51b7\u305f\u3044<\/a>\u306a\u3069\u304c\u73fe\u308c\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u307e\u305f\u3001\u8108\u304c\u9045\u304f\u306a\u308a\u3059\u304e\u308b\u3053\u3068\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u5598\u606f\u3084\u6162\u6027\u9589\u585e\u6027\u80ba\u75be\u60a3(COPD\u3001\u80ba\u6c17\u816b\u306a\u3069)\u304c\u3042\u308b\u65b9\u306f\u3001\u6c17\u7ba1\u652f\u304c\u7e2e\u3093\u3067\u547c\u5438\u304c\u82e6\u3057\u304f\u306a\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u305f\u3081\u3001\u539f\u5247\u3068\u3057\u3066\u4f7f\u7528\u3092\u907f\u3051\u307e\u3059\u304c\u3001<a href=\"https:\/\/bpac.org.nz\/2024\/beta-blockers.aspx\">\u75c5\u72b6\u306b\u3088\u308a\u614e\u91cd\u306b\u4f7f\u308f\u308c\u308b\u3053\u3068\u3082\u3042\u308a\u307e\u3059<\/a>\u3002<\/p>\n\n\n\n<p class=\"is-style-balloon_box\">\u975e\u5e38\u306b\u91cd\u8981\u306a\u6ce8\u610f\u70b9<\/p>\n\n\n\n<p>\u5927\u5207\u306a\u6ce8\u610f\u70b9\u3068\u3057\u3066\u3001 \u03b2\u906e\u65ad\u85ac\u3092\u6025\u306b\u3084\u3081\u308b\u3068\u3001<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC7155970\/\">\u8840\u5727\u304c\u6025\u306b\u4e0a\u304c\u3063\u305f\u308a\u3001\u72ed\u5fc3\u75c7\u306e\u767a\u4f5c\u304c\u8d77\u3053\u3063\u305f\u308a\u3059\u308b\u5371\u967a<\/a>\u304c\u3042\u308a\u307e\u3059 \u3002<\/p>\n\n\n\n<p>\u5fc5\u305a\u304a\u533b\u8005\u3055\u3093\u306e\u6307\u793a\u306b\u5f93\u3063\u3066\u3001\u5c11\u3057\u305a\u3064\u91cf\u3092\u6e1b\u3089\u3057\u306a\u304c\u3089\u3084\u3081\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u03b1\u906e\u65ad\u85ac\u306a\u3069\u305d\u306e\u4ed6\u306e\u964d\u5727\u85ac\u306e\u7279\u5fb4<\/h3>\n\n\n\n<p><span class=\"swl-marker mark_orange\"><strong>\u03b1\u906e\u65ad\u85ac(\u30a2\u30eb\u30d5\u30a1\u3057\u3083\u3060\u3093\u3084\u304f)\u306f\u3001\u8840\u7ba1\u306b\u3042\u308b\u300c\u03b1\u53d7\u5bb9\u4f53\u300d\u3092\u30d6\u30ed\u30c3\u30af\u3059\u308b\u3053\u3068\u3067\u8840\u7ba1\u3092\u5e83\u3052\u3001\u8840\u5727\u3092\u4e0b\u3052\u308b\u85ac<\/strong><\/span>\u3067\u3059\u3002<\/p>\n\n\n\n<div class=\"swell-block-capbox cap_box is-style-onborder_ttl\"><div class=\"cap_box_ttl\"><span>\u4ee3\u8868\u7684\u306a\u85ac<\/span><\/div><div class=\"cap_box_content\">\n<ul class=\"wp-block-list\">\n<li>\u30c9\u30ad\u30b5\u30be\u30b7\u30f3<\/li>\n\n\n\n<li>\u30d7\u30e9\u30be\u30b7\u30f3<\/li>\n\n\n\n<li>\u30c6\u30e9\u30be\u30b7\u30f3<\/li>\n<\/ul>\n<\/div><\/div>\n\n\n\n<p>\u03b1\u906e\u65ad\u85ac\u306f\u3001\u8910\u8272\u7d30\u80de\u816b(\u526f\u814e\u3068\u3044\u3046\u81d3\u5668\u306b\u3067\u304d\u308b\u816b\u760d\u3067\u3001\u8840\u5727\u3092\u4e0a\u3052\u308b\u30db\u30eb\u30e2\u30f3\u3092\u305f\u304f\u3055\u3093\u51fa\u3059\u75c5\u6c17)\u306b\u3088\u308b\u9ad8\u8840\u5727\u306e\u6cbb\u7642\u306b\u4f7f\u308f\u308c\u308b\u307b\u304b\u3001<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC8108949\/\">\u524d\u7acb\u817a\u80a5\u5927\u75c7<\/a>\u3067\u304a\u3057\u3063\u3053\u304c\u51fa\u306b\u304f\u3044\u75c7\u72b6\u304c\u3042\u308b\u7537\u6027\u306e\u65b9\u306b\u51e6\u65b9\u3055\u308c\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"swell-block-capbox cap_box is-style-onborder_ttl\"><div class=\"cap_box_ttl\"><span>\u03b1\u906e\u65ad\u85ac\u306e\u4e3b\u306a\u526f\u4f5c\u7528<\/span><\/div><div class=\"cap_box_content\">\n<ul class=\"wp-block-list\">\n<li>\u8d77\u7acb\u6027\u4f4e\u8840\u5727(\u7acb\u3061\u4e0a\u304c\u3063\u305f\u3068\u304d\u306b\u8840\u5727\u304c\u4e0b\u304c\u308a\u3059\u304e\u308b)<\/li>\n\n\n\n<li>\u3081\u307e\u3044\u3001\u3075\u3089\u3064\u304d<\/li>\n\n\n\n<li>\u521d\u56de\u6295\u4e0e\u6642\u306e\u5931\u795e<\/li>\n<\/ul>\n<\/div><\/div>\n\n\n\n<p>\u03b1\u906e\u65ad\u85ac\u306e\u526f\u4f5c\u7528\u3067\u6ce8\u610f\u304c\u5fc5\u8981\u306a\u306e\u306f\u3001<a href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2021\/019668Orig1s032lbl.pdf\">\u8d77\u7acb\u6027\u4f4e\u8840\u5727(\u7acb\u3061\u4e0a\u304c\u3063\u305f\u3068\u304d\u306b\u8840\u5727\u304c\u4e0b\u304c\u308a\u3059\u304e\u308b\u72b6\u614b)<\/a>\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u7279\u306b<span class=\"swl-marker mark_orange\"><strong>\u521d\u3081\u3066\u98f2\u3080\u3068\u304d\u3084\u3001\u91cf\u3092\u5897\u3084\u3057\u305f\u3068\u304d\u306b\u3001\u3081\u307e\u3044\u3001\u3075\u3089\u3064\u304d\u3001\u3068\u304d\u306b\u306f\u6c17\u3092\u5931\u3046<\/strong><\/span>\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3053\u306e\u305f\u3081\u3001\u5c11\u306a\u3044\u91cf\u304b\u3089\u59cb\u3081\u3066\u5f90\u3005\u306b\u5897\u3084\u3059\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"has-text-align-center u-mb-ctrl u-mb-0\">\u305d\u306e\u4ed6\u306e\u964d\u5727\u85ac<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><thead><tr><th>\u85ac\u306e\u30bf\u30a4\u30d7<\/th><th>\u4e3b\u306a\u7528\u9014<\/th><th>\u7279\u5fb4<\/th><\/tr><\/thead><tbody><tr><td>\u4e2d\u67a2\u6027\u4ea4\u611f\u795e\u7d4c\u6291\u5236\u85ac<\/td><td>\u6cbb\u7642\u62b5\u6297\u6027\u9ad8\u8840\u5727<\/td><td>\u8133\u306e\u8840\u5727\u8abf\u6574\u4e2d\u67a2\u306b\u4f5c\u7528\u3002<a href=\"https:\/\/www.ahajournals.org\/doi\/10.1161\/cir.0000000000000597\">\u6025\u306a\u4e2d\u6b62\u306f\u5371\u967a<\/a><\/td><\/tr><tr><td>MR\u62ee\u6297\u85ac(\u30df\u30cd\u30e9\u30eb\u30b3\u30eb\u30c1\u30b3\u30a4\u30c9\u53d7\u5bb9\u4f53\u62ee\u6297\u85ac)<\/td><td>\u6cbb\u7642\u62b5\u6297\u6027\u9ad8\u8840\u5727\u3001\u539f\u767a\u6027\u30a2\u30eb\u30c9\u30b9\u30c6\u30ed\u30f3\u75c7<\/td><td>\u5869\u5206\u3092\u4f53\u306b\u305f\u3081\u3053\u3080\u30db\u30eb\u30e2\u30f3\u306e\u50cd\u304d\u3092\u6291\u3048\u308b<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p>\u305d\u306e\u4ed6\u306e\u964d\u5727\u85ac\u3068\u3057\u3066\u3001\u4e2d\u67a2\u6027\u4ea4\u611f\u795e\u7d4c\u6291\u5236\u85ac\u3084\u30df\u30cd\u30e9\u30eb\u30b3\u30eb\u30c1\u30b3\u30a4\u30c9\u53d7\u5bb9\u4f53\u62ee\u6297\u85ac(MR\u62ee\u6297\u85ac)\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p><span class=\"swl-marker mark_orange\"><strong>\u4e2d\u67a2\u6027\u4ea4\u611f\u795e\u7d4c\u6291\u5236\u85ac<\/strong><\/span>\u306f\u3001\u8133\u306e\u8840\u5727\u3092\u8abf\u6574\u3059\u308b\u90e8\u5206\u306b\u50cd\u3044\u3066\u4ea4\u611f\u795e\u7d4c\u306e\u50cd\u304d\u3092\u6291\u3048\u3001\u8840\u5727\u3092\u4e0b\u3052\u307e\u3059\u3002<\/p>\n\n\n\n<p><span class=\"swl-marker mark_orange\"><strong>MR\u62ee\u6297\u85ac<\/strong><\/span>\u306f\u3001\u30a2\u30eb\u30c9\u30b9\u30c6\u30ed\u30f3\u3068\u3044\u3046\u5869\u5206\u3092\u4f53\u306b\u305f\u3081\u3053\u3080\u30db\u30eb\u30e2\u30f3\u306e\u50cd\u304d\u3092\u6291\u3048\u308b\u85ac\u3067\u3001\u3044\u304f\u3064\u304b\u306e\u964d\u5727\u85ac\u3092\u4f7f\u3063\u3066\u3082\u8840\u5727\u304c\u5341\u5206\u306b\u4e0b\u304c\u3089\u306a\u3044\u65b9(\u6cbb\u7642\u62b5\u6297\u6027\u9ad8\u8840\u5727)\u3084\u3001\u539f\u767a\u6027\u30a2\u30eb\u30c9\u30b9\u30c6\u30ed\u30f3\u75c7\u3068\u3044\u3046\u75c5\u6c17\u306e\u6cbb\u7642\u306b\u4f7f\u308f\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3053\u308c\u3089\u306e\u85ac\u306f\u6700\u521d\u306b\u9078\u3070\u308c\u308b\u85ac\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u304c\u3001\u7279\u5b9a\u306e\u75c5\u6c17\u3082\u4e00\u7dd2\u306b\u6301\u3063\u3066\u3044\u308b\u5834\u5408\u3084\u3001\u4ed6\u306e\u85ac\u3067\u306f\u5341\u5206\u306b\u52b9\u679c\u304c\u5f97\u3089\u308c\u306a\u304b\u3063\u305f\u5834\u5408\u306b\u5927\u5207\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u5e74\u9f62\u3084\u6301\u75c5\u306b\u3088\u3063\u3066\u9069\u3057\u305f\u964d\u5727\u85ac\u306f\u7570\u306a\u308b<\/h2>\n\n\n\n<p>\u964d\u5727\u85ac\u3092\u9078\u3076\u3068\u304d\u306f\u3001\u305f\u3060\u8840\u5727\u3092\u4e0b\u3052\u308b\u3060\u3051\u3067\u306a\u304f\u3001\u60a3\u8005\u3055\u3093\u306e\u5e74\u9f62\u3001\u4ed6\u306b\u304b\u304b\u3063\u3066\u3044\u308b\u75c5\u6c17\u3001\u305d\u306e\u4ed6\u306e\u5065\u5eb7\u72b6\u614b\u306a\u3069\u3092\u7dcf\u5408\u7684\u306b\u898b\u3066\u6c7a\u3081\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u540c\u3058\u9ad8\u8840\u5727\u3067\u3082\u3001\u82e5\u3044\u65b9\u3068\u9ad8\u9f62\u8005\u3067\u306f\u3001\u307e\u305f\u7cd6\u5c3f\u75c5\u3084\u814e\u81d3\u75c5\u304c\u3042\u308b\u65b9\u3068\u306a\u3044\u65b9\u3067\u306f\u3001\u6700\u3082\u5408\u3046\u85ac\u304c\u9055\u3046\u306e\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u3053\u308c\u306f\u3001\u9ad8\u8840\u5727\u306b\u306a\u308b\u4ed5\u7d44\u307f\u304c\u4eba\u306b\u3088\u3063\u3066\u9055\u3046\u3053\u3068\u3084\u3001\u5e74\u9f62\u3084\u6301\u75c5\u306b\u3088\u3063\u3066\u85ac\u306e\u52b9\u304d\u65b9\u3084\u526f\u4f5c\u7528\u306e\u51fa\u3084\u3059\u3055\u304c\u5909\u308f\u308b\u305f\u3081\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u305f\u3068\u3048\u3070\u3001<span class=\"swl-marker mark_orange\"><strong>\u82e5\u3044\u65b9\u306e\u9ad8\u8840\u5727\u306f\u4f53\u306e\u4e2d\u306e\u8840\u5727\u3092\u8abf\u6574\u3059\u308b\u30b7\u30b9\u30c6\u30e0\u304c\u50cd\u304d\u3059\u304e\u3066\u3044\u308b\u3053\u3068\u304c\u539f\u56e0\u306e\u3053\u3068\u304c\u591a\u304f\u3001\u9ad8\u9f62\u8005\u306e\u9ad8\u8840\u5727\u306f\u8840\u7ba1\u304c\u786c\u304f\u306a\u3063\u3066\u3044\u308b\u3053\u3068\u304c\u4e3b\u306a\u539f\u56e0\u306e\u3053\u3068\u304c\u591a\u3044<\/strong><\/span>\u305f\u3081\u3001\u305d\u308c\u305e\u308c\u306b\u5408\u3063\u305f\u85ac\u304c\u9078\u3070\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u307e\u305f\u3001\u7cd6\u5c3f\u75c5\u3084\u814e\u81d3\u75c5\u3001\u5fc3\u81d3\u75c5\u306a\u3069\u3082\u4e00\u7dd2\u306b\u304b\u304b\u3063\u3066\u3044\u308b\u5834\u5408\u306b\u306f\u3001\u8840\u5727\u3092\u4e0b\u3052\u308b\u3060\u3051\u3067\u306a\u304f\u3001\u3053\u308c\u3089\u306e\u81d3\u5668\u3092\u5b88\u308b\u52b9\u679c\u3082\u671f\u5f85\u3067\u304d\u308b\u964d\u5727\u85ac\u304c\u9078\u3070\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3053\u306e\u3088\u3046\u306b\u3001\u4e00\u4eba\u3072\u3068\u308a\u306e\u72b6\u614b\u306b\u5408\u308f\u305b\u3066\u6700\u9069\u306a\u85ac\u3092\u9078\u3076\u3053\u3068\u304c\u3001\u9ad8\u8840\u5727\u6cbb\u7642\u3092\u3046\u307e\u304f\u9032\u3081\u308b\u30b3\u30c4\u3067\u3059\u3002<\/p>\n\n\n\n<p><span class=\"swl-marker mark_orange\"><strong>\u3055\u3089\u306b\u30011\u7a2e\u985e\u306e\u85ac\u3060\u3051\u3067\u306f\u76ee\u6a19\u306e\u8840\u5727\u307e\u3067\u4e0b\u304c\u3089\u306a\u3044\u3053\u3068\u3082\u591a\u304f\u30012\u7a2e\u985e\u4ee5\u4e0a\u306e\u85ac\u3092\u7d44\u307f\u5408\u308f\u305b\u3066\u4f7f\u3046\u3053\u3068\u3082\u4e00\u822c\u7684\u3067\u3059\u3002<\/strong><\/span><\/p>\n\n\n\n<p>\u65e5\u672c\u306e\u9ad8\u8840\u5727\u6cbb\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u3067\u3082\u3001\u52b9\u679c\u7684\u3067\u5b89\u5168\u306a\u85ac\u306e\u7d44\u307f\u5408\u308f\u305b\u306b\u3064\u3044\u3066\u63a8\u5968\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3067\u306f\u3001\u5e74\u9f62\u3084\u6301\u75c5\u306b\u3088\u308b\u964d\u5727\u85ac\u306e\u9078\u3073\u65b9\u306e\u9055\u3044\u306b\u3064\u3044\u3066\u3001\u5177\u4f53\u7684\u306b\u898b\u3066\u3044\u304d\u307e\u3057\u3087\u3046\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u82e5\u3044\u4eba\u3068\u9ad8\u9f62\u8005\u3067\u306f\u63a8\u5968\u3055\u308c\u308b\u964d\u5727\u85ac\u304c\u9055\u3046<\/h3>\n\n\n\n<p>\u82e5\u3044\u65b9(\u3060\u3044\u305f\u304455\u6b73\u672a\u6e80)\u3068\u9ad8\u9f62\u8005\u3067\u306f\u3001\u9ad8\u8840\u5727\u306b\u306a\u308b\u4ed5\u7d44\u307f\u304c\u9055\u3046\u3053\u3068\u304c\u591a\u3044\u305f\u3081\u3001\u63a8\u5968\u3055\u308c\u308b\u964d\u5727\u85ac\u3082\u5909\u308f\u3063\u3066\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"has-text-align-center u-mb-ctrl u-mb-0\">\u5e74\u9f62\u5225\u306e\u63a8\u5968\u964d\u5727\u85ac<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><thead><tr><th>\u5e74\u9f62\u5c64<\/th><th>\u63a8\u5968\u3055\u308c\u308b\u85ac<\/th><th>\u7406\u7531<\/th><\/tr><\/thead><tbody><tr><td>\u82e5\u3044\u4eba(55\u6b73\u672a\u6e80)<\/td><td>ARB\u3001ACE\u963b\u5bb3\u85ac\u3001\u03b2\u906e\u65ad\u85ac\uff08\u8108\u304c\u901f\u3044\u5834\u5408\u306a\u3069\uff09<\/td><td>\u30ec\u30cb\u30f3\u30fb\u30a2\u30f3\u30b8\u30aa\u30c6\u30f3\u30b7\u30f3\u7cfb\u304c\u904e\u5270\u306b\u50cd\u3044\u3066\u3044\u308b\u3053\u3068\u304c\u539f\u56e0\u306e\u3053\u3068\u304c\u591a\u3044<\/td><\/tr><tr><td>\u9ad8\u9f62\u8005<\/td><td>\u30ab\u30eb\u30b7\u30a6\u30e0\u62ee\u6297\u85ac\u3001\u5229\u5c3f\u85ac<\/td><td>\u8840\u7ba1\u306e\u786c\u5316\u3084\u5869\u5206\u611f\u53d7\u6027\u306e\u4e0a\u6607\u304c\u4e3b\u306a\u539f\u56e0<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p><span class=\"swl-marker mark_orange\"><strong>\u82e5\u3044\u65b9\u306e\u9ad8\u8840\u5727\u306f\u3001\u300c\u30ec\u30cb\u30f3\u30fb\u30a2\u30f3\u30b8\u30aa\u30c6\u30f3\u30b7\u30f3\u7cfb\u300d\u3068\u3044\u3046\u4f53\u306e\u4e2d\u306e\u8840\u5727\u3092\u8abf\u6574\u3059\u308b\u30b7\u30b9\u30c6\u30e0\u304c\u50cd\u304d\u3059\u304e\u3066\u3044\u308b\u3053\u3068\u304c\u539f\u56e0\u306e\u3053\u3068\u304c\u591a\u3044<\/strong><\/span>\u305f\u3081\u3001\u3053\u306e\u30b7\u30b9\u30c6\u30e0\u3092\u6291\u3048\u308bARB\u3084ACE\u963b\u5bb3\u85ac\u304c\u52b9\u679c\u7684\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u307e\u305f\u3001\u82e5\u3044\u65b9\u3067\u306f\u4ea4\u611f\u795e\u7d4c\u306e\u6d3b\u52d5\u304c\u6d3b\u767a\u306a\u5834\u5408\u3082\u591a\u304f\u3001\u8108\u304c\u901f\u3044\u5834\u5408\u306a\u3069\u306b\u306f\u03b2\u906e\u65ad\u85ac\u304c\u9078\u3070\u308c\u308b\u3053\u3068\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u4e00\u65b9\u3001<span class=\"swl-marker mark_orange\"><strong>\u9ad8\u9f62\u8005\u306e\u9ad8\u8840\u5727\u306f\u3001\u5e74\u3092\u3068\u308b\u3053\u3068\u3067\u8840\u7ba1\u304c\u786c\u304f\u306a\u3063\u305f\u308a\u3001\u5869\u5206\u306b\u5bfe\u3057\u3066\u654f\u611f\u306b\u306a\u3063\u305f\u308a\u3059\u308b\u3053\u3068\u304c\u4e3b\u306a\u539f\u56e0<\/strong><\/span>\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u3053\u306e\u305f\u3081\u3001\u8840\u7ba1\u3092\u5e83\u3052\u308b\u30ab\u30eb\u30b7\u30a6\u30e0\u62ee\u6297\u85ac\u3084\u3001\u4f53\u306e\u4e2d\u306e\u5869\u5206\u3068\u6c34\u5206\u3092\u5916\u306b\u51fa\u3059\u5229\u5c3f\u85ac\u304c\u52b9\u679c\u7684\u3067\u3059\u3002<\/p>\n\n\n\n<div class=\"swell-block-capbox cap_box is-style-onborder_ttl\"><div class=\"cap_box_ttl\"><span>\u9ad8\u9f62\u8005\u3067\u306e\u7279\u5225\u306a\u6ce8\u610f\u70b9<\/span><\/div><div class=\"cap_box_content\">\n<ul class=\"wp-block-list\">\n<li>\u901a\u5e38\u306e\u534a\u5206\u306e\u91cf\u304b\u3089\u59cb\u3081\u308b<\/li>\n\n\n\n<li>1\u301c3\u30f6\u6708\u306e\u9593\u9694\u3067\u3086\u3063\u304f\u308a\u3068\u91cf\u3092\u5897\u3084\u3059<\/li>\n\n\n\n<li>\u7acb\u3061\u304f\u3089\u307f\u3084\u3075\u3089\u3064\u304d\u306b\u3088\u308b\u8ee2\u5012\u306b\u6ce8\u610f<\/li>\n\n\n\n<li>\u8840\u5727\u3092\u4e0b\u3052\u3059\u304e\u306a\u3044\u3088\u3046\u306b\u3059\u308b<\/li>\n<\/ul>\n<\/div><\/div>\n\n\n\n<p>\u305f\u3060\u3057\u3001\u9ad8\u9f62\u8005\u3067\u306f\u85ac\u306b\u3088\u308b\u526f\u4f5c\u7528\u304c\u51fa\u3084\u3059\u3044\u305f\u3081\u3001<a href=\"https:\/\/www.nature.com\/articles\/hr20148\">\u901a\u5e38\u306e\u534a\u5206\u306e\u91cf\u304b\u3089\u59cb\u3081\u3066\u30011\u301c3\u30f6\u6708\u306e\u9593\u9694\u3067\u3086\u3063\u304f\u308a\u3068\u91cf\u3092\u5897\u3084\u3057\u3066\u3044\u304d\u307e\u3059<\/a>\u3002<\/p>\n\n\n\n<p>\u7279\u306b\u7acb\u3061\u304f\u3089\u307f\u3084\u3075\u3089\u3064\u304d\u3067\u8ee2\u3093\u3067\u3057\u307e\u3046\u30ea\u30b9\u30af\u306b\u6ce8\u610f\u304c\u5fc5\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u7cd6\u5c3f\u75c5\u3084\u814e\u81d3\u75c5\u304c\u3042\u308b\u4eba\u306b\u9069\u3057\u305f\u964d\u5727\u85ac<\/h3>\n\n\n\n<p>\u7cd6\u5c3f\u75c5\u3084\u814e\u81d3\u75c5\u306a\u3069\u4ed6\u306e\u75c5\u6c17\u3082\u6301\u3063\u3066\u3044\u308b\u5834\u5408\u3001\u8840\u5727\u3092\u4e0b\u3052\u308b\u3060\u3051\u3067\u306a\u304f\u3001\u3053\u308c\u3089\u306e\u75c5\u6c17\u304c\u9032\u3080\u306e\u3092\u6291\u3048\u308b\u52b9\u679c\u3082\u671f\u5f85\u3067\u304d\u308b\u964d\u5727\u85ac\u304c\u9078\u3070\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"has-text-align-center u-mb-ctrl u-mb-0\">\u5408\u4f75\u75c7\u5225\u306e\u63a8\u5968\u964d\u5727\u85ac<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><thead><tr><th>\u5408\u4f75\u75c7<\/th><th>\u63a8\u5968\u3055\u308c\u308b\u85ac<\/th><th>\u671f\u5f85\u3067\u304d\u308b\u52b9\u679c<\/th><\/tr><\/thead><tbody><tr><td>\u7cd6\u5c3f\u75c5<\/td><td>ARB\u3001ACE\u963b\u5bb3\u85ac<\/td><td>\u814e\u81d3\u306e\u4fdd\u8b77\u3001\u30bf\u30f3\u30d1\u30af\u5c3f\u306e\u6e1b\u5c11<\/td><\/tr><tr><td>\u6162\u6027\u814e\u81d3\u75c5<\/td><td>ARB\u3001ACE\u963b\u5bb3\u85ac<\/td><td>\u814e\u6a5f\u80fd\u60aa\u5316\u306e\u9045\u5ef6<\/td><\/tr><tr><td>\u5fc3\u4e0d\u5168<\/td><td>ARB\u3001ACE\u963b\u5bb3\u85ac\u3001\u03b2\u906e\u65ad\u85ac\u3001MR\u62ee\u6297\u85ac<\/td><td>\u5fc3\u81d3\u3078\u306e\u8ca0\u62c5\u8efd\u6e1b\u3001\u4e88\u5f8c\u6539\u5584<\/td><\/tr><tr><td>\u5fc3\u7b4b\u6897\u585e\u5f8c<\/td><td>\u03b2\u906e\u65ad\u85ac\u3001ARB\u3001ACE\u963b\u5bb3\u85ac<\/td><td>\u518d\u767a\u4e88\u9632\u3001\u4e88\u5f8c\u6539\u5584<\/td><\/tr><tr><td>\u524d\u7acb\u817a\u80a5\u5927\u75c7(\u7537\u6027)<\/td><td>\u03b1\u906e\u65ad\u85ac<\/td><td>\u6392\u5c3f\u969c\u5bb3\u306e\u6539\u5584\u3082\u671f\u5f85<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p><span class=\"swl-marker mark_orange\"><strong>\u7cd6\u5c3f\u75c5\u304c\u3042\u308b\u65b9\u306b\u306f\u3001ARB\u3084ACE\u963b\u5bb3\u85ac\u304c\u7b2c\u4e00\u9078\u629e<\/strong><\/span>\u3068\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3053\u308c\u3089\u306e\u85ac\u306f\u8840\u5727\u3092\u4e0b\u3052\u308b\u3060\u3051\u3067\u306a\u304f\u3001\u814e\u81d3\u306e\u7cf8\u7403\u4f53(\u8840\u6db2\u3092\u308d\u904e\u3059\u308b\u30d5\u30a3\u30eb\u30bf\u30fc\u306e\u3088\u3046\u306a\u90e8\u5206)\u3092\u4fdd\u8b77\u3057\u3001<a href=\"https:\/\/diabetesjournals.org\/care\/article\/48\/Supplement_1\/S239\/157554\/11-Chronic-Kidney-Disease-and-Risk-Management\">\u5c3f\u306b\u30bf\u30f3\u30d1\u30af\u304c\u51fa\u308b\u306e\u3092\u6e1b\u3089\u3059\u50cd\u304d<\/a>\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u7cd6\u5c3f\u75c5\u3067\u814e\u81d3\u304c\u60aa\u304f\u306a\u308b\u306e\u3092\u9045\u3089\u305b\u3001\u5c06\u6765\u7684\u306b\u900f\u6790\u304c\u5fc5\u8981\u306b\u306a\u308b\u30ea\u30b9\u30af\u3092\u4e0b\u3052\u308b\u52b9\u679c\u304c\u305f\u304f\u3055\u3093\u306e\u7814\u7a76\u3067\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p><span class=\"swl-marker mark_orange\"><strong>\u6162\u6027\u814e\u81d3\u75c5\u306e\u65b9\u306b\u3082\u3001ARB\u3084ACE\u963b\u5bb3\u85ac\u304c\u63a8\u5968\u3055\u308c\u307e\u3059\u3002<\/strong><\/span><\/p>\n\n\n\n<p>\u305f\u3060\u3057\u3001\u3053\u308c\u3089\u306e\u85ac\u3092\u4f7f\u3044\u59cb\u3081\u308b\u3068\u3001\u4e00\u6642\u7684\u306b\u814e\u81d3\u306e\u50cd\u304d\u3092\u793a\u3059\u6570\u5024(\u8840\u6e05\u30af\u30ec\u30a2\u30c1\u30cb\u30f3\u5024)\u304c\u5c11\u3057\u4e0a\u304c\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u304c\u3001\u901a\u5e38\u306f\u554f\u984c\u306a\u3044\u3053\u3068\u304c\u591a\u3044\u3082\u306e\u306e\u3001\u4e0a\u6607\u306e\u7a0b\u5ea6\u3092\u533b\u5e2b\u304c\u78ba\u8a8d\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u304a\u533b\u8005\u3055\u3093\u306f\u8840\u6db2\u691c\u67fb\u3067\u814e\u81d3\u306e\u50cd\u304d\u3068\u30ab\u30ea\u30a6\u30e0\u306e\u5024\u3092\u5b9a\u671f\u7684\u306b\u30c1\u30a7\u30c3\u30af\u3057\u306a\u304c\u3089\u6cbb\u7642\u3092\u9032\u3081\u307e\u3059\u3002<\/p>\n\n\n\n<p><span class=\"swl-marker mark_orange\"><strong>\u5fc3\u4e0d\u5168\u304c\u3042\u308b\u65b9\u306b\u306f\u3001ARB\u3001ACE\u963b\u5bb3\u85ac\u3001\u03b2\u906e\u65ad\u85ac\u3001MR\u62ee\u6297\u85ac\u304c\u63a8\u5968\u3055\u308c\u307e\u3059\u3002<\/strong><\/span><\/p>\n\n\n\n<p>\u3053\u308c\u3089\u306e\u85ac\u306f\u5fc3\u81d3\u3078\u306e\u8ca0\u62c5\u3092\u8efd\u304f\u3057\u3001\u5fc3\u4e0d\u5168\u304c\u60aa\u304f\u306a\u308b\u306e\u3092\u9632\u3050\u52b9\u679c\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"is-style-balloon_box\">\u598a\u5a20\u4e2d\u30fb\u598a\u5a20\u306e\u53ef\u80fd\u6027\u304c\u3042\u308b\u5973\u6027\u3078\u306e\u91cd\u8981\u306a\u6ce8\u610f<\/p>\n\n\n\n<p>\u598a\u5a20\u4e2d\u306e\u65b9\u3084\u598a\u5a20\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u5973\u6027\u3067\u306f\u3001\u4ee5\u4e0b\u306e\u85ac\u306f\u4f7f\u3063\u3066\u306f\u3044\u3051\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<div class=\"swell-block-capbox cap_box is-style-onborder_ttl\"><div class=\"cap_box_ttl\"><span>\u598a\u5a20\u4e2d\u30fb\u598a\u5a20\u306e\u53ef\u80fd\u6027\u304c\u3042\u308b\u5973\u6027\u304c\u4f7f\u7528\u3067\u304d\u306a\u3044\u85ac<\/span><\/div><div class=\"cap_box_content\">\n<ul class=\"wp-block-list\">\n<li>ARB<\/li>\n\n\n\n<li>ACE\u963b\u5bb3\u85ac<\/li>\n\n\n\n<li>\u30ec\u30cb\u30f3\u963b\u5bb3\u85ac<\/li>\n<\/ul>\n<\/div><\/div>\n\n\n\n<p>\u3053\u308c\u3089\u306f\u304a\u8179\u306e\u8d64\u3061\u3083\u3093\u306b\u91cd\u5927\u306a\u5f71\u97ff\u3092\u53ca\u307c\u3059\u53ef\u80fd\u6027\u304c\u3042\u308b\u305f\u3081\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u598a\u5a20\u9ad8\u8840\u5727\u75c7\u5019\u7fa4\u306e\u6cbb\u7642\u306b\u306f\u3001\u30e1\u30c1\u30eb\u30c9\u30d1\u3084\u30e9\u30d9\u30bf\u30ed\u30fc\u30eb\u306a\u3069\u3001\u598a\u5a20\u4e2d\u3067\u3082\u6bd4\u8f03\u7684\u5b89\u5168\u306b\u4f7f\u3048\u308b\u85ac\u304c\u9078\u3070\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u8907\u6570\u306e\u85ac\u3092\u7d44\u307f\u5408\u308f\u305b\u3066\u8840\u5727\u3092\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u3059\u308b\u3053\u3068\u3082\u591a\u3044<\/h3>\n\n\n\n<p>1\u7a2e\u985e\u306e\u964d\u5727\u85ac\u3060\u3051\u3067\u306f\u76ee\u6a19\u306e\u8840\u5727\u307e\u3067\u4e0b\u304c\u3089\u306a\u3044\u5834\u5408\u30012\u7a2e\u985e\u4ee5\u4e0a\u306e\u85ac\u3092\u7d44\u307f\u5408\u308f\u305b\u3066\u4f7f\u3046\u3053\u3068\u304c\u4e00\u822c\u7684\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u5b9f\u969b\u3001\u9ad8\u8840\u5727\u306e\u65b9\u306e\u591a\u304f\u306f\u3001\u6700\u7d42\u7684\u306b<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC6900198\/\">2\u301c3\u7a2e\u985e\u306e\u964d\u5727\u85ac\u3092\u4e00\u7dd2\u306b\u98f2\u3080\u3053\u3068\u306b\u306a\u308a\u307e\u3059<\/a>\u3002<\/p>\n\n\n\n<div class=\"swell-block-capbox cap_box is-style-onborder_ttl\"><div class=\"cap_box_ttl\"><span>\u4f75\u7528\u7642\u6cd5\u306e\u30e1\u30ea\u30c3\u30c8<\/span><\/div><div class=\"cap_box_content\">\n<ul class=\"wp-block-list\">\n<li>\u7570\u306a\u308b\u4ed5\u7d44\u307f\u3067\u8840\u5727\u3092\u4e0b\u3052\u308b\u305f\u3081\u3001\u5358\u72ec\u4f7f\u7528\u3088\u308a\u5927\u304d\u306a\u52b9\u679c<\/li>\n\n\n\n<li>\u305d\u308c\u305e\u308c\u306e\u85ac\u306e\u91cf\u3092\u6e1b\u3089\u305b\u308b\u305f\u3081\u3001\u526f\u4f5c\u7528\u306e\u30ea\u30b9\u30af\u304c\u6e1b\u308b<\/li>\n\n\n\n<li>1\u9320\u306b\u8907\u6570\u306e\u6210\u5206\u304c\u5165\u3063\u305f\u914d\u5408\u5264\u3067\u670d\u85ac\u304c\u7c21\u5358\u306b\u306a\u308b<\/li>\n<\/ul>\n<\/div><\/div>\n\n\n\n<p>\u8907\u6570\u306e\u85ac\u3092\u7d44\u307f\u5408\u308f\u305b\u308b\u3053\u3068\u306b\u306f\u3001\u3044\u304f\u3064\u304b\u306e\u826f\u3044\u70b9\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u307e\u305a\u3001\u9055\u3046\u4ed5\u7d44\u307f\u3067\u8840\u5727\u3092\u4e0b\u3052\u308b\u85ac\u3092\u4e00\u7dd2\u306b\u4f7f\u3046\u3053\u3068\u3067\u30011\u7a2e\u985e\u3060\u3051\u3067\u4f7f\u3046\u3088\u308a\u3082\u5927\u304d\u304f\u8840\u5727\u3092\u4e0b\u3052\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u7814\u7a76\u306b\u3088\u308b\u3068\u3001<span class=\"swl-marker mark_orange\"><strong>2\u7a2e\u985e\u306e\u9055\u3046\u30bf\u30a4\u30d7\u306e\u964d\u5727\u85ac\u3092\u7d44\u307f\u5408\u308f\u305b\u305f\u3068\u304d\u306e\u8840\u5727\u3092\u4e0b\u3052\u308b\u52b9\u679c\u306f\u30011\u7a2e\u985e\u306e\u85ac\u306e\u91cf\u30922\u500d\u306b\u3057\u305f\u3068\u304d\u306e\u7d045\u500d<\/strong><\/span>\u306b\u3082\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p>2\u3064\u306e\u7570\u306a\u308b\u30af\u30e9\u30b9\u306e\u85ac\u5264\u3092\u4f75\u7528\u3059\u308b\u3053\u3068\u306b\u3088\u308b\u8ffd\u52a0\u306e\u8840\u5727\u4f4e\u4e0b\u306f\u30011\u3064\u306e\u85ac\u5264\u306e\u7528\u91cf\u30922\u500d\u306b\u3057\u305f\u5834\u5408\u306e\u7d045\u500d\u3067\u3059\u3002<\/p>\n<cite>\u5f15\u7528\uff1aPubMed <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/19272490\/\">Combination therapy versus monotherapy in reducing blood pressure: meta-analysis on 11,000 participants from 42 trials<\/a><\/cite><\/blockquote>\n\n\n\n<p>\u307e\u305f\u3001\u4e00\u7dd2\u306b\u4f7f\u3046\u3053\u3068\u3067\u3001\u305d\u308c\u305e\u308c\u306e\u85ac\u306e\u91cf\u3092\u5c11\u306a\u304f\u3067\u304d\u308b\u305f\u3081\u3001\u526f\u4f5c\u7528\u304c\u51fa\u308b\u30ea\u30b9\u30af\u3092\u6e1b\u3089\u3059\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u305f\u3068\u3048\u3070\u3001\u30ab\u30eb\u30b7\u30a6\u30e0\u62ee\u6297\u85ac\u3067\u8db3\u304c\u3080\u304f\u3080\u306e\u304c\u554f\u984c\u306b\u306a\u308b\u5834\u5408\u3001ARB\u3092\u4e00\u7dd2\u306b\u4f7f\u3046\u3053\u3068\u3067\u3001\u30ab\u30eb\u30b7\u30a6\u30e0\u62ee\u6297\u85ac\u306e\u91cf\u3092\u6e1b\u3089\u3057\u306a\u304c\u3089\u3082\u5341\u5206\u306b\u8840\u5727\u3092\u4e0b\u3052\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"has-text-align-center u-mb-ctrl u-mb-0\">\u63a8\u5968\u3055\u308c\u308b\u85ac\u306e\u7d44\u307f\u5408\u308f\u305b<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><thead><tr><th>\u7d44\u307f\u5408\u308f\u305b<\/th><th>\u7279\u5fb4<\/th><\/tr><\/thead><tbody><tr><td>\u30ab\u30eb\u30b7\u30a6\u30e0\u62ee\u6297\u85ac + ARB(\u307e\u305f\u306fACE\u963b\u5bb3\u85ac)<\/td><td>\u6700\u3082\u4e00\u822c\u7684\u3002\u4e92\u3044\u306e\u526f\u4f5c\u7528\u3092\u8efd\u6e1b\u3057\u3042\u3046<\/td><\/tr><tr><td>\u30ab\u30eb\u30b7\u30a6\u30e0\u62ee\u6297\u85ac + \u5229\u5c3f\u85ac<\/td><td>\u8840\u5727\u3092\u4e0b\u3052\u308b\u52b9\u679c\u304c\u9ad8\u3044<\/td><\/tr><tr><td>ARB(\u307e\u305f\u306fACE\u963b\u5bb3\u85ac) + \u5229\u5c3f\u85ac<\/td><td>\u814e\u81d3\u3084\u5fc3\u81d3\u3092\u5b88\u308b\u52b9\u679c\u3082\u671f\u5f85\u3067\u304d\u308b<\/td><\/tr><tr><td>\u30ab\u30eb\u30b7\u30a6\u30e0\u62ee\u6297\u85ac + \u03b2\u906e\u65ad\u85ac<\/td><td>\u5fc3\u81d3\u75c5\u304c\u3042\u308b\u65b9\u306b\u9069\u3057\u3066\u3044\u308b<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p>\u65e5\u672c\u306e\u9ad8\u8840\u5727\u6cbb\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u3067\u306f\u3001\u4ee5\u4e0b\u306e\u7d44\u307f\u5408\u308f\u305b\u304c\u63a8\u5968\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"swell-block-capbox cap_box is-style-onborder_ttl\"><div class=\"cap_box_ttl\"><span>\u63a8\u5968\u3055\u308c\u308b\u7d44\u307f\u5408\u308f\u305b<\/span><\/div><div class=\"cap_box_content\">\n<ul class=\"wp-block-list\">\n<li><span class=\"swl-marker mark_orange\"><strong>\u30ab\u30eb\u30b7\u30a6\u30e0\u62ee\u6297\u85ac\u3068ARB(\u307e\u305f\u306fACE\u963b\u5bb3\u85ac)<\/strong><\/span><\/li>\n\n\n\n<li><span class=\"swl-marker mark_orange\"><strong>\u30ab\u30eb\u30b7\u30a6\u30e0\u62ee\u6297\u85ac\u3068\u5229\u5c3f\u85ac<\/strong><\/span><\/li>\n\n\n\n<li><span class=\"swl-marker mark_orange\"><strong>ARB(\u307e\u305f\u306fACE\u963b\u5bb3\u85ac)\u3068\u5229\u5c3f\u85ac<\/strong><\/span><\/li>\n<\/ul>\n<\/div><\/div>\n\n\n\n<p>\u3053\u308c\u3089\u306e\u7d44\u307f\u5408\u308f\u305b\u306f\u76f8\u6027\u304c\u3088\u304f\u3001\u8840\u5727\u3092\u4e0b\u3052\u308b\u52b9\u679c\u304c\u9ad8\u3044\u3053\u3068\u304c\u7814\u7a76\u3067\u78ba\u304b\u3081\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u5b9f\u969b\u3001\u3053\u308c\u3089\u306e\u7d44\u307f\u5408\u308f\u305b\u30921\u3064\u306e\u9320\u5264\u306b\u3057\u305f\u914d\u5408\u5264\u3082\u305f\u304f\u3055\u3093\u58f2\u3089\u308c\u3066\u3044\u3066\u3001\u98f2\u3080\u624b\u9593\u304c\u6e1b\u308b\u3068\u3068\u3082\u306b\u3001\u98f2\u307f\u5fd8\u308c\u3092\u9632\u3050\u52b9\u679c\u3082\u671f\u5f85\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u4e00\u65b9\u3001\u63a8\u5968\u3055\u308c\u306a\u3044\u7d44\u307f\u5408\u308f\u305b\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"swell-block-capbox cap_box is-style-onborder_ttl\"><div class=\"cap_box_ttl\"><span>\u907f\u3051\u308b\u3079\u304d\u7d44\u307f\u5408\u308f\u305b<\/span><\/div><div class=\"cap_box_content\">\n<ul class=\"wp-block-list\">\n<li>ARB + ACE\u963b\u5bb3\u85ac(\u814e\u6a5f\u80fd\u969c\u5bb3\u3084\u9ad8\u30ab\u30ea\u30a6\u30e0\u8840\u75c7\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u307e\u308b)<\/li>\n<\/ul>\n<\/div><\/div>\n\n\n\n<p>ARB\u3068ACE\u963b\u5bb3\u85ac\u3092\u4e00\u7dd2\u306b\u4f7f\u3046\u3068\u3001\u814e\u81d3\u306e\u50cd\u304d\u304c\u60aa\u304f\u306a\u3063\u305f\u308a\u9ad8\u30ab\u30ea\u30a6\u30e0\u8840\u75c7\u306b\u306a\u3063\u305f\u308a\u3059\u308b\u30ea\u30b9\u30af\u304c\u9ad8\u307e\u308b\u305f\u3081\u3001<a href=\"https:\/\/kdigo.org\/wp-content\/uploads\/2016\/10\/KDIGO_BP_Exec_Summary_final.pdf\">\u901a\u5e38\u306f\u907f\u3051\u308b\u3079\u304d<\/a>\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u964d\u5727\u85ac\u306f\u6bce\u65e5\u540c\u3058\u6642\u9593\u306b\u98f2\u307f\u7d9a\u3051\u308b\u3053\u3068\u304c\u5927\u5207<\/h2>\n\n\n\n<p>\u964d\u5727\u85ac\u306e\u52b9\u679c\u3092\u6700\u5927\u9650\u306b\u5f15\u304d\u51fa\u3057\u3001\u8133\u5352\u4e2d\u3084\u5fc3\u7b4b\u6897\u585e\u306a\u3069\u306e\u6016\u3044\u75c5\u6c17\u3092\u9632\u3050\u305f\u3081\u306b\u306f\u3001\u6b63\u3057\u3044\u98f2\u307f\u65b9\u3092\u5b88\u308b\u3053\u3068\u304c\u3068\u3066\u3082\u5927\u5207\u3067\u3059\u3002<\/p>\n\n\n\n<p><span class=\"swl-marker mark_orange\"><strong>\u964d\u5727\u85ac\u306f\u300c\u98f2\u3093\u3060\u3068\u304d\u3060\u3051\u8840\u5727\u3092\u4e0b\u3052\u308b\u300d\u3082\u306e\u3067\u306f\u306a\u304f\u3001\u6bce\u65e5\u7d9a\u3051\u3066\u98f2\u3080\u3053\u3068\u3067\u3001\u3044\u3064\u3082\u8840\u5727\u3092\u5b89\u5b9a\u3057\u305f\u72b6\u614b\u306b\u4fdd\u3064\u305f\u3081\u306e\u85ac\u3067\u3059\u3002<\/strong><\/span><\/p>\n\n\n\n<p>\u304d\u3061\u3093\u3068\u98f2\u307e\u306a\u304b\u3063\u305f\u308a\u98f2\u307f\u5fd8\u308c\u304c\u7d9a\u3044\u305f\u308a\u3059\u308b\u3068\u3001\u8840\u5727\u304c\u5b89\u5b9a\u305b\u305a\u4e0a\u304c\u3063\u305f\u308a\u4e0b\u304c\u3063\u305f\u308a\u3092\u7e70\u308a\u8fd4\u3059\u3053\u3068\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3053\u306e\u8840\u5727\u306e\u5909\u52d5\u81ea\u4f53\u304c\u8840\u7ba1\u306b\u30c0\u30e1\u30fc\u30b8\u3092\u4e0e\u3048\u3066\u3001\u8133\u5352\u4e2d\u3084\u5fc3\u7b4b\u6897\u585e\u306e\u30ea\u30b9\u30af\u3092\u9ad8\u3081\u3066\u3057\u307e\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u5b89\u5b9a\u3057\u305f\u8840\u5727\u3092\u30ad\u30fc\u30d7\u3059\u308b\u3053\u3068\u304c\u3001\u964d\u5727\u85ac\u6cbb\u7642\u306e\u4e00\u756a\u5927\u4e8b\u306a\u76ee\u7684\u306a\u306e\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u307e\u305f\u3001\u964d\u5727\u85ac\u306e\u4e2d\u306b\u306f\u3001\u6025\u306b\u98f2\u3080\u306e\u3092\u3084\u3081\u308b\u3068\u5371\u967a\u306a\u72b6\u614b\u306b\u306a\u308b\u3082\u306e\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p><span class=\"swl-marker mark_orange\"><strong>\u7279\u306b\u03b2\u906e\u65ad\u85ac\u3084\u4e2d\u67a2\u6027\u4ea4\u611f\u795e\u7d4c\u6291\u5236\u85ac\u306f\u3001\u6025\u306b\u3084\u3081\u308b\u3068\u8840\u5727\u304c\u6025\u6fc0\u306b\u4e0a\u304c\u3063\u305f\u308a\u3001\u72ed\u5fc3\u75c7\u306e\u767a\u4f5c\u304c\u8d77\u3053\u3063\u305f\u308a\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/strong><\/span><\/p>\n\n\n\n<p>\u3055\u3089\u306b\u3001\u4e00\u90e8\u306e\u964d\u5727\u85ac\u306f\u7279\u5b9a\u306e\u98df\u3079\u7269\u3084\u98f2\u307f\u7269\u3068\u4e00\u7dd2\u306b\u6442\u308b\u3068\u826f\u304f\u306a\u3044\u53cd\u5fdc\u304c\u8d77\u304d\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3053\u308c\u3089\u306e\u6ce8\u610f\u70b9\u3092\u7406\u89e3\u3057\u3066\u3001\u6b63\u3057\u304f\u98f2\u3080\u3053\u3068\u304c\u3001\u5b89\u5168\u3067\u52b9\u679c\u7684\u306a\u9ad8\u8840\u5727\u6cbb\u7642\u306b\u3064\u306a\u304c\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3067\u306f\u3001\u964d\u5727\u85ac\u3092\u98f2\u3080\u3068\u304d\u306e\u5927\u5207\u306a\u30dd\u30a4\u30f3\u30c8\u306b\u3064\u3044\u3066\u8a73\u3057\u304f\u898b\u3066\u3044\u304d\u307e\u3057\u3087\u3046\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u964d\u5727\u85ac\u306e\u52b9\u679c\u3092\u6700\u5927\u9650\u306b\u5f15\u304d\u51fa\u3059\u306b\u306f\u898f\u5247\u6b63\u3057\u3044\u670d\u7528\u304c\u5fc5\u8981<\/h3>\n\n\n\n<p>\u964d\u5727\u85ac\u306e\u591a\u304f\u306f\u3001<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK9626\/\">1\u65e51\u56de\u98f2\u3081\u307024\u6642\u9593\u8840\u5727\u3092\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u3067\u304d\u308b<\/a>\u3088\u3046\u306b\u4f5c\u3089\u308c\u3066\u3044\u307e\u3059\uff08\u85ac\u306e\u7a2e\u985e\u306b\u3088\u3063\u3066\u306f1\u65e52\u56de\u4ee5\u4e0a\u306e\u670d\u7528\u304c\u5fc5\u8981\u306a\u5834\u5408\u3082\u3042\u308a\u307e\u3059\uff09\u3002<\/p>\n\n\n\n<p>\u3057\u304b\u3057\u3001\u305d\u308c\u306f\u6bce\u65e5\u3060\u3044\u305f\u3044\u540c\u3058\u6642\u9593\u306b\u98f2\u3093\u3060\u5834\u5408\u306e\u8a71\u3067\u3059\u3002<\/p>\n\n\n\n<p><span class=\"swl-marker mark_orange\"><strong>\u98f2\u3080\u6642\u9593\u304c\u30d0\u30e9\u30d0\u30e9\u3060\u3063\u305f\u308a\u3001\u98f2\u307f\u5fd8\u308c\u304c\u4f55\u5ea6\u3082\u3042\u3063\u305f\u308a\u3059\u308b\u3068\u3001\u8840\u6db2\u306e\u4e2d\u306e\u85ac\u306e\u6fc3\u5ea6\u304c\u5b89\u5b9a\u305b\u305a\u3001\u8840\u5727\u304c\u5909\u52d5\u3057\u3066\u3057\u307e\u3044\u307e\u3059\u3002<\/strong><\/span><\/p>\n\n\n\n<div class=\"swell-block-capbox cap_box is-style-onborder_ttl\"><div class=\"cap_box_ttl\"><span>\u670d\u7528\u6642\u9593\u306e\u6c7a\u3081\u65b9<\/span><\/div><div class=\"cap_box_content\">\n<ul class=\"wp-block-list\">\n<li>\u671d\u98df\u5f8c\u306b\u98f2\u3080 \u2192 \u65e9\u671d\u306e\u8840\u5727\u304c\u9ad8\u304f\u306a\u308a\u3084\u3059\u3044\u65b9<\/li>\n\n\n\n<li>\u5c31\u5bdd\u524d\u306b\u98f2\u3080 \u2192 \u591c\u9593\u304b\u3089\u671d\u306b\u304b\u3051\u3066\u8840\u5727\u304c\u4e0a\u304c\u308a\u3084\u3059\u3044\u65b9<\/li>\n<\/ul>\n<\/div><\/div>\n\n\n\n<p>\u671d\u3054\u306f\u3093\u306e\u5f8c\u306b\u98f2\u3080\u306e\u304b\u3001\u5bdd\u308b\u524d\u306b\u98f2\u3080\u306e\u304b\u306f\u3001\u85ac\u306e\u7a2e\u985e\u3084\u60a3\u8005\u3055\u3093\u306e\u8840\u5727\u306e\u30d1\u30bf\u30fc\u30f3\u306b\u3088\u3063\u3066\u304a\u533b\u8005\u3055\u3093\u304c\u6c7a\u3081\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u305f\u3068\u3048\u3070\u3001\u671d\u65e9\u304f\u306b\u8840\u5727\u304c\u9ad8\u304f\u306a\u308a\u3084\u3059\u3044\u65b9\u306f\u671d\u306b\u98f2\u307f\u3001\u591c\u304b\u3089\u671d\u306b\u304b\u3051\u3066\u8840\u5727\u304c\u4e0a\u304c\u308a\u3084\u3059\u3044\u65b9\u306f\u5bdd\u308b\u524d\u306b\u98f2\u3080\u3068\u3044\u3063\u305f\u5177\u5408\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"has-text-align-center u-mb-ctrl u-mb-0\">\u98f2\u307f\u5fd8\u308c\u305f\u3068\u304d\u306e\u5bfe\u51e6\u6cd5<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><thead><tr><th>\u72b6\u6cc1<\/th><th>\u5bfe\u51e6\u6cd5<\/th><\/tr><\/thead><tbody><tr><td>\u6b21\u306e\u670d\u7528\u6642\u9593\u307e\u3067\u5341\u5206\u306a\u6642\u9593\u304c\u3042\u308b<\/td><td>\u6c17\u3065\u3044\u305f\u6642\u70b9\u30671\u56de\u5206\u3092\u670d\u7528<\/td><\/tr><tr><td>\u6b21\u306e\u670d\u7528\u6642\u9593\u307e\u3067\u8fd1\u3044<\/td><td>\u98f2\u307f\u5fd8\u308c\u305f\u5206\u306f\u98db\u3070\u3057\u3066\u3001\u6b21\u56de\u304b\u3089\u901a\u5e38\u901a\u308a\u670d\u7528<\/td><\/tr><tr><td>\u7d76\u5bfe\u306b\u3084\u3063\u3066\u306f\u3044\u3051\u306a\u3044\u3053\u3068<\/td><td>2\u56de\u5206\u3092\u307e\u3068\u3081\u3066\u98f2\u3080(\u8840\u5727\u304c\u4e0b\u304c\u308a\u3059\u304e\u3066\u5371\u967a)<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p>\u3082\u3057\u98f2\u307f\u5fd8\u308c\u306b\u6c17\u3065\u3044\u305f\u3068\u304d\u306f\u3001\u6b21\u306b\u98f2\u3080\u6642\u9593\u304c\u8fd1\u3044\u5834\u5408\u3092\u9664\u3044\u3066\u3001\u6c17\u3065\u3044\u305f\u6642\u70b9\u3067\u98f2\u307f\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u305f\u3060\u3057\u3001\u6b21\u306b\u98f2\u3080\u6642\u9593\u304c\u8fd1\u3044\u5834\u5408\u306f1\u56de\u5206\u3092\u98db\u3070\u3057\u3001\u7d76\u5bfe\u306b<a href=\"https:\/\/www.sps.nhs.uk\/articles\/advising-on-missed-or-delayed-doses-of-medicines\/\">2\u56de\u5206\u3092\u307e\u3068\u3081\u3066\u98f2\u3093\u3067\u306f\u3044\u3051\u307e\u305b\u3093<\/a>\u3002<\/p>\n\n\n\n<p><span class=\"swl-marker mark_orange\"><strong>2\u56de\u5206\u3092\u307e\u3068\u3081\u3066\u98f2\u3080\u3068\u3001\u8840\u5727\u304c\u4e0b\u304c\u308a\u3059\u304e\u3066\u5371\u967a\u3067\u3059\u3002<\/strong><\/span><\/p>\n\n\n\n<p>\u5177\u4f53\u7684\u306a\u5224\u65ad\u57fa\u6e96\u306f\u85ac\u306b\u3088\u3063\u3066\u7570\u306a\u308b\u305f\u3081\u3001\u4e8b\u524d\u306b\u533b\u5e2b\u3084\u85ac\u5264\u5e2b\u306b\u78ba\u8a8d\u3057\u3066\u304a\u304d\u307e\u3057\u3087\u3046\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u81ea\u5df1\u5224\u65ad\u3067\u85ac\u3092\u3084\u3081\u308b\u3068\u8840\u5727\u304c\u6025\u4e0a\u6607\u3059\u308b\u5371\u967a\u6027\u304c\u3042\u308b<\/h3>\n\n\n\n<p>\u300c\u8840\u5727\u304c\u6b63\u5e38\u306b\u306a\u3063\u305f\u304b\u3089\u3001\u3082\u3046\u85ac\u306f\u5fc5\u8981\u306a\u3044\u300d\u3068\u8003\u3048\u3066\u3001\u81ea\u5206\u306e\u5224\u65ad\u3067\u98f2\u3080\u306e\u3092\u3084\u3081\u3066\u3057\u307e\u3046\u65b9\u304c\u3044\u307e\u3059\u304c\u3001\u3053\u308c\u306f\u3068\u3066\u3082\u5371\u967a\u3067\u3059\u3002<\/p>\n\n\n\n<p><span class=\"swl-marker mark_orange\"><strong>\u964d\u5727\u85ac\u3067\u8840\u5727\u304c\u4e0b\u304c\u3063\u3066\u3044\u308b\u306e\u306f\u3001\u85ac\u304c\u52b9\u3044\u3066\u3044\u308b\u304b\u3089\u3067\u3042\u3063\u3066\u3001\u9ad8\u8840\u5727\u304c\u6cbb\u3063\u305f\u308f\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/strong><\/span><\/p>\n\n\n\n<p>\u85ac\u3092\u3084\u3081\u308c\u3070\u3001\u307b\u3068\u3093\u3069\u306e\u5834\u5408\u3001\u8840\u5727\u306f\u307e\u305f\u4e0a\u304c\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"swell-block-capbox cap_box is-style-onborder_ttl\"><div class=\"cap_box_ttl\"><span>\u81ea\u5df1\u5224\u65ad\u3067\u4e2d\u6b62\u3059\u308b\u3068\u8d77\u3053\u308a\u3046\u308b\u5371\u967a<\/span><\/div><div class=\"cap_box_content\">\n<ul class=\"wp-block-list\">\n<li>\u8840\u5727\u306e\u6025\u6fc0\u306a\u4e0a\u6607(\u30ea\u30d0\u30a6\u30f3\u30c9\u73fe\u8c61)<\/li>\n\n\n\n<li>\u72ed\u5fc3\u75c7\u306e\u767a\u4f5c<\/li>\n\n\n\n<li>\u8133\u5352\u4e2d\u306e\u30ea\u30b9\u30af\u5897\u52a0<\/li>\n\n\n\n<li>\u5fc3\u7b4b\u6897\u585e\u306e\u30ea\u30b9\u30af\u5897\u52a0<\/li>\n<\/ul>\n<\/div><\/div>\n\n\n\n<p>\u7279\u306b\u03b2\u906e\u65ad\u85ac\u3084\u4e2d\u67a2\u6027\u4ea4\u611f\u795e\u7d4c\u6291\u5236\u85ac\u3092\u6025\u306b\u3084\u3081\u308b\u3068\u3001\u8840\u5727\u304c\u6025\u6fc0\u306b\u4e0a\u304c\u3063\u305f\u308a(\u30ea\u30d0\u30a6\u30f3\u30c9\u73fe\u8c61)\u3001\u72ed\u5fc3\u75c7\u306e\u767a\u4f5c\u304c\u8d77\u3053\u3063\u305f\u308a\u3059\u308b\u5371\u967a\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p><span class=\"swl-marker mark_orange\"><strong>\u964d\u5727\u85ac\u3092\u3084\u3081\u305f\u308a\u91cf\u3092\u6e1b\u3089\u3057\u305f\u308a\u3059\u308b\u306e\u306f\u3001\u5fc5\u305a\u304a\u533b\u8005\u3055\u3093\u306e\u6307\u793a\u306e\u3082\u3068\u3067\u884c\u3046\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/strong><\/span><\/p>\n\n\n\n<p>\u751f\u6d3b\u7fd2\u6163\u306e\u6539\u5584\u3067\u8840\u5727\u304c\u5b89\u5b9a\u3057\u3066\u3001\u9577\u3044\u9593\u3044\u3044\u72b6\u614b\u304c\u7d9a\u3044\u3066\u3044\u308b\u5834\u5408\u306b\u306f\u3001\u304a\u533b\u8005\u3055\u3093\u306e\u5224\u65ad\u3067\u85ac\u3092\u6e1b\u3089\u3057\u305f\u308a\u3001\u6700\u7d42\u7684\u306b\u3084\u3081\u305f\u308a\u3067\u304d\u308b\u53ef\u80fd\u6027\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3057\u304b\u3057\u3001\u305d\u306e\u5834\u5408\u3067\u3082\u3001\u98df\u4e8b\u7642\u6cd5\u3084\u904b\u52d5\u7642\u6cd5\u306f\u7d9a\u3051\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u30b0\u30ec\u30fc\u30d7\u30d5\u30eb\u30fc\u30c4\u306a\u3069\u7279\u5b9a\u306e\u98df\u3079\u7269\u3068\u4e00\u7dd2\u306b\u98f2\u3081\u306a\u3044\u85ac\u3082\u3042\u308b<\/h3>\n\n\n\n<p><span class=\"swl-marker mark_orange\"><strong>\u4e00\u90e8\u306e\u30ab\u30eb\u30b7\u30a6\u30e0\u62ee\u6297\u85ac(\u30b8\u30eb\u30c1\u30a2\u30bc\u30e0\u3001\u30d9\u30e9\u30d1\u30df\u30eb\u3001\u30d5\u30a7\u30ed\u30b8\u30d4\u30f3\u306a\u3069)\u306f\u3001\u30b0\u30ec\u30fc\u30d7\u30d5\u30eb\u30fc\u30c4\u3084\u30b0\u30ec\u30fc\u30d7\u30d5\u30eb\u30fc\u30c4\u30b8\u30e5\u30fc\u30b9\u3068\u4e00\u7dd2\u306b\u6442\u308b\u3068\u3001\u85ac\u306e\u8840\u6db2\u4e2d\u306e\u6fc3\u5ea6\u304c\u4e0a\u304c\u3063\u3066\u3001\u526f\u4f5c\u7528\u304c\u5f37\u304f\u51fa\u308b\u53ef\u80fd\u6027<\/strong><\/span>\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"has-text-align-center u-mb-ctrl u-mb-0\">\u98df\u3079\u7269\u30fb\u98f2\u307f\u7269\u3068\u306e\u76f8\u4e92\u4f5c\u7528<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><thead><tr><th>\u964d\u5727\u85ac\u306e\u30bf\u30a4\u30d7<\/th><th>\u907f\u3051\u308b\u3079\u304d\u3082\u306e<\/th><th>\u7406\u7531<\/th><\/tr><\/thead><tbody><tr><td>\u30ab\u30eb\u30b7\u30a6\u30e0\u62ee\u6297\u85ac(\u4e00\u90e8)<\/td><td>\u30b0\u30ec\u30fc\u30d7\u30d5\u30eb\u30fc\u30c4\u3001\u30b0\u30ec\u30fc\u30d7\u30d5\u30eb\u30fc\u30c4\u30b8\u30e5\u30fc\u30b9<\/td><td>\u85ac\u306e\u8840\u4e2d\u6fc3\u5ea6\u304c\u4e0a\u304c\u308a\u3059\u304e\u3066\u526f\u4f5c\u7528\u304c\u5f37\u304f\u51fa\u308b<\/td><\/tr><tr><td>ARB\u3001ACE\u963b\u5bb3\u85ac<\/td><td>\u30ab\u30ea\u30a6\u30e0\u3092\u591a\u304f\u542b\u3080\u98df\u54c1\u306e\u904e\u5270\u6442\u53d6\u3001\u6e1b\u5869\u3057\u304a<\/td><td>\u9ad8\u30ab\u30ea\u30a6\u30e0\u8840\u75c7\u306e\u30ea\u30b9\u30af<\/td><\/tr><tr><td>\u5229\u5c3f\u85ac<\/td><td>\u30a2\u30eb\u30b3\u30fc\u30eb<\/td><td>\u8131\u6c34\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u307e\u308b<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p>\u3053\u308c\u306f\u3001\u30b0\u30ec\u30fc\u30d7\u30d5\u30eb\u30fc\u30c4\u306b\u542b\u307e\u308c\u308b\u300c\u30d5\u30e9\u30ce\u30af\u30de\u30ea\u30f3\u985e\u300d\u3068\u3044\u3046\u6210\u5206\u304c\u3001\u809d\u81d3\u3067<a href=\"https:\/\/www.fda.gov\/consumers\/consumer-updates\/grapefruit-juice-and-some-drugs-dont-mix\">\u85ac\u3092\u5206\u89e3\u3059\u308b\u9175\u7d20\u306e\u50cd\u304d\u3092\u90aa\u9b54\u3059\u308b<\/a>\u305f\u3081\u306b\u8d77\u3053\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u305d\u306e\u7d50\u679c\u3001\u85ac\u304c\u4f53\u306e\u4e2d\u306b\u9577\u304f\u7559\u307e\u308a\u3001\u901a\u5e38\u3088\u308a\u5f37\u3044\u52b9\u679c\u304c\u51fa\u3066\u3057\u307e\u3046\u306e\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u75c7\u72b6\u3068\u3057\u3066\u306f\u3001<span class=\"swl-marker mark_orange\"><strong>\u8840\u5727\u304c\u4e0b\u304c\u308a\u3059\u304e\u308b\u3053\u3068\u306b\u3088\u308b\u7acb\u3061\u304f\u3089\u307f\u3001\u3081\u307e\u3044\u3001\u982d\u75db<\/strong><\/span>\u306a\u3069\u304c\u73fe\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"swell-block-capbox cap_box is-style-onborder_ttl\"><div class=\"cap_box_ttl\"><span>\u30b0\u30ec\u30fc\u30d7\u30d5\u30eb\u30fc\u30c4\u306e\u5f71\u97ff<\/span><\/div><div class=\"cap_box_content\">\n<ul class=\"wp-block-list\">\n<li>\u5f71\u97ff\u306e\u6301\u7d9a\u6642\u9593:\u6570\u6642\u9593\u304b\u3089\u5834\u5408\u306b\u3088\u3063\u3066\u306f\u6570\u65e5\u9593<\/li>\n\n\n\n<li>\u5bfe\u5fdc:\u30ab\u30eb\u30b7\u30a6\u30e0\u62ee\u6297\u85ac\u3092\u98f2\u3093\u3067\u3044\u308b\u9593\u306f\u5b8c\u5168\u306b\u907f\u3051\u308b<\/li>\n<\/ul>\n<\/div><\/div>\n\n\n\n<p>\u30b0\u30ec\u30fc\u30d7\u30d5\u30eb\u30fc\u30c4\u306e\u5f71\u97ff\u306f\u3001\u98df\u3079\u305f\u308a\u98f2\u3093\u3060\u308a\u3057\u3066\u304b\u3089\u6570\u6642\u9593\u3001\u5834\u5408\u306b\u3088\u3063\u3066\u306f\u6570\u65e5\u9593\u7d9a\u304f\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3053\u306e\u305f\u3081\u3001<span class=\"swl-marker mark_orange\"><strong>\u30ab\u30eb\u30b7\u30a6\u30e0\u62ee\u6297\u85ac\u3092\u98f2\u3093\u3067\u3044\u308b\u9593\u306f\u3001\u30b0\u30ec\u30fc\u30d7\u30d5\u30eb\u30fc\u30c4\u3068\u30b0\u30ec\u30fc\u30d7\u30d5\u30eb\u30fc\u30c4\u30b8\u30e5\u30fc\u30b9\u306f\u5b8c\u5168\u306b\u907f\u3051\u308b<\/strong><\/span>\u3053\u3068\u304c\u52e7\u3081\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u307e\u305f\u3001ARB\u3084ACE\u963b\u5bb3\u85ac\u3092\u98f2\u3093\u3067\u3044\u308b\u65b9\u306f\u3001\u30ab\u30ea\u30a6\u30e0\u3092\u591a\u304f\u542b\u3080\u98df\u54c1\u3084\u6e1b\u5869\u3057\u304a(\u30ab\u30ea\u30a6\u30e0\u3092\u542b\u3080\u5869\u306e\u4ee3\u308f\u308a\u306e\u8abf\u5473\u6599)\u3092\u305f\u304f\u3055\u3093\u6442\u308b\u3068\u3001\u8840\u6db2\u306e\u4e2d\u306e\u30ab\u30ea\u30a6\u30e0\u306e\u6fc3\u5ea6\u304c\u9ad8\u304f\u306a\u308a\u3059\u304e\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u9ad8\u30ab\u30ea\u30a6\u30e0\u8840\u75c7\u306f<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC1413606\/\">\u8108\u306e\u30ea\u30ba\u30e0\u304c\u4e71\u308c\u308b\u539f\u56e0<\/a>\u3068\u306a\u308b\u305f\u3081\u6ce8\u610f\u304c\u5fc5\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u5229\u5c3f\u85ac\u3092\u98f2\u3093\u3067\u3044\u308b\u5834\u5408\u306f\u3001\u304a\u9152\u3068\u306e\u7d44\u307f\u5408\u308f\u305b\u306b\u3082\u6ce8\u610f\u304c\u5fc5\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u304a\u9152\u306b\u3082\u5c3f\u3092\u51fa\u3055\u305b\u308b\u4f5c\u7528\u304c\u3042\u308b\u307b\u304b\u3001\u8840\u7ba1\u304c\u5e83\u304c\u3063\u3066\u8840\u5727\u304c\u4e0b\u304c\u308a\u3059\u304e\u305f\u308a\u3001<a href=\"https:\/\/medlineplus.gov\/druginfo\/meds\/a682571.html\">\u526f\u4f5c\u7528\u304c\u5f37\u307e\u3063\u305f\u308a\u3059\u308b<\/a>\u53ef\u80fd\u6027\u304c\u3042\u308b\u305f\u3081\u6ce8\u610f\u304c\u5fc5\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u964d\u5727\u85ac\u306e\u526f\u4f5c\u7528\u306f\u85ac\u306e\u30bf\u30a4\u30d7\u306b\u3088\u3063\u3066\u7570\u306a\u308b<\/h2>\n\n\n\n<p>\u964d\u5727\u85ac\u306f\u5168\u4f53\u7684\u306b\u5b89\u5168\u6027\u304c\u9ad8\u3044\u85ac\u3067\u3059\u304c\u3001\u305d\u308c\u3067\u3082\u526f\u4f5c\u7528\u304c\u5168\u304f\u306a\u3044\u308f\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p>\u526f\u4f5c\u7528\u306e\u7a2e\u985e\u3084\u51fa\u3084\u3059\u3055\u306f\u3001\u85ac\u306e\u30bf\u30a4\u30d7\u306b\u3088\u3063\u3066\u9055\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u5927\u5207\u306a\u306e\u306f\u3001\u3069\u3093\u306a\u526f\u4f5c\u7528\u304c\u8d77\u3053\u308a\u3046\u308b\u304b\u3092\u524d\u3082\u3063\u3066\u77e5\u3063\u3066\u304a\u304f\u3053\u3068\u3068\u3001\u526f\u4f5c\u7528\u304c\u73fe\u308c\u305f\u3068\u304d\u306b\u9069\u5207\u306b\u5bfe\u5fdc\u3059\u308b\u3053\u3068\u3067\u3059\u3002<\/p>\n\n\n\n<p><span class=\"swl-marker mark_orange\"><strong>\u526f\u4f5c\u7528\u306b\u306f\u3001\u85ac\u306e\u50cd\u304d\u304b\u3089\u4e88\u60f3\u3067\u304d\u308b\u3082\u306e(\u8840\u7ba1\u3092\u5e83\u3052\u308b\u3053\u3068\u3067\u9854\u304c\u307b\u3066\u308b\u306a\u3069)\u3068\u3001\u307e\u308c\u306b\u8d77\u3053\u308b\u4e88\u60f3\u3057\u306b\u304f\u3044\u3082\u306e(\u30a2\u30ec\u30eb\u30ae\u30fc\u53cd\u5fdc\u306a\u3069)\u304c\u3042\u308a\u307e\u3059\u3002<\/strong><\/span><\/p>\n\n\n\n<p>\u591a\u304f\u306e\u526f\u4f5c\u7528\u306f\u8efd\u3044\u3082\u306e\u3067\u3001\u4f53\u304c\u85ac\u306b\u6163\u308c\u308b\u306b\u3064\u308c\u3066\u826f\u304f\u306a\u308b\u3053\u3068\u3082\u3042\u308a\u307e\u3059\u304c\u3001\u4e2d\u306b\u306f\u6ce8\u610f\u304c\u5fc5\u8981\u306a\u75c7\u72b6\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u307e\u305f\u3001\u526f\u4f5c\u7528\u306e\u51fa\u3084\u3059\u3055\u306b\u306f\u4eba\u306b\u3088\u3063\u3066\u5dee\u304c\u3042\u308a\u3001\u540c\u3058\u85ac\u3092\u98f2\u3093\u3067\u3082\u526f\u4f5c\u7528\u304c\u51fa\u308b\u4eba\u3068\u51fa\u306a\u3044\u4eba\u304c\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p><span class=\"swl-marker mark_orange\"><strong>\u9ad8\u9f62\u8005\u3001\u814e\u81d3\u306e\u50cd\u304d\u304c\u843d\u3061\u3066\u3044\u308b\u65b9\u3001\u305f\u304f\u3055\u3093\u306e\u85ac\u3092\u98f2\u3093\u3067\u3044\u308b\u65b9\u306a\u3069\u306f\u3001\u526f\u4f5c\u7528\u304c\u51fa\u3084\u3059\u3044\u50be\u5411\u304c\u3042\u308a\u307e\u3059\u3002<\/strong><\/span><\/p>\n\n\n\n<p>\u3042\u308a\u304c\u305f\u3044\u3053\u3068\u306b\u3001\u4eca\u3067\u306f\u305f\u304f\u3055\u3093\u306e\u30bf\u30a4\u30d7\u306e\u964d\u5727\u85ac\u304c\u3042\u308b\u305f\u3081\u3001\u3042\u308b\u85ac\u3067\u526f\u4f5c\u7528\u304c\u554f\u984c\u306b\u306a\u3063\u3066\u3082\u3001\u5225\u306e\u30bf\u30a4\u30d7\u306e\u85ac\u306b\u5909\u3048\u308b\u3053\u3068\u3067\u3001\u526f\u4f5c\u7528\u3092\u907f\u3051\u306a\u304c\u3089\u5341\u5206\u306b\u8840\u5727\u3092\u4e0b\u3052\u3089\u308c\u308b\u3053\u3068\u304c\u307b\u3068\u3093\u3069\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u3067\u306f\u3001\u5404\u30bf\u30a4\u30d7\u306e\u964d\u5727\u85ac\u3067\u3088\u304f\u898b\u3089\u308c\u308b\u526f\u4f5c\u7528\u3068\u3001\u305d\u306e\u5bfe\u51e6\u6cd5\u306b\u3064\u3044\u3066\u8a73\u3057\u304f\u8aac\u660e\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u305d\u308c\u305e\u308c\u306e\u964d\u5727\u85ac\u3067\u3088\u304f\u307f\u3089\u308c\u308b\u526f\u4f5c\u7528<\/h3>\n\n\n\n<p class=\"has-text-align-center u-mb-ctrl u-mb-0\">\u964d\u5727\u85ac\u30bf\u30a4\u30d7\u5225\u306e\u4e3b\u306a\u526f\u4f5c\u7528\u4e00\u89a7<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><thead><tr><th>\u85ac\u306e\u30bf\u30a4\u30d7<\/th><th>\u3088\u304f\u3042\u308b\u526f\u4f5c\u7528<\/th><th>\u983b\u5ea6<\/th><\/tr><\/thead><tbody><tr><td>\u30ab\u30eb\u30b7\u30a6\u30e0\u62ee\u6297\u85ac<\/td><td>\u8db3\u9996\u306e\u3080\u304f\u307f\u3001\u9854\u306e\u307b\u3066\u308a\u3001\u982d\u75db\u3001\u52d5\u60b8\u3001\u4fbf\u79d8<\/td><td>\u6bd4\u8f03\u7684\u591a\u3044<\/td><\/tr><tr><td>ARB<\/td><td>\u3081\u307e\u3044\u3001\u3075\u3089\u3064\u304d\u3001\u3060\u308b\u3055<\/td><td>\u5c11\u306a\u3044<\/td><\/tr><tr><td>ACE\u963b\u5bb3\u85ac<\/td><td>\u7a7a\u54b3\u3001\u3081\u307e\u3044\u3001\u7acb\u3061\u304f\u3089\u307f\u3001\u3060\u308b\u3055<\/td><td>\u7a7a\u54b3\u306f5\u301c35%\u7a0b\u5ea6<\/td><\/tr><tr><td>\u5229\u5c3f\u85ac<\/td><td>\u4f4e\u30ab\u30ea\u30a6\u30e0\u8840\u75c7\u3001\u4f4e\u30ca\u30c8\u30ea\u30a6\u30e0\u8840\u75c7\u3001\u5c3f\u9178\u5024\u4e0a\u6607<\/td><td>\u6bd4\u8f03\u7684\u591a\u3044<\/td><\/tr><tr><td>\u03b2\u906e\u65ad\u85ac<\/td><td>\u3060\u308b\u3055\u3001\u75b2\u308c\u3084\u3059\u3055\u3001\u5f90\u8108\u3001\u624b\u8db3\u306e\u51b7\u3048<\/td><td>\u6bd4\u8f03\u7684\u591a\u3044<\/td><\/tr><tr><td>\u03b1\u906e\u65ad\u85ac<\/td><td>\u8d77\u7acb\u6027\u4f4e\u8840\u5727\u3001\u3081\u307e\u3044\u3001\u3075\u3089\u3064\u304d<\/td><td>\u521d\u56de\u6295\u4e0e\u6642\u306b\u591a\u3044<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p><span class=\"swl-marker mark_orange\"><strong>\u30ab\u30eb\u30b7\u30a6\u30e0\u62ee\u6297\u85ac\u3067\u3088\u304f\u898b\u3089\u308c\u308b\u526f\u4f5c\u7528\u306f\u3001\u8840\u7ba1\u304c\u5e83\u304c\u308b\u3053\u3068\u306b\u3088\u308b\u3082\u306e<\/strong><\/span>\u3067\u3001\u9854\u304c\u307b\u3066\u308b\u3001\u982d\u304c\u75db\u304f\u306a\u308b\u3001\u5fc3\u81d3\u304c\u30c9\u30ad\u30c9\u30ad\u3059\u308b\u3001\u8db3\u9996\u304c\u3080\u304f\u3080\u306a\u3069\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u7279\u306b\u8db3\u306e\u3080\u304f\u307f\u306f\u6bd4\u8f03\u7684\u3088\u304f\u3042\u308a\u307e\u3059\u304c\u3001\u901a\u5e38\u306f\u5065\u5eb7\u4e0a\u5927\u304d\u306a\u554f\u984c\u306b\u306f\u306a\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p>\u307e\u305f\u3001<a href=\"https:\/\/www.nhs.uk\/medicines\/verapamil\/side-effects-of-verapamil\/\">\u30d9\u30e9\u30d1\u30df\u30eb\u3067\u306f\u4fbf\u79d8\u304c\u8d77\u3053\u308a\u3084\u3059\u304f<\/a>\u3001\u9006\u306b<a href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2011\/020198s023lbl.pdf\">\u30cb\u30d5\u30a7\u30b8\u30d4\u30f3\u3067\u306f\u4e0b\u75e2\u304c\u8d77\u3053\u308b<\/a>\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>ARB\u3068ACE\u963b\u5bb3\u85ac\u306f\u526f\u4f5c\u7528\u304c\u6bd4\u8f03\u7684\u5c11\u306a\u3044\u85ac\u3068\u3057\u3066\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u304c\u3001<span class=\"swl-marker mark_orange\"><strong>ARB\u3067\u306f\u3054\u304f\u4e00\u90e8\u306e\u65b9\u306b\u3001ACE\u963b\u5bb3\u85ac\u3067\u306f5\u301c35%\u7a0b\u5ea6\u306e\u65b9\u306b\u7a7a\u54b3<\/strong><\/span>\u304c\u73fe\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p>ACE\u963b\u5bb3\u85ac\u306e\u7a7a\u54b3\u306f\u3001\u306e\u3069\u304c\u30a4\u30ac\u30a4\u30ac\u3059\u308b\u3001\u30ab\u30b5\u30ab\u30b5\u3059\u308b\u3068\u3044\u3063\u305f\u75c7\u72b6\u3067\u3001\u54b3\u6b62\u3081\u3067\u306f\u826f\u304f\u306a\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p>\u3053\u306e\u5834\u5408\u3001ARB\u306b\u5909\u3048\u308b\u3053\u3068\u3067\u75c7\u72b6\u304c\u6cbb\u307e\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p>ACE\u963b\u5bb3\u85ac\u7642\u6cd5\u306e\u4e2d\u6b62\u5f8c\u3001\u4ee3\u66ff\u7642\u6cd5\u3068\u3057\u3066\u30a2\u30f3\u30b8\u30aa\u30c6\u30f3\u30b7\u30f3\u53d7\u5bb9\u4f53\u62ee\u6297\u85ac\uff08ARB\uff09\u3092\u958b\u59cb\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002ARB\u306fACE\u963b\u5bb3\u85ac\u7642\u6cd5\u306e\u518d\u958b\u3088\u308a\u3082\u54b3\u306e\u518d\u767a\u7387\u304c\u4f4e\u3044\u3067\u3059\u3002<\/p>\n<cite>\u5f15\u7528\uff1aNational Center for Biotechnology Information <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK430896\/\">ACE Inhibitors<\/a><\/cite><\/blockquote>\n\n\n\n<p>\u3069\u3061\u3089\u306e\u85ac\u3082\u3001\u3081\u307e\u3044\u3001\u7acb\u3061\u304f\u3089\u307f\u3001\u4f53\u304c\u3060\u308b\u3044\u306a\u3069\u304c\u8d77\u3053\u308b\u3053\u3068\u304c\u3042\u308a\u3001\u307e\u308c\u306b\u8840\u7ba1\u6d6e\u816b(\u9854\u3084\u5507\u304c\u816b\u308c\u308b)\u3068\u3044\u3046\u91cd\u3044\u526f\u4f5c\u7528\u304c\u8d77\u3053\u308b\u53ef\u80fd\u6027\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p><span class=\"swl-marker mark_orange\"><strong>\u5229\u5c3f\u85ac\u306e\u4e3b\u306a\u526f\u4f5c\u7528\u306f\u3001\u4f53\u306e\u4e2d\u306e\u30df\u30cd\u30e9\u30eb\u306e\u30d0\u30e9\u30f3\u30b9\u304c\u5d29\u308c\u308b\u3053\u3068<\/strong><\/span>\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u4f4e\u30ab\u30ea\u30a6\u30e0\u8840\u75c7\u3001\u4f4e\u30ca\u30c8\u30ea\u30a6\u30e0\u8840\u75c7\u304c\u8d77\u3053\u308b\u3068\u3001\u4f53\u304c\u3060\u308b\u3044\u3001\u529b\u304c\u5165\u3089\u306a\u3044\u3001\u7b4b\u8089\u304c\u3064\u308b\u306a\u3069\u306e\u75c7\u72b6\u304c\u73fe\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u307e\u305f\u3001\u5c3f\u9178\u5024\u304c\u4e0a\u304c\u3063\u3066\u75db\u98a8\u306e\u767a\u4f5c\u304c\u8d77\u3053\u308a\u3084\u3059\u304f\u306a\u3063\u305f\u308a\u3001\u8840\u7cd6\u5024\u304c\u5c11\u3057\u4e0a\u304c\u3063\u305f\u308a\u3059\u308b\u3053\u3068\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p><span class=\"swl-marker mark_orange\"><strong>\u03b2\u906e\u65ad\u85ac\u3067\u306f\u3001\u4f53\u304c\u3060\u308b\u3044\u3001\u75b2\u308c\u3084\u3059\u3044\u3001\u8108\u304c\u9045\u304f\u306a\u308b\u3001\u624b\u8db3\u304c\u51b7\u305f\u3044<\/strong><\/span>\u306a\u3069\u304c\u8d77\u3053\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u307e\u305f\u3001\u5598\u606f\u3084COPD\u306e\u65b9\u3067\u306f\u3001\u6c17\u7ba1\u652f\u304c\u7e2e\u3093\u3067\u547c\u5438\u304c\u82e6\u3057\u304f\u306a\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u305f\u3081\u3001\u539f\u5247\u3068\u3057\u3066\u4f7f\u7528\u3092\u907f\u3051\u307e\u3059\u304c\u3001\u75c5\u72b6\u306b\u3088\u308a\u614e\u91cd\u306b\u4f7f\u308f\u308c\u308b\u3053\u3068\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p><span class=\"swl-marker mark_orange\"><strong>\u03b1\u906e\u65ad\u85ac\u3067\u6700\u3082\u6ce8\u610f\u3059\u3079\u304d\u526f\u4f5c\u7528\u306f\u3001\u8d77\u7acb\u6027\u4f4e\u8840\u5727<\/strong><\/span>\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u7279\u306b\u521d\u3081\u3066\u98f2\u3080\u3068\u304d\u3084\u91cf\u3092\u5897\u3084\u3057\u305f\u3068\u304d\u306b\u3001<a href=\"https:\/\/my.clevelandclinic.org\/health\/treatments\/22321-alpha-blockers\">\u7acb\u3061\u4e0a\u304c\u3063\u305f\u3068\u304d\u306e\u3081\u307e\u3044\u3001\u3075\u3089\u3064\u304d<\/a>\u3001\u5834\u5408\u306b\u3088\u3063\u3066\u306f\u6c17\u3092\u5931\u3046\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u526f\u4f5c\u7528\u304c\u51fa\u305f\u3089\u6211\u6162\u305b\u305a\u306b\u533b\u5e2b\u306b\u76f8\u8ac7\u3059\u308b<\/h3>\n\n\n\n<p>\u526f\u4f5c\u7528\u304c\u51fa\u305f\u304b\u3089\u3068\u3044\u3063\u3066\u3001\u5fc5\u305a\u3057\u3082\u85ac\u3092\u3084\u3081\u306a\u3051\u308c\u3070\u306a\u3089\u306a\u3044\u308f\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p><span class=\"swl-marker mark_orange\"><strong>\u75c7\u72b6\u304c\u8efd\u3044\u5834\u5408\u306f\u3001\u4f53\u304c\u85ac\u306b\u6163\u308c\u308b\u306b\u3064\u308c\u3066\u6570\u65e5\u304b\u3089\u6570\u9031\u9593\u3067\u826f\u304f\u306a\u308b\u3053\u3068\u3082\u3042\u308a\u307e\u3059\u3002<\/strong><\/span><\/p>\n\n\n\n<p>\u3057\u304b\u3057\u3001\u6b21\u306e\u3088\u3046\u306a\u75c7\u72b6\u304c\u73fe\u308c\u305f\u5834\u5408\u306f\u3001\u3059\u3050\u306b\u304a\u533b\u8005\u3055\u3093\u306b\u76f8\u8ac7\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"swell-block-capbox cap_box is-style-onborder_ttl\"><div class=\"cap_box_ttl\"><span>\u3059\u3050\u306b\u533b\u5e2b\u306b\u76f8\u8ac7\u3059\u3079\u304d\u75c7\u72b6<\/span><\/div><div class=\"cap_box_content\">\n<ul class=\"wp-block-list\">\n<li>\u5f37\u3044\u3081\u307e\u3044\u3084\u3075\u3089\u3064\u304d\u3067\u7acb\u3063\u3066\u3044\u3089\u308c\u306a\u3044<\/li>\n\n\n\n<li>\u606f\u304c\u5207\u308c\u305f\u308a\u547c\u5438\u304c\u82e6\u3057\u3044<\/li>\n\n\n\n<li>\u9854\u3084\u5507\u3001\u820c\u304c\u816b\u308c\u308b<\/li>\n\n\n\n<li>\u6fc0\u3057\u3044\u982d\u75db<\/li>\n\n\n\n<li>\u80f8\u304c\u75db\u3044<\/li>\n\n\n\n<li>\u5fc3\u81d3\u304c\u30c9\u30ad\u30c9\u30ad\u3059\u308b\u306e\u304c\u6fc0\u3057\u304f\u306a\u308b\u3001\u307e\u305f\u306f\u8108\u304c\u3068\u3066\u3082\u9045\u304f\u306a\u308b<\/li>\n\n\n\n<li>\u624b\u8db3\u306b\u529b\u304c\u5165\u3089\u306a\u304b\u3063\u305f\u308a\u7b4b\u8089\u304c\u3064\u308b<\/li>\n<\/ul>\n<\/div><\/div>\n\n\n\n<p>\u526f\u4f5c\u7528\u304b\u3069\u3046\u304b\u308f\u304b\u3089\u306a\u3044\u75c7\u72b6\u3067\u3082\u3001\u6c17\u306b\u306a\u308b\u3053\u3068\u304c\u3042\u308c\u3070\u304a\u533b\u8005\u3055\u3093\u3084\u85ac\u5264\u5e2b\u306b\u76f8\u8ac7\u3057\u307e\u3057\u3087\u3046\u3002<\/p>\n\n\n\n<p>\u81ea\u5206\u306e\u5224\u65ad\u3067\u98f2\u3080\u306e\u3092\u3084\u3081\u305f\u308a\u3001\u91cf\u3092\u6e1b\u3089\u3057\u305f\u308a\u3059\u308b\u3053\u3068\u306f\u907f\u3051\u3066\u304f\u3060\u3055\u3044\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u526f\u4f5c\u7528\u3092\u8efd\u6e1b\u3059\u308b\u305f\u3081\u306b\u85ac\u306e\u7a2e\u985e\u3084\u91cf\u3092\u8abf\u6574\u3067\u304d\u308b<\/h3>\n\n\n\n<p>\u526f\u4f5c\u7528\u304c\u554f\u984c\u306b\u306a\u308b\u5834\u5408\u3001\u304a\u533b\u8005\u3055\u3093\u306f\u3044\u304f\u3064\u304b\u306e\u5bfe\u5fdc\u3092\u8003\u3048\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"swell-block-capbox cap_box is-style-onborder_ttl\"><div class=\"cap_box_ttl\"><span>\u526f\u4f5c\u7528\u3078\u306e\u5bfe\u5fdc\u65b9\u6cd5<\/span><\/div><div class=\"cap_box_content\">\n<ol class=\"wp-block-list\">\n<li><strong>\u85ac\u306e\u91cf\u3092\u6e1b\u3089\u3059<\/strong>\n<ul class=\"wp-block-list\">\n<li>\u8840\u5727\u3092\u4e0b\u3052\u308b\u52b9\u679c\u3092\u4fdd\u3061\u306a\u304c\u3089\u526f\u4f5c\u7528\u3092\u8efd\u6e1b\u3067\u304d\u306a\u3044\u304b\u691c\u8a0e<\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>\u85ac\u306e\u7a2e\u985e\u3092\u5909\u66f4\u3059\u308b<\/strong>\n<ul class=\"wp-block-list\">\n<li>\u540c\u3058\u30bf\u30a4\u30d7\u306e\u5225\u306e\u85ac\u306b\u5909\u66f4<\/li>\n\n\n\n<li>\u5168\u304f\u9055\u3046\u30bf\u30a4\u30d7\u306e\u85ac\u306b\u5909\u66f4<\/li>\n\n\n\n<li>\u4f8b:ACE\u963b\u5bb3\u85ac\u3067\u7a7a\u54b3 \u2192 ARB\u306b\u5909\u66f4\u3067\u75c7\u72b6\u6539\u5584<\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>\u8907\u6570\u306e\u85ac\u3092\u5c11\u91cf\u305a\u3064\u4f75\u7528\u3059\u308b<\/strong>\n<ul class=\"wp-block-list\">\n<li>\u305d\u308c\u305e\u308c\u306e\u85ac\u306e\u91cf\u3092\u6e1b\u3089\u305b\u308b <\/li>\n\n\n\n<li>\u526f\u4f5c\u7528\u306e\u30ea\u30b9\u30af\u3092\u4e0b\u3052\u306a\u304c\u3089\u5341\u5206\u306a\u964d\u5727\u52b9\u679c\u3092\u5f97\u3089\u308c\u308b<\/li>\n<\/ul>\n<\/li>\n<\/ol>\n<\/div><\/div>\n\n\n\n<p>\u307e\u305a\u3001\u85ac\u306e\u91cf\u3092\u6e1b\u3089\u3059\u3053\u3068\u3067\u526f\u4f5c\u7528\u304c\u8efd\u304f\u306a\u3089\u306a\u3044\u304b\u691c\u8a0e\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u8840\u5727\u3092\u4e0b\u3052\u308b\u52b9\u679c\u3092\u4fdd\u3061\u306a\u304c\u3089\u526f\u4f5c\u7528\u3092\u6e1b\u3089\u305b\u308b\u5834\u5408\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p><span class=\"swl-marker mark_orange\"><strong>\u91cf\u3092\u6e1b\u3089\u3057\u3066\u3082\u526f\u4f5c\u7528\u304c\u826f\u304f\u306a\u3089\u306a\u3044\u5834\u5408\u3084\u3001\u91cf\u3092\u6e1b\u3089\u3059\u3068\u8840\u5727\u304c\u5341\u5206\u306b\u4e0b\u304c\u3089\u306a\u304f\u306a\u308b\u5834\u5408\u306f\u3001\u540c\u3058\u30bf\u30a4\u30d7\u306e\u5225\u306e\u85ac\u306b\u5909\u3048\u305f\u308a\u3001\u5168\u304f\u9055\u3046\u30bf\u30a4\u30d7\u306e\u85ac\u306b\u5909\u3048\u305f\u308a\u3057\u307e\u3059\u3002<\/strong><\/span><\/p>\n\n\n\n<p>\u305f\u3068\u3048\u3070\u3001ACE\u963b\u5bb3\u85ac\u3067\u7a7a\u54b3\u304c\u51fa\u305f\u5834\u5408\u3001ARB\u306b\u5909\u3048\u308b\u3053\u3068\u3067\u54b3\u304c\u6cbb\u307e\u308a\u3001\u540c\u3058\u304f\u3089\u3044\u306e\u8840\u5727\u3092\u4e0b\u3052\u308b\u52b9\u679c\u3092\u4fdd\u3066\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u307e\u305f\u3001\u8907\u6570\u306e\u85ac\u3092\u5c11\u3057\u305a\u3064\u4e00\u7dd2\u306b\u4f7f\u3046\u3053\u3068\u3067\u3001\u305d\u308c\u305e\u308c\u306e\u85ac\u306e\u91cf\u3092\u6e1b\u3089\u3057\u3001\u526f\u4f5c\u7528\u304c\u51fa\u308b\u30ea\u30b9\u30af\u3092\u4e0b\u3052\u306a\u304c\u3089\u5341\u5206\u306b\u8840\u5727\u3092\u4e0b\u3052\u3089\u308c\u308b\u5834\u5408\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u526f\u4f5c\u7528\u3078\u306e\u5bfe\u5fdc\u306f\u4eba\u306b\u3088\u3063\u3066\u5927\u304d\u304f\u9055\u3046\u305f\u3081\u3001\u304a\u533b\u8005\u3055\u3093\u3068\u76f8\u8ac7\u3057\u306a\u304c\u3089\u3001\u81ea\u5206\u306b\u6700\u3082\u5408\u3063\u305f\u85ac\u3068\u91cf\u3092\u898b\u3064\u3051\u3066\u3044\u304f\u3053\u3068\u304c\u5927\u5207\u3067\u3059\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u3088\u304f\u3042\u308b\u8cea\u554f<\/h2>\n\n\n\n<dl class=\"swell-block-faq\" data-q=\"fill-main\" data-a=\"col-text\">\n<div class=\"swell-block-faq__item\"><dt class=\"faq_q\">\u964d\u5727\u85ac\u306f\u4e00\u751f\u98f2\u307f\u7d9a\u3051\u306a\u3044\u3068\u3044\u3051\u306a\u3044\u306e\u3067\u3059\u304b?<\/dt><dd class=\"faq_a\">\n<p>\u5fc5\u305a\u3057\u3082\u4e00\u751f\u98f2\u307f\u7d9a\u3051\u306a\u3051\u308c\u3070\u306a\u3089\u306a\u3044\u308f\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p><span class=\"swl-marker mark_orange\"><strong>\u305f\u3060\u3057\u3001\u591a\u304f\u306e\u65b9\u3067\u306f\u9577\u3044\u9593\u98f2\u307f\u7d9a\u3051\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/strong><\/span><\/p>\n\n\n\n<p>\u964d\u5727\u85ac\u3067\u8840\u5727\u304c\u4e0b\u304c\u3063\u3066\u3044\u308b\u306e\u306f\u3001\u85ac\u304c\u52b9\u3044\u3066\u3044\u308b\u304b\u3089\u3067\u3042\u3063\u3066\u3001\u9ad8\u8840\u5727\u304c\u6cbb\u3063\u305f\u308f\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p>\u85ac\u3092\u3084\u3081\u308b\u3068\u3001\u307b\u3068\u3093\u3069\u306e\u5834\u5408\u3001\u8840\u5727\u306f\u307e\u305f\u4e0a\u304c\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3057\u304b\u3057\u3001\u751f\u6d3b\u7fd2\u6163\u306e\u6539\u5584(\u5869\u5206\u3092\u6e1b\u3089\u3059\u3001\u9069\u6b63\u306a\u4f53\u91cd\u3092\u4fdd\u3064\u3001\u904b\u52d5\u3059\u308b\u7fd2\u6163\u3092\u3064\u3051\u308b\u3001\u304a\u9152\u3092\u63a7\u3048\u308b\u306a\u3069)\u3092\u5fb9\u5e95\u7684\u306b\u884c\u3063\u3066\u3001\u85ac\u306a\u3057\u3067\u3082\u8840\u5727\u304c\u76ee\u6a19\u306e\u5024\u306e\u4e2d\u3067\u5b89\u5b9a\u3057\u3066\u4fdd\u305f\u308c\u308b\u3088\u3046\u306b\u306a\u308c\u3070\u3001\u304a\u533b\u8005\u3055\u3093\u306e\u5224\u65ad\u3067\u85ac\u3092\u6e1b\u3089\u3057\u305f\u308a\u3001\u6700\u7d42\u7684\u306b\u3084\u3081\u305f\u308a\u3067\u304d\u308b\u53ef\u80fd\u6027\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u305f\u3060\u3057\u3001\u305d\u306e\u5834\u5408\u3067\u3082\u3001\u98df\u4e8b\u7642\u6cd5\u3084\u904b\u52d5\u7642\u6cd5\u306f\u4e00\u751f\u7d9a\u3051\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u307e\u305f\u3001\u85ac\u3092\u3084\u3081\u305f\u5f8c\u3082\u5b9a\u671f\u7684\u306b\u8840\u5727\u3092\u6e2c\u3063\u3066\u3001\u307e\u305f\u4e0a\u304c\u3063\u3066\u3044\u306a\u3044\u304b\u78ba\u8a8d\u3059\u308b\u3053\u3068\u304c\u5927\u5207\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u85ac\u3092\u6e1b\u3089\u3057\u305f\u308a\u3084\u3081\u305f\u308a\u3059\u308b\u306e\u306f\u3001\u5fc5\u305a\u304a\u533b\u8005\u3055\u3093\u306e\u6307\u793a\u306e\u3082\u3068\u3067\u884c\u3063\u3066\u304f\u3060\u3055\u3044\u3002<\/p>\n<\/dd><\/div>\n\n\n\n<div class=\"swell-block-faq__item\"><dt class=\"faq_q\">\u964d\u5727\u85ac\u3092\u98f2\u3080\u3068\u526f\u4f5c\u7528\u3067\u592a\u308a\u3084\u3059\u304f\u306a\u308b\u3068\u805e\u304d\u307e\u3057\u305f\u304c\u672c\u5f53\u3067\u3059\u304b?<\/dt><dd class=\"faq_a\">\n<p>\u964d\u5727\u85ac\u306e\u591a\u304f\u306f\u4f53\u91cd\u304c\u5897\u3048\u308b\u3053\u3068\u306b\u76f4\u63a5\u3064\u306a\u304c\u308b\u308f\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p>\u305f\u3060\u3057\u3001\u4e00\u90e8\u306e\u03b2\u906e\u65ad\u85ac\u3067\u306f\u3001<a href=\"https:\/\/www.mayoclinic.org\/diseases-conditions\/high-blood-pressure\/expert-answers\/beta-blockers\/faq-20058385\">\u4f53\u306e\u4ee3\u8b1d\u304c\u5c11\u3057\u843d\u3061\u308b\u3053\u3068\u3067\u4f53\u91cd\u304c\u5897\u3048\u3084\u3059\u304f\u306a\u308b\u53ef\u80fd\u6027<\/a>\u304c\u6307\u6458\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u307e\u305f\u3001\u5229\u5c3f\u85ac\u3092\u3084\u3081\u308b\u3068\u3001\u4f53\u306e\u4e2d\u306e\u6c34\u5206\u304c\u5897\u3048\u3066\u4e00\u6642\u7684\u306b\u4f53\u91cd\u304c\u5897\u3048\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p><span class=\"swl-marker mark_orange\"><strong>\u3082\u3057\u964d\u5727\u85ac\u3092\u98f2\u307f\u59cb\u3081\u3066\u304b\u3089\u660e\u3089\u304b\u306b\u4f53\u91cd\u304c\u5897\u3048\u305f\u5834\u5408\u306f\u3001\u304a\u533b\u8005\u3055\u3093\u306b\u76f8\u8ac7\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/strong><\/span><\/p>\n\n\n\n<p>\u85ac\u306e\u7a2e\u985e\u3092\u5909\u3048\u308b\u3053\u3068\u3067\u826f\u304f\u306a\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u4e00\u65b9\u3067\u3001\u9ad8\u8840\u5727\u305d\u306e\u3082\u306e\u304c\u4f53\u91cd\u304c\u5897\u3048\u308b\u3053\u3068\u3068\u95a2\u4fc2\u3057\u3066\u3044\u308b\u3053\u3068\u3082\u5fd8\u308c\u3066\u306f\u3044\u3051\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p>\u80a5\u6e80\u306f\u9ad8\u8840\u5727\u306e\u5927\u5207\u306a\u539f\u56e0\u306e\u4e00\u3064\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u85ac\u3060\u3051\u306b\u983c\u308b\u306e\u3067\u306f\u306a\u304f\u3001\u9069\u5207\u306a\u98df\u4e8b\u3068\u904b\u52d5\u3067\u4f53\u91cd\u3092\u7ba1\u7406\u3057\u7d9a\u3051\u308b\u3053\u3068\u304c\u3001\u9ad8\u8840\u5727\u6cbb\u7642\u306e\u57fa\u672c\u3067\u3059\u3002<\/p>\n<\/dd><\/div>\n\n\n\n<div class=\"swell-block-faq__item\"><dt class=\"faq_q\">\u30b8\u30a7\u30cd\u30ea\u30c3\u30af\u533b\u85ac\u54c1(\u5f8c\u767a\u54c1)\u3067\u3082\u52b9\u679c\u306f\u540c\u3058\u3067\u3059\u304b?<\/dt><dd class=\"faq_a\">\n<p>\u30b8\u30a7\u30cd\u30ea\u30c3\u30af\u533b\u85ac\u54c1\u306f\u3001\u5148\u767a\u533b\u85ac\u54c1\u3068\u540c\u3058\u6709\u52b9\u6210\u5206\u3092\u4f7f\u3063\u3066\u3044\u3066\u3001\u56fd(\u539a\u751f\u52b4\u50cd\u7701)\u306e\u53b3\u3057\u3044\u5be9\u67fb\u3092\u7d4c\u3066\u627f\u8a8d\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC4540728\/\">\u54c1\u8cea\u3001\u52b9\u304d\u76ee\u3001\u5b89\u5168\u6027\u304c\u5148\u767a\u533b\u85ac\u54c1\u3068\u540c\u3058<\/a>\u3067\u3042\u308b\u3053\u3068\u304c\u78ba\u8a8d\u3055\u308c\u3066\u3044\u308b\u305f\u3081\u3001\u57fa\u672c\u7684\u306b\u306f\u540c\u3058\u52b9\u679c\u304c\u671f\u5f85\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<p><span class=\"swl-marker mark_orange\"><strong>\u305f\u3060\u3057\u3001\u6709\u52b9\u6210\u5206\u4ee5\u5916\u306e\u6dfb\u52a0\u7269(\u9320\u5264\u306e\u8272\u3084\u5f62\u3092\u4f5c\u308b\u6210\u5206\u306a\u3069)\u306f\u9055\u3046\u5834\u5408\u304c\u3042\u308a\u307e\u3059\u3002<\/strong><\/span><\/p>\n\n\n\n<p>\u3053\u306e\u305f\u3081\u3001\u307e\u308c\u306b\u6dfb\u52a0\u7269\u306b\u3088\u308b\u30a2\u30ec\u30eb\u30ae\u30fc\u53cd\u5fdc\u304c\u51fa\u305f\u308a\u3001\u85ac\u306e\u6eb6\u3051\u65b9\u304c\u308f\u305a\u304b\u306b\u9055\u3046\u3053\u3068\u3067\u52b9\u304d\u76ee\u306b\u500b\u4eba\u5dee\u304c\u51fa\u305f\u308a\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u30b8\u30a7\u30cd\u30ea\u30c3\u30af\u533b\u85ac\u54c1\u306f\u5148\u767a\u533b\u85ac\u54c1\u3088\u308a\u5024\u6bb5\u304c\u5b89\u3044\u305f\u3081\u3001\u533b\u7642\u8cbb\u306e\u8ca0\u62c5\u3092\u8efd\u304f\u3067\u304d\u308b\u3068\u3044\u3046\u826f\u3044\u70b9\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3082\u3057\u30b8\u30a7\u30cd\u30ea\u30c3\u30af\u533b\u85ac\u54c1\u306b\u5909\u3048\u3066\u4f55\u304b\u6c17\u306b\u306a\u308b\u3053\u3068\u304c\u3042\u308c\u3070\u3001\u304a\u533b\u8005\u3055\u3093\u3084\u85ac\u5264\u5e2b\u306b\u76f8\u8ac7\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/p>\n<\/dd><\/div>\n\n\n\n<div class=\"swell-block-faq__item\"><dt class=\"faq_q\">\u964d\u5727\u85ac\u3092\u98f2\u307f\u5fd8\u308c\u305f\u3068\u304d\u306f\u3069\u3046\u3059\u308c\u3070\u3044\u3044\u3067\u3059\u304b?<\/dt><dd class=\"faq_a\">\n<p>\u98f2\u307f\u5fd8\u308c\u306b\u6c17\u3065\u3044\u305f\u30bf\u30a4\u30df\u30f3\u30b0\u306b\u3088\u3063\u3066\u5bfe\u5fdc\u304c\u9055\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u6b21\u306b\u98f2\u3080\u6642\u9593\u307e\u3067\u5341\u5206\u306a\u6642\u9593\u304c\u3042\u308b\u5834\u5408\u306f\u3001\u6c17\u3065\u3044\u305f\u6642\u70b9\u30671\u56de\u5206\u3092\u98f2\u3093\u3067\u304f\u3060\u3055\u3044\u3002<\/p>\n\n\n\n<p>\u305f\u3060\u3057\u3001\u6b21\u306b\u98f2\u3080\u6642\u9593\u304c\u8fd1\u3044\u5834\u5408\u306f\u3001\u98f2\u307f\u5fd8\u308c\u305f\u5206\u306f\u98db\u3070\u3057\u3066\u3001\u6b21\u56de\u304b\u3089\u666e\u901a\u901a\u308a\u98f2\u307f\u307e\u3059\u3002<\/p>\n\n\n\n<p><span class=\"swl-marker mark_orange\"><strong>\u7d76\u5bfe\u306b\u3084\u3063\u3066\u306f\u3044\u3051\u306a\u3044\u306e\u306f\u30012\u56de\u5206\u3092\u307e\u3068\u3081\u3066\u98f2\u3080\u3053\u3068\u3067\u3059\u3002<\/strong><\/span><\/p>\n\n\n\n<p>\u8840\u5727\u304c\u4e0b\u304c\u308a\u3059\u304e\u3066\u3001\u3081\u307e\u3044\u3001\u3075\u3089\u3064\u304d\u3001\u6c17\u3092\u5931\u3046\u306a\u3069\u306e\u5371\u967a\u306a\u75c7\u72b6\u304c\u51fa\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"swell-block-capbox cap_box is-style-onborder_ttl\"><div class=\"cap_box_ttl\"><span>\u98f2\u307f\u5fd8\u308c\u3092\u9632\u3050\u5de5\u592b<\/span><\/div><div class=\"cap_box_content\">\n<ul class=\"wp-block-list\">\n<li>\u30b9\u30de\u30fc\u30c8\u30d5\u30a9\u30f3\u306e\u30a2\u30e9\u30fc\u30e0\u6a5f\u80fd\u3092\u4f7f\u3046<\/li>\n\n\n\n<li>\u304a\u85ac\u30ab\u30ec\u30f3\u30c0\u30fc\u3092\u5229\u7528\u3059\u308b<\/li>\n\n\n\n<li>\u98df\u4e8b\u3068\u4e00\u7dd2\u306b\u98f2\u3080\u7fd2\u6163\u3092\u3064\u3051\u308b<\/li>\n\n\n\n<li>\u914d\u5408\u5264\u306b\u5909\u66f4\u3057\u3066\u98f2\u3080\u9320\u6570\u3092\u6e1b\u3089\u3059<\/li>\n<\/ul>\n<\/div><\/div>\n\n\n\n<p>\u98f2\u307f\u5fd8\u308c\u304c\u4f55\u5ea6\u3082\u3042\u308b\u5834\u5408\u306f\u3001\u98f2\u307f\u5fd8\u308c\u306b\u304f\u304f\u3059\u308b\u5de5\u592b\u304c\u5fc5\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u30b9\u30de\u30fc\u30c8\u30d5\u30a9\u30f3\u306e\u30a2\u30e9\u30fc\u30e0\u6a5f\u80fd\u3092\u4f7f\u3046\u3001\u304a\u85ac\u30ab\u30ec\u30f3\u30c0\u30fc\u3092\u4f7f\u3046\u3001\u98df\u4e8b\u3068\u4e00\u7dd2\u306b\u98f2\u3080\u7fd2\u6163\u3092\u3064\u3051\u308b\u306a\u3069\u3001\u81ea\u5206\u306b\u5408\u3063\u305f\u65b9\u6cd5\u3092\u898b\u3064\u3051\u307e\u3057\u3087\u3046\u3002<\/p>\n\n\n\n<p>\u3069\u3046\u3057\u3066\u3082\u98f2\u307f\u5fd8\u308c\u304c\u591a\u3044\u5834\u5408\u306f\u3001\u304a\u533b\u8005\u3055\u3093\u306b\u76f8\u8ac7\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/p>\n\n\n\n<p>\u914d\u5408\u5264(\u8907\u6570\u306e\u6210\u5206\u304c1\u3064\u306e\u9320\u5264\u306b\u5165\u3063\u305f\u3082\u306e)\u306b\u5909\u3048\u308b\u3053\u3068\u3067\u3001\u98f2\u3080\u9320\u6570\u3092\u6e1b\u3089\u305b\u308b\u5834\u5408\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n<\/dd><\/div>\n\n\n\n<div class=\"swell-block-faq__item\"><dt class=\"faq_q\">\u85ac\u3092\u98f2\u3093\u3067\u3044\u308c\u3070\u98df\u4e8b\u5236\u9650\u3084\u904b\u52d5\u306f\u5fc5\u8981\u306a\u3044\u3067\u3059\u304b?<\/dt><dd class=\"faq_a\">\n<p>\u964d\u5727\u85ac\u3092\u98f2\u3093\u3067\u3044\u3066\u3082\u3001\u98df\u4e8b\u7642\u6cd5\u3068\u904b\u52d5\u7642\u6cd5\u306f\u5fc5\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<p><span class=\"swl-marker mark_orange\"><strong>\u3080\u3057\u308d\u3001\u3053\u308c\u3089\u306e\u751f\u6d3b\u7fd2\u6163\u306e\u6539\u5584\u304c\u9ad8\u8840\u5727\u6cbb\u7642\u306e\u57fa\u672c\u3067\u3001\u85ac\u306f\u305d\u308c\u3092\u52a9\u3051\u308b\u3082\u306e\u3068\u3044\u3046\u4f4d\u7f6e\u3065\u3051\u3067\u3059\u3002<\/strong><\/span><\/p>\n\n\n\n<p>\u65e5\u672c\u306e\u9ad8\u8840\u5727\u6cbb\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u3067\u306f\u3001\u751f\u6d3b\u7fd2\u6163\u306e\u6539\u5584\u3068\u3057\u3066\u3001\u4ee5\u4e0b\u304c\u52e7\u3081\u3089\u308c\u3066\u3044\u307e\u3059:<\/p>\n\n\n\n<div class=\"swell-block-capbox cap_box is-style-onborder_ttl\"><div class=\"cap_box_ttl\"><span>\u63a8\u5968\u3055\u308c\u308b\u751f\u6d3b\u7fd2\u6163\u306e\u6539\u5584<\/span><\/div><div class=\"cap_box_content\">\n<ul class=\"wp-block-list\">\n<li>\u5869\u5206\u30921\u65e56g\u672a\u6e80\u306b\u6e1b\u3089\u3059<\/li>\n\n\n\n<li>\u91ce\u83dc\u3084\u679c\u7269\u3092\u7a4d\u6975\u7684\u306b\u98df\u3079\u3066\u3001\u52d5\u7269\u6027\u8102\u80aa\u3084\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3092\u63a7\u3048\u308b<\/li>\n\n\n\n<li>\u9069\u6b63\u306a\u4f53\u91cd\u3092\u4fdd\u3064(BMI25\u672a\u6e80)<\/li>\n\n\n\n<li>\u904b\u52d5\u3084\u4f53\u3092\u52d5\u304b\u3059\u91cf\u3092\u5897\u3084\u3059(\u3067\u304d\u308c\u3070\u6bce\u65e530\u5206\u4ee5\u4e0a\u306e\u6709\u9178\u7d20\u904b\u52d5)<\/li>\n\n\n\n<li>\u304a\u9152\u3092\u63a7\u3048\u308b<\/li>\n\n\n\n<li>\u30bf\u30d0\u30b3\u3092\u3084\u3081\u308b<\/li>\n<\/ul>\n<\/div><\/div>\n\n\n\n<div class=\"swell-block-capbox cap_box is-style-onborder_ttl\"><div class=\"cap_box_ttl\"><span>\u751f\u6d3b\u7fd2\u6163\u6539\u5584\u306e\u52b9\u679c<\/span><\/div><div class=\"cap_box_content\">\n<ul class=\"wp-block-list\">\n<li>\u8840\u5727\u3092\u6570mmHg\u4f4e\u4e0b<\/li>\n\n\n\n<li>\u85ac\u306e\u52b9\u679c\u3092\u9ad8\u3081\u308b<\/li>\n\n\n\n<li>\u5fc5\u8981\u306a\u85ac\u306e\u91cf\u3092\u6e1b\u3089\u305b\u308b\u53ef\u80fd\u6027<\/li>\n<\/ul>\n<\/div><\/div>\n\n\n\n<p>\u3053\u308c\u3089\u306e\u751f\u6d3b\u7fd2\u6163\u306e\u6539\u5584\uff08\u6e1b\u5869\u3001\u6e1b\u91cf\u3001\u904b\u52d5\u306a\u3069\uff09\u3092\u884c\u3046\u3053\u3068\u3067\u3001\u305d\u308c\u305e\u308c\u6570mmHg\u4ee5\u4e0a\u306e\u8840\u5727\u3092\u4e0b\u3052\u308b\u52b9\u679c\u304c\u3042\u308b\u3053\u3068\u304c\u7814\u7a76\u3067\u308f\u304b\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u9805\u76ee\u3092\u7d44\u307f\u5408\u308f\u305b\u308b\u3053\u3068\u3067\u3001\u3055\u3089\u306b\u5927\u304d\u306a\u52b9\u679c\u304c\u671f\u5f85\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u85ac\u306e\u52b9\u679c\u3092\u9ad8\u3081\u3066\u3001\u5fc5\u8981\u306a\u85ac\u306e\u91cf\u3092\u6e1b\u3089\u305b\u308b\u53ef\u80fd\u6027\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u307e\u305f\u3001\u751f\u6d3b\u7fd2\u6163\u306e\u6539\u5584\u306f\u3001\u9ad8\u8840\u5727\u3060\u3051\u3067\u306a\u304f\u3001\u7cd6\u5c3f\u75c5\u3084\u8102\u8cea\u7570\u5e38\u75c7\u3001\u30e1\u30bf\u30dc\u30ea\u30c3\u30af\u30b7\u30f3\u30c9\u30ed\u30fc\u30e0\u306e\u4e88\u9632\u3084\u6539\u5584\u306b\u3082\u3064\u306a\u304c\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u85ac\u306b\u983c\u308a\u3059\u304e\u305a\u3001\u3067\u304d\u308b\u3053\u3068\u304b\u3089\u751f\u6d3b\u7fd2\u6163\u3092\u898b\u76f4\u3057\u3066\u3044\u304d\u307e\u3057\u3087\u3046\u3002<\/p>\n<\/dd><\/div>\n<\/dl>\n<script 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class=\"wp-block-heading\">\u307e\u3068\u3081<\/h2>\n\n\n\n<p>\u964d\u5727\u85ac\u306b\u306f\u3001\u30ab\u30eb\u30b7\u30a6\u30e0\u62ee\u6297\u85ac\u3001ARB\u3001ACE\u963b\u5bb3\u85ac\u3001\u5229\u5c3f\u85ac\u3001\u03b2\u906e\u65ad\u85ac\u3001\u03b1\u906e\u65ad\u85ac\u306a\u3069\u3001\u50cd\u304d\u65b9\u304c\u9055\u3046\u8907\u6570\u306e\u30bf\u30a4\u30d7\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p><span class=\"swl-marker 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class=\"swl-marker mark_orange\"><strong>\u85ac\u3092\u3084\u3081\u305f\u308a\u91cf\u3092\u6e1b\u3089\u3057\u305f\u308a\u3059\u308b\u306e\u306f\u3001\u5fc5\u305a\u304a\u533b\u8005\u3055\u3093\u306e\u6307\u793a\u306b\u5f93\u3063\u3066\u884c\u3063\u3066\u304f\u3060\u3055\u3044\u3002<\/strong><\/span><\/p>\n\n\n\n<p>\u526f\u4f5c\u7528\u304c\u51fa\u305f\u5834\u5408\u306f\u3001\u6211\u6162\u305b\u305a\u306b\u304a\u533b\u8005\u3055\u3093\u306b\u76f8\u8ac7\u3057\u307e\u3057\u3087\u3046\u3002<\/p>\n\n\n\n<p>\u85ac\u306e\u7a2e\u985e\u3084\u91cf\u3092\u8abf\u6574\u3059\u308b\u3053\u3068\u3067\u3001\u526f\u4f5c\u7528\u3092\u8efd\u304f\u3057\u306a\u304c\u3089\u5341\u5206\u306b\u8840\u5727\u3092\u4e0b\u3052\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u5834\u5408\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u307e\u305f\u3001\u751f\u6d3b\u7fd2\u6163\u306e\u6539\u5584\u3082\u5fd8\u308c\u305a\u306b\u7d9a\u3051\u308b\u3053\u3068\u304c\u3001\u9ad8\u8840\u5727\u6cbb\u7642\u3092\u3046\u307e\u304f\u9032\u3081\u308b\u30b3\u30c4\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u964d\u5727\u85ac\u306f\u3001\u8133\u5352\u4e2d\u3084\u5fc3\u7b4b\u6897\u585e\u306a\u3069\u306e\u91cd\u5927\u306a\u75c5\u6c17\u3092\u9632\u3050\u305f\u3081\u306e\u5927\u5207\u306a\u6cbb\u7642\u624b\u6bb5\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u308f\u304b\u3089\u306a\u3044\u3053\u3068\u3084\u4e0d\u5b89\u306a\u3053\u3068\u304c\u3042\u308c\u3070\u3001\u9060\u616e\u306a\u304f\u533b\u7642\u6a5f\u95a2\u306b\u76f8\u8ac7\u3057\u3066\u3001\u7d0d\u5f97\u3057\u305f\u3046\u3048\u3067\u6cbb\u7642\u3092\u7d9a\u3051\u3066\u3044\u304d\u307e\u3057\u3087\u3046\u3002<\/p>\n\n\n\n<div class=\"swell-block-capbox cap_box is-style-onborder_ttl2\"><div class=\"cap_box_ttl\"><span>\u53c2\u8003\u6587\u732e\u30fb\u53c2\u8003\u30b5\u30a4\u30c8<\/span><\/div><div class=\"cap_box_content\">\n<p>\u539a\u751f\u52b4\u50cd\u7701\u300c<a href=\"https:\/\/www.mhlw.go.jp\/content\/10900000\/001338334.pdf\">\u4ee4\u548c5\u5e74 \u56fd\u6c11\u5065\u5eb7\u30fb\u6804\u990a\u8abf\u67fb\u7d50\u679c\u306e\u6982\u8981<\/a>\u300d<\/p>\n\n\n\n<p>PubMed <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/2676257\/\">The effects of antihypertensive drug treatment on the incidence of stroke and of coronary heart disease<\/a><\/p>\n\n\n\n<p>\u7279\u5b9a\u975e\u55b6\u5229\u6d3b\u52d5\u6cd5\u4eba \u65e5\u672c\u9ad8\u8840\u5727\u5b66\u4f1a\u300c<a href=\"https:\/\/www.jpnsh.jp\/data\/jsh2019_gen.pdf\">\u4e00\u822c\u5411\u3051\u300c\u9ad8\u8840\u5727\u6cbb\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f32019\u300d\u89e3\u8aac\u518a\u5b50<\/a>\u300d<\/p>\n\n\n\n<p>Nature <a href=\"https:\/\/www.nature.com\/articles\/s41440-019-0238-2\">Analysis of antihypertensive treatment using real-world Japanese data\u2014the retrospective study of antihypertensives for lowering blood pressure (REAL) study<\/a><\/p>\n\n\n\n<p>ScienceDirect <a href=\"https:\/\/www.sciencedirect.com\/topics\/pharmacology-toxicology-and-pharmaceutical-science\/calcium-channel-blocker-toxicity\">Calcium Channel Blocker Toxicity &#8211; an overview<\/a><\/p>\n\n\n\n<p>PubMed <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32410171\/\">Calcium Channel Blockers in Acute Care: The Links and Missing Links Between Hemodynamic Effects and Outcome Evidence<\/a><\/p>\n\n\n\n<p>U.S. Food and Drug Administration <a href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2016\/019614s053lbl.pdf\">VERELAN (verapamil hydrochloride) sustained-release pellet filled capsules<\/a><\/p>\n\n\n\n<p>National Center for Biotechnology Information <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK537027\/\">Angiotensin II Receptor Blockers (ARB)<\/a><\/p>\n\n\n\n<p>PubMed Central <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC1200815\/\">Angiotensin II receptor blockers<\/a><\/p>\n\n\n\n<p>National Kidney Foundation <a href=\"https:\/\/www.kidney.org\/kidney-topics\/ace-inhibitors-and-arbs\">ACE Inhibitors and ARBs<\/a><\/p>\n\n\n\n<p>KDIGO <a href=\"https:\/\/kdigo.org\/wp-content\/uploads\/2023\/04\/Diabetes-Management-in-Chronic-Kidney-Disease-Consensus-Report-by-the-ADA-and-KDIGO.pdf\">Diabetes Management in Chronic Kidney Disease: A Consensus Report by the ADA and KDIGO<\/a><\/p>\n\n\n\n<p>American Heart Association <a href=\"https:\/\/professional.heart.org\/en\/science-news\/-\/media\/832EA0F4E73948848612F228F7FA2D35.ashx\">2022 AHA \/ ACC \/ HFSA Guideline for the Management of Heart Failure<\/a><\/p>\n\n\n\n<p>PubMed <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/16428706\/\">Angiotensin-converting enzyme inhibitor-induced cough: ACCP evidence-based clinical practice guidelines<\/a><\/p>\n\n\n\n<p>JAMA Network <a href=\"https:\/\/jamanetwork.com\/journals\/jama\/fullarticle\/195626\">Major Outcomes in High-Risk Hypertensive Patients Randomized to Angiotensin-Converting Enzyme Inhibitor or Calcium Channel Blocker vs Diuretic: The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT)<\/a><\/p>\n\n\n\n<p>National Center for Biotechnology Information <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK554579\/\">Antihypertensive Medications<\/a><\/p>\n\n\n\n<p>PubMed Central <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC2249618\/\">Use of recommended medications after myocardial infarction in Austria<\/a><\/p>\n\n\n\n<p>PubMed <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17920367\/\">A meta-analysis of 94,492 patients with hypertension treated with beta blockers to determine the risk of new-onset diabetes mellitus<\/a><\/p>\n\n\n\n<p>National Health Service <a href=\"https:\/\/www.nhs.uk\/medicines\/beta-blockers\/\">Beta blockers<\/a><\/p>\n\n\n\n<p>Best Practice Advocacy Centre New Zealand <a href=\"https:\/\/bpac.org.nz\/2024\/beta-blockers.aspx\">Beta blockers for cardiovascular conditions: one size does not fit all<\/a><\/p>\n\n\n\n<p>PubMed Central <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC7155970\/\">Drug deprescription\u2014withdrawal risk, prevention, and treatment<\/a><\/p>\n\n\n\n<p>PubMed Central <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC8108949\/\">Alpha 1 Adrenoreceptor Antagonists<\/a><\/p>\n\n\n\n<p>U.S. Food and Drug Administration <a href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2021\/019668Orig1s032lbl.pdf\">CARDURA (doxazosin) Label<\/a><\/p>\n\n\n\n<p>American Heart Association Journals <a href=\"https:\/\/www.ahajournals.org\/doi\/10.1161\/cir.0000000000000597\">2017 ACC\/AHA\/AAPA\/ABC\/ACPM\/AGS\/APhA\/ASH\/ASPC\/NMA\/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: Executive Summary<\/a><\/p>\n\n\n\n<p>Nature <a href=\"https:\/\/www.nature.com\/articles\/hr20148\">Chapter 5. Treatment with antihypertensive drugs<\/a><\/p>\n\n\n\n<p>Diabetes Care <a href=\"https:\/\/diabetesjournals.org\/care\/article\/48\/Supplement_1\/S239\/157554\/11-Chronic-Kidney-Disease-and-Risk-Management\">11. Chronic Kidney Disease and Risk Management: Standards of Care in Diabetes\u20142025<\/a><\/p>\n\n\n\n<p>PubMed Central <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC6900198\/\">Treatment patterns of antihypertensive fixed\u2010dose combinations according to age and number of agents prescribed: Retrospective analysis using a Japanese claims database<\/a><\/p>\n\n\n\n<p>PubMed <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/19272490\/\">Combination therapy versus monotherapy in reducing blood pressure: meta-analysis on 11,000 participants from 42 trials<\/a><\/p>\n\n\n\n<p>KDIGO <a href=\"https:\/\/kdigo.org\/wp-content\/uploads\/2016\/10\/KDIGO_BP_Exec_Summary_final.pdf\">Executive summary of the KDIGO 2021 Clinical Practice Guideline for the Management of Blood Pressure in Chronic Kidney Disease<\/a><\/p>\n\n\n\n<p>National Center for Biotechnology Information <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK9626\/\">The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure<\/a><\/p>\n\n\n\n<p>Specialist Pharmacy Service NHS <a href=\"https:\/\/www.sps.nhs.uk\/articles\/advising-on-missed-or-delayed-doses-of-medicines\/\">Advising on missed or delayed doses of medicines<\/a><\/p>\n\n\n\n<p>U.S. Food and Drug Administration <a href=\"https:\/\/www.fda.gov\/consumers\/consumer-updates\/grapefruit-juice-and-some-drugs-dont-mix\">Grapefruit Juice and Some Drugs Don&#8217;t Mix<\/a><\/p>\n\n\n\n<p>PubMed Central <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC1413606\/\">Hyperkalemia Revisited<\/a><\/p>\n\n\n\n<p>MedlinePlus <a href=\"https:\/\/medlineplus.gov\/druginfo\/meds\/a682571.html\">Hydrochlorothiazide<\/a><\/p>\n\n\n\n<p>National Health Service <a href=\"https:\/\/www.nhs.uk\/medicines\/verapamil\/side-effects-of-verapamil\/\">Side effects of verapamil<\/a><\/p>\n\n\n\n<p>U.S. Food and Drug Administration <a href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2011\/020198s023lbl.pdf\">Adalat CC (nifedipine) tablets label<\/a><\/p>\n\n\n\n<p>National Center for Biotechnology Information <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK430896\/\">ACE Inhibitors<\/a><\/p>\n\n\n\n<p>Cleveland Clinic <a href=\"https:\/\/my.clevelandclinic.org\/health\/treatments\/22321-alpha-blockers\">Alpha-Blockers: Uses &amp; Side Effects<\/a><\/p>\n\n\n\n<p>Mayo Clinic <a href=\"https:\/\/www.mayoclinic.org\/diseases-conditions\/high-blood-pressure\/expert-answers\/beta-blockers\/faq-20058385\">Beta blockers: Do they cause weight gain?<\/a><\/p>\n\n\n\n<p>PubMed Central <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC4540728\/\">Regulation of Generic Drugs in Japan: the Current Situation and Future Prospects<\/a><\/p>\n<\/div><\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u5065\u5eb7\u8a3a\u65ad\u3067\u300c\u8840\u5727\u304c\u9ad8\u3044\u3067\u3059\u306d\u300d\u3068\u8a00\u308f\u308c\u305f\u3068\u304d\u3001\u591a\u304f\u306e\u65b9\u304c\u4e0d\u5b89\u3092\u611f\u3058\u308b\u306e\u3067\u306f\u306a\u3044\u3067\u3057\u3087\u3046\u304b\u3002 \u300c\u85ac\u3092\u98f2\u307e\u306a\u3051\u308c\u3070\u3044\u3051\u306a\u3044\u306e\u304b\u300d\u300c\u3069\u3093\u306a\u85ac\u304c\u3042\u308b\u306e\u304b\u300d\u300c\u526f\u4f5c\u7528\u306f\u5927\u4e08\u592b\u306a\u306e\u304b\u300d\u300c\u4e00\u751f\u98f2\u307f\u7d9a\u3051\u306a\u3051\u308c\u3070\u306a\u3089\u306a\u3044\u306e\u304b\u300d\u3068\u3044\u3063\u305f\u7591\u554f\u304c [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":1045,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"swell_btn_cv_data":"","footnotes":""},"categories":[1],"tags":[],"class_list":["post-1044","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-hypertension"],"_links":{"self":[{"href":"https:\/\/gmc.kumamoto.jp\/hypertension\/wp-json\/wp\/v2\/posts\/1044","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/gmc.kumamoto.jp\/hypertension\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/gmc.kumamoto.jp\/hypertension\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/gmc.kumamoto.jp\/hypertension\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/gmc.kumamoto.jp\/hypertension\/wp-json\/wp\/v2\/comments?post=1044"}],"version-history":[{"count":6,"href":"https:\/\/gmc.kumamoto.jp\/hypertension\/wp-json\/wp\/v2\/posts\/1044\/revisions"}],"predecessor-version":[{"id":1563,"href":"https:\/\/gmc.kumamoto.jp\/hypertension\/wp-json\/wp\/v2\/posts\/1044\/revisions\/1563"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/gmc.kumamoto.jp\/hypertension\/wp-json\/wp\/v2\/media\/1045"}],"wp:attachment":[{"href":"https:\/\/gmc.kumamoto.jp\/hypertension\/wp-json\/wp\/v2\/media?parent=1044"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/gmc.kumamoto.jp\/hypertension\/wp-json\/wp\/v2\/categories?post=1044"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/gmc.kumamoto.jp\/hypertension\/wp-json\/wp\/v2\/tags?post=1044"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}